BioLegend Maturation Markers
 
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γδ T cell
CD4+ SP
CD8+ SP
DP
ISP
DN4
DN3
DN2
DN1
Tr3
Tr1
Naïve CD4+ T cell
Natural Treg
CD4+ Thymocyte
Pre Pro B
Pro B
Large Pro B
Large Pre B
Small Pre B
NF B
T1
T2
MZB
F0 B/B2
Plasma Cell
B-1 Precursor
B-1
B-1
Immature B
Memory B
Naïve B
Plasma Cell
Pre B
Pro B
Tr B
CDP
cDC
Macrophage
MDP
Monocyte
pDC
Pre-cDC
TIP DC
Ly6C+ monocyte*
Ly6C- monocyte
MDP
Promonocyte
TRM
Tie-2
TAM
M1
M2a
M2b
M2c
Resident Tissue

CD2
CD3
CD7
CD16
CXCR4
NKG2D
TCR α/β(-)
TCR γ/δ

CD3
CD4
CD8(-)
CD25(-)
CD44(-)
CD117(-)
CD127(-)
TCR α/β
TCR γ/δ(-)

CD3
CD4(-)
CD8
CD25(-)
CD44(-)
CD117(-)
CD127(-)
TCR α/β
TCR γ/δ(-)

CD3
CD4
CD8
CD25(-)
CD44(-)
CD117(-)
CD127(-)
TCR α/β
TCR γ/δ(-)

CD3(-)*
CD4 or CD8+
CD25(-)
CD44(-)
CD117(-)
CD127(-)
TCR α/β(-)
TCR γ/δ(-)

CD3(-)*
CD4(-)
CD8(-)
CD25(-)
CD44(-)*
CD117(-)*
CD127(-)
TCR α/β(-)
TCR γ/δ(-)

CD3(-)*
CD4(-)
CD8(-)
CD25
CD44
CD117
CD127(-)*
TCR α/β(-)
TCR γ/δ(-)

CD3(-)
CD4(-)
CD8(-)
CD25
CD44
CD117
CD127
TCR α/β(-)
TCR γ/δ(-)

CD3(-)
CD4(-)
CD8(-)
CD25(-)
CD44
CD117
CD127(-)
TCR α/β(-)
TCR γ/δ(-)

CD3
CD4
CD25
CD62L
CD199 (CCR9)*
CD223 (LAG-3)
CD357 (GITR)
CTLA-4
Foxp3
LAP (TGFβ)
Integrin α4 (CD49d)*
Integrin β7*

CD3
CD4
CD25
CD357 (GITR)
Foxp3(-)
IL-10
IL-15Rα

CD3
CD4
CD25
CD40
CD127(-)
CD134 (OX40)
CD137 (4-1BB)
CD223 (LAG-3)
CD304 (Neuropilin)
CD357 (GITR)
CTLA-4
Foxp3
GARP
IL-10
LAP (TGFβ)

CD3
CD4
CD25(-)
CD44(-)
CD45RA
CD45RB
CD62L
CD127
CD197

CD3
CD4
CD25(-)
CD44(-)
CD117(-)
CD127(-)
Foxp3(-)
TCR α/β

CD19
CD21/35
CD22
CD23
CD24 (HSA)
CD45R (B220)
CD93 (AA4.1)
IgD
IgM

CD19
CD21/35(-)*
CD22
CD23(-)
CD24 (HSA)
CD45R (B220)
CD93 (AA4.1)
IgD(-)*
IgM


CD2
CD19
CD22(-)*
CD24 (HSA)
CD43(-)
CD45R (B220)
CD127
sµ(-)
λ5

BP-1(-)
cµ(-)
CD2(-)
CD19
CD24 (HSA)
CD43
CD45R (B220)
CD117(-)*
CD127
λ5

CD19(-)
CD24 (HSA)(-)*
CD43(-)*
CD45R (B220)
CD117(-)
CD127

CD9
CD16/32
CD19
CD21/35(-)
CD23(-)
IgD(-)
IgM(-)

