BioLegend Innate Lymphoid Cells
T helper cells are an established part of adaptive immunity, with several classes like Th1, Th2, and Th17 cells being well-studied. Recently, innate counterparts to these lymphoid cells have come into focus. Termed Innate Lymphoid Cells (ILCs), these cells develop from ID2+ precursor cells and also seem to promote functions associated with T helper cells, but do not share their surface markers (e.g. T cell receptors). And while each group originally held several different names, the nomenclature has been adjusted so that most cells fall into the ILC1, ILC2, or ILC3 class. Click on each ILC cell or Development to learn more.

References:

1. Spits, H. et al. 2013. Nat. Rev. Immunol. 13: 145. Pubmed
2. Walker, J. A. et al. 2013. Nat. Rev. Immunol. 13:75. Pubmed
3. Buonocore, S. et al. 2010. Nature 464:1371. Pubmed
4. Killig, M. et al. 2014. Front. Immunol. 5:142. Pubmed

 

IFNg1 IFNg EOMES IL4 IL5 IL13 IL7 RORa GATA3 IL15 tbet tbet tbet tbet IL7 IL7 IL7 rorgt rorgt rorgt rorgt IL22 IL22 IL22 IL17 IL9 Lta tnfa IL17 IFNg NCR NCR
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