- Clone
- TUGh4 (See other available formats)
- Regulatory Status
- RUO
- Workshop
- VI C-89
- Other Names
- Common γ chain, γc, IL-2 receptor γ subunit
- Isotype
- Rat IgG2b, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
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338609 | 100 µg | 270 CHF | ||||
338610 | 1 mg | 743 CHF |
Select size of product is eligible for a 40% discount! Promotion valid until September 30, 2024. Exclusions apply. To view full promotion terms and conditions or to contact your local BioLegend representative to receive a quote, visit our webpage.
CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, also known as common γ chain (γc), or IL-2 receptor γ subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15 and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID).
Product DetailsProduct Details
- Verified Reactivity
- Human
- Reported Reactivity
- African Green, Cynomolgus, Rhesus
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Formulation
- 0.2 µm filtered in phosphate-buffered solution, pH 7.2, containing no preservative.
- Endotoxin Level
- Less than 0.01 EU/µg of the protein (< 0.001 ng/µg of the protein) as determined by the LAL test.
- Preparation
- The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
- Concentration
- The antibody is bottled at the concentration indicated on the vial, typically between 2 mg/mL and 3 mg/mL. Older lots may have also been bottled at 1 mg/mL. To obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF™ solution contains no preservative; handle under aseptic conditions.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
-
Application References
(PubMed link indicates BioLegend citation) -
- Itano M, et al. 1996. J. Exp. Med. 178:389
- Kondo M, et al. 1993. Science 262:1874
- RRID
-
AB_2860871 (BioLegend Cat. No. 338609)
AB_2860872 (BioLegend Cat. No. 338610)
Antigen Details
- Structure
- Type I transmembrane glycoprotein, Ig superfamily 64-70 kD
- Distribution
-
T cells, B cells, NK, monocytes, granulocytes
- Ligand/Receptor
- Component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15 and IL-21
- Cell Type
- B cells, Granulocytes, Monocytes, NK cells, T cells
- Biology Area
- Immunology
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors
- Antigen References
-
1. Zola H, et al. eds. 2007. Leukocyte and Stromal Cell Molecules:The CD Markers. Wiely-Liss A John Wiley & Sons Inc, Publication
2. Nakarai T, et al. 1994. J. Exp. Med. 180:241
3. Kawahara A, et al. 1995. Proc. Natl. Acad. Sci. USA. 92:8724
4. Habib T, et al. 2002. Biochemistry. 41:8725
5. Matthews DJ, et al. 1995. Blood 85:38 - Gene ID
- 3561 View all products for this Gene ID
- UniProt
- View information about CD132 on UniProt.org
Related FAQs
- Do you guarantee that your antibodies are totally pathogen free?
-
BioLegend does not test for pathogens in-house aside from the GoInVivo™ product line. However, upon request, this can be tested on a custom basis with an outside, independent laboratory.
- Does BioLegend test each Ultra-LEAF™ antibody by functional assay?
-
No, BioLegend does not test Ultra-LEAF™ antibodies by functional assays unless otherwise indicated. Due to the possible complexities and variations of uses of biofunctional antibodies in different assays and because of the large product portfolio, BioLegend does not currently perform functional assays as a routine QC for the antibodies. However, we do provide references in which the antibodies were used for functional assays and we do perform QC to verify the specificity and quality of the antibody based on our strict specification criteria.
- Does BioLegend test each Ultra-LEAF™ antibody for potential pathogens?
-
No, BioLegend does not test for pathogens in-house unless otherwise indicated. However, we can recommend an outside vendor to perform this testing as needed.
- Have you tested this Ultra-LEAF™ antibody for in vivo or in vitro applications?
-
We don't test our antibodies for in vivo or in vitro applications unless otherwise indicated. Depending on the product, the TDS may describe literature supporting usage of a particular product for bioassay. It may be best to further consult the literature to find clone specific information.
Other Formats
View All CD132 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-human CD132 (common γ chain) | TUGh4 | FC |
PE anti-human CD132 (common γ chain) | TUGh4 | FC |
APC anti-human CD132 (common γ chain) | TUGh4 | FC |
Ultra-LEAF™ Purified anti-human CD132 (common γ chain) | TUGh4 | FC |
TotalSeq™-C1262 anti-human CD132 (common γ chain) | TUGh4 | PG |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human CD132 (common γ chain)
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PE anti-human CD132 (common γ chain)
Human peripheral blood lymphocytes stained with TUGh4 PE -
APC anti-human CD132 (common γ chain)
Human peripheral blood lymphocytes stained with TUGh4 APC -
Ultra-LEAF™ Purified anti-human CD132 (common γ chain)
-
TotalSeq™-C1262 anti-human CD132 (common γ chain)
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