CD2
CD19
CD21/35(-)
CD22
CD23(-)
CD24 (HSA)
CD45R (B220)
IgD(-)*
IgM

CD19
CD21/35
CD22
CD23(-)
CD24 (HSA)
CD45R (B220)
IgD(-)*
IgM

BP-1
cµ(-)
CD2(-)
CD19
CD22(-)
CD24 (HSA)
CD43
CD45R (B220)
CD117(-)
CD127
λ5

BP-1

CD2(-)
CD19
CD22(-)*
CD24 (HSA)
CD43(-)*
CD45R (B220)
CD127
λ5

CD19
CD21/35
CD22
CD23
CD24 (HSA)(-)*
CD45R (B220)
CD93 (AA4.1)(-)
IgD
IgM(-)*

CD19
CD45R (B220)(-)
CD45RA

CD11b
CD23(-)
CD45R (B220)(-)*
IgD(-)*
IgM

Bcl-2(-)*
CD10
CD19
CD20
CD24 (HSA)
CD27(-)
CD28

CD19
CD20
CD34
CD38
CD45R (B220)

CD19
CD20
CD38
CD40
CD45R (B220)

CD9
CD19(-)*
CD20(-)
CD27
CD31
CD38
CD40
CD95 (FAS)
CD184 (CXCR4)

CD19
CD20
CD23
CD38(-)*
CD40
CD150 (SLAM)
IgD
IgM

CD19
CD20
CD23(-)*
CD27
CD38(-)
CD40
CD150(-)
IgA
IgG

CD19
CD20
CD40
CD45R (B220)
IgM

CD19
CD20
CD27
IgD(-)*
IgM

CD3(-)
CD4(-)
CD8(-)
CD11b(-)
CD11c(-)
CD19(-)
CD115
CD117
CD127 (IL-7Rα)(-)
CD135
CX3CR1
Gr-1(-) (mouse)
MHC II(-) (mouse)
MHC II(-) (human)
NKp46(-)
Sca-1(-) (mouse)
Ter119(-) (mouse)

Lymphoid Tissue†
CD3(-)
CD11c
CD80
CD86
MHC II (mouse)
MHC II (human)

Non-Lymphoid
Tissue (Mucosal)ǂ
CD3(-)
CD11b(-)
CD11c
CD14(-)
CD103
CX3CR1(-)
MHC II (mouse)
MHC II (human)

CD3(-)
CD11b
CD14
CD68
CD107b (Mac-3)
CD115
F4/80 (mouse)
Ly6C (mouse)

CD3(-)
CD11b(-)
CD11c(-)
CD16
CD19(-)
CD34
CD115
CD117
CD127 (IL-7Rα)(-)
CD135
CX3CR1
Gr-1(-) (mouse)
MHC II(-) (mouse)
MHC II(-) (human)
NKp46(-)
Sca-1(-) (mouse)
Ter119(-) (mouse)

CD3(-)
CD11b
CD11c(-)
CD14
CD19(-)
CD49b(-)
CD115 (CSF-1R)
CD117(-)
CD135(-)
CX3CR1
F4/80 (mouse)
Ly6C (mouse)
Ly6G(-)
MHC II(-) (mouse)
MHC II(-) (human)

Mouse
CD3(-)
CD11b(-)
CD11c
CD19(-)
CD45R (B220)
CD115(-) (CSF-1R)
CD317 (BST2) (mouse)
CX3CR1
F4/80(-) (mouse)
Ly6C (mouse)
MHC II (mouse)
MHC II (human)
NKp46(-)

Human
CD11c(-)
CD123
CD303 (BDCA-2)

CD11b
CD11c
CD115
CX3CR1
CD117(-)*
CD135
MHC II(-) (mouse)
MHC II(-) (human)

CD3(-)
CD11b
CD11c
CD19(-)
CD45R (B220)(-)
CD80
CD86
CD107b (Mac-3)
CD115 (CSF-1R)
CX3CR1
Ly6C (mouse)
MHC II (mouse)
MHC II (human)
NKp46(-)
iNOS
TNFα

