- Clone
- 6-434 (See other available formats)
- Regulatory Status
- RUO
- Workshop
- VIII 80652
- Other Names
- Siglec7 (Sialic-binding Ig like lectin 7), p75, AIRM1
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
339202 | 100 µg | $136 |
Siglec-7, also known as p75/AIRM1, is a 75 kD type I transmembrane protein and a member of the family of sialic acid-binding immunoglobulin-like lectins (Siglecs). It is primarily found on NK cells and monocytes. The cytoplasmic domain of Siglec-7 contains immunoreceptor tyrosine-based inhibitory motif (ITIM). CD328 mediates sialic acid-dependent cell-cell binding and functions as an inhibitory receptor of NK cells. CD328 preferentially binds to sialylated glycans with α2,8 disialyl and α2,6 sialyl residues.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
-
AB_1501162 (BioLegend Cat. No. 339202)
Antigen Details
- Structure
- Type I transmembrane protein, Siglec family member, 75 kD
- Distribution
-
NK cells, monocytes
- Function
- Inhibitory receptor of NK cells
- Ligand/Receptor
- Sialylated glycans (with α2,8 disialyl and α2,6 sialyl residues)
- Cell Type
- Monocytes, NK cells
- Biology Area
- Immunology
- Molecular Family
- CD Molecules, Siglec Molecules
- Antigen References
-
- Avril T, et al. 2006. Infection and Immunity 74:4133
- Avril T, et al. 2004. J. Immunol. 173:6841
- Yamaji T, et al. 2005. Glycobiology 15:667
- Gene ID
- 27036 View all products for this Gene ID
- UniProt
- View information about CD328 on UniProt.org
Related Pages & Pathways
Pages
Related FAQs
Other Formats
View All CD328 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-human CD328 (Siglec-7) | 6-434 | FC |
PE anti-human CD328 (Siglec-7) | 6-434 | FC |
APC anti-human CD328 (Siglec-7) | 6-434 | FC |
Alexa Fluor® 700 anti-human CD328 (Siglec-7) | 6-434 | FC |
PE/Cyanine7 anti-human CD328 (Siglec-7) | 6-434 | FC |
TotalSeq™-C0902 anti-human CD328 (Siglec-7) | 6-434 | PG |
APC/Fire™ 750 anti-human CD328 (Siglec-7) | 6-434 | FC |
PerCP/Cyanine5.5 anti-human CD328 (Siglec-7) | 6-434 | FC |
TotalSeq™-A0902 anti-human CD328 (Siglec-7) | 6-434 | PG |
TotalSeq™-B0902 anti-human CD328 (Siglec-7) | 6-434 | PG |
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
-
Purified anti-human CD328 (Siglec-7)
-
PE anti-human CD328 (Siglec-7)
Human peripheral blood lymphocytes stained with 6-434 PE and... -
APC anti-human CD328 (Siglec-7)
Human peripheral blood lymphocytes were stained with CD56 PE... -
Alexa Fluor® 700 anti-human CD328 (Siglec-7)
Human peripheral blood lymphocytes were stained with CD56 Br... -
PE/Cyanine7 anti-human CD328 (Siglec-7)
Human peripheral blood lymphocytes were stained with CD56 Br... -
TotalSeq™-C0902 anti-human CD328 (Siglec-7)
-
APC/Fire™ 750 anti-human CD328 (Siglec-7)
Human peripheral blood lymphocytes were stained with CD56 Br... -
PerCP/Cyanine5.5 anti-human CD328 (Siglec-7)
Human peripheral blood lymphocytes were stained with CD56 Br... -
TotalSeq™-A0902 anti-human CD328 (Siglec-7)
-
TotalSeq™-B0902 anti-human CD328 (Siglec-7)
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