- Clone
- MMD3 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- CD209 antigen-like protein A, dendritic cell-specific ICAM-3-grabbing non-integrin, CIRE, CD209, CDSIGN
- Isotype
- Mouse IgG2c, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
![/MMD3_APC_CD209a_Antibody_102422 /MMD3_APC_CD209a_Antibody_102422](https://d1spbj2x7qk4bg.cloudfront.net/Admin/Public/GetImage.ashx?Image=/Files/Images/media_assets/products/product_images/MMD3_APC_CD209a_Antibody_102422-.png&Width=240&Height=300&altFmImage_path=&Compression=90&Crop=5)
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CHO-DC-SIGN transfected cells were stained with anti-mouse CD209a (DC-SIGN) (clone MMD3) APC (filled histogram) or mouse IgG2c, κ isotype control (open histogram).
Cat # | Size | Price | Quantity Check Availability | Save | ||
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833005 | 25 µg | $100 | ||||
833006 | 100 µg | $293 |
CD209a, is also known as dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin (DC-SIGN) and CIRE. Of the eight DC-SIGN-related receptors in mice, CD209a is considered the closest homolog to human DC-SIGN (CD209). Although both mouse and human counterparts are expressed on monocyte-derived dendritic cells, expression variation has been noted. Mouse CD209a is found on skin and splenic myeloid cells and is highly expressed on plasmacytoid dendritic cells, while human CD209 is expressed on myeloid dendritic cells, placental macrophages, liver and placental endothelial cells. CD209 binds to ICAM-3 (CD50), ICAM-2 (CD102), and Butyrophilin (BTN2A1), and mediates dendritic cell migration and T cell proliferation. It plays a critical role in capturing and internalizing pathogens such as Streptococcus pneumoniae.
Product DetailsProduct Details
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- This monoclonal antibody was raised against a purified extracellular domain of mouse CD209a (DC-SIGN)-IgG1 Fc fusion protein.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- 0.2 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
-
Red Laser (633 nm)
- Application Notes
-
The antibody will bind to both C57 and Balb/C mouse tissues.
- RRID
-
AB_2927969 (BioLegend Cat. No. 833005)
AB_2927969 (BioLegend Cat. No. 833006)
Antigen Details
- Biology Area
- Cell Biology, Neuroinflammation, Neuroscience
- Molecular Family
- CD Molecules
- Antigen References
-
1. Cai M, et al. 2016. Clin. Exp. Immunol. 317-25.
2. Ponichtera HE, et al. 2014. J. Immunol. 4655-65. - Gene ID
- 170786 View all products for this Gene ID
- UniProt
- View information about CD209a on UniProt.org
Related Pages & Pathways
Pages
Related FAQs
Other Formats
View All CD209a Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-mouse CD209a (DC-SIGN) | MMD3 | FC |
PE anti-mouse CD209a (DC-SIGN) | MMD3 | FC |
APC anti-mouse CD209a (DC-SIGN) | MMD3 | FC |
Brilliant Violet 421™ anti-mouse CD209a (DC-SIGN) | MMD3 | FC |
TotalSeq™-B1282 anti-mouse CD209a (DC-SIGN) | MMD3 | PG |
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-mouse CD209a (DC-SIGN)
CHO-DC-SIGN transfected (filled histogram) & CHO-K1 (dashed ... -
PE anti-mouse CD209a (DC-SIGN)
C57BL/6 peritoneal macrophages were first treated with TruSt... CHO-DC-SIGN transfected (filled histogram) and CHO-K1 (dashe... -
APC anti-mouse CD209a (DC-SIGN)
CHO-DC-SIGN transfected cells were stained with anti-mouse C... -
Brilliant Violet 421™ anti-mouse CD209a (DC-SIGN)
CHO-DC-SIGN transfected cells were stained with anti-mouse C... -
TotalSeq™-B1282 anti-mouse CD209a (DC-SIGN)
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