CCR2
CD3(-)
CD11a/CD18 (LFA-1)
CD11b
CD11c(-)
CD19(-)
CD43
CD62L
CD115 (CSF-1R)
CD117(-)
CD135(-)
CX3CR1
F4/80 (mouse)
Ly6B.2
Ly6C (mouse)
MHC II(-) (mouse)
MHC II(-) (human)
NKp46(-)

CCR2(-)
CD3(-)
CD11a/CD18 (LFA-1)
CD11b
CD11c(-)
CD19(-)
CD43
CD62L(-)
CD115 (CSF-1R)
CD117(-)
CD135(-)
CX3CR1
F4/80 (mouse)
Ly6B.2(-) (mouse)
Ly6C(-) (mouse)
Ly6G(-) (mouse)
MHC II(-) (mouse)
MHC II(-) (human)
NKp46(-)

CD3(-)
CD11b(-)
CD11c(-)
CD16
CD19(-)
CD34
CD115
CD117
CD127 (IL-7Rα)(-)
CD135
CX3CR1
Gr-1(-) (mouse)
MHC II(-) (mouse)
MHC II(-) (human)
NKp46(-)
Sca-1(-) (mouse)
Ter119(-) (mouse)

Mouse
CD13
CD14
CD15
CD33
CD111 (Nectin-1)
CD112 (Nectin-2)
CD115 (CSF-1R)
CD116
CD123
CD131
F4/80
Human
CD11c
CD13
CD14
CD33
CD34(-)
CD36
CD45
CD56 (NCAM)
CD64
CD117(-)
MHC II

Tissue Resident Macrophage phenotype is highly dependent and variable on the type of tissue it is in. See the reference listed below:
Click Here


CCR5
CD11b
CD11c
CD13
CD14
CD16
CD33
CD45
CD115 (CSF-1R) (human)
F4/80 (mouse)
Ly6A/E (Sca-1) (mouse)
Tie-2 (CD202b)

CCR2
CD11b
CD14
CD23
CD45
CD68
CD115 (CSF-1R)
CD163
CD204
CD206
CXCR4 (human)
F4/80 (mouse)
MHC II (mouse)
MHC II (human)
VEGFR1

CCL2 (MCP-1)
CCL3 (MIP-1α)
CCL4
CCL5 (RANTES)
CCL8 (MCP-2)
CCL15 (MIP-1δ)
CCL20 (MIP-3α)
CCR2
CCR7
CD14
CD16
CD32
CD64
CD86
CD121a (IL-1R, Type I/p80)
CD215
CXCL8 (IL-8)
CXCL9 (MIG)
CXCL10 (IP-10)
CXCL11 (ITAC)
CXCL13 (BCA-1/BLC)
CXCL16
IFNγ
IL-1β
IL-6
IL-12
IL-15
IL-23
iNOS
Ly6C (mouse)
MHC II (mouse)
MHC II (human)
TNF-α

Arginase
CCL2 (MCP-1)
CCL16
CCL18
CCL24
CD121b (IL-1R, Type II/p60)
CD124 (IL-4Rα)
CD163
CD181 (CXCR1)
CD182 (CXCR2)
CD206 (MMR)
CD369 (Dectin-1/CLEC7A)
FcεRIα
IL-10
Lectins
MHC II (mouse)
MHC II (human)
Scavenger Receptor

CCL1 (I-309)
CD86
IL-1
IL-6
IL-10
MHC II (mouse)
MHC II (human)
TNF-α

Arginase
CCL16
CCL18
CCR2
CD14
CD51/61
CD124 (IL-4Rα)
CD150 (SLAM)
CD163
CD206 (MMR)
CD210 (IL-10R)
CXCL13 (BCA-1/BLC)
IL-1RA
IL-10
MHC II (mouse)
MHC II (human)
RAGE
Scavenger Receptor
LAP (TGFβ)

To avoid confusion for differentiating these cell types, certain markers were removed due to their 'low' expression. For more information on these cell types, please click the link to see the review.
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