- Clone
- BB7.1 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- HLA-A7, HLA-B*07, HLA Class I histocompatibility antigen B alpha chain
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
![BB7dot1_APC_HLA-B7_Antibody_011717 BB7dot1_APC_HLA-B7_Antibody_011717](https://d1spbj2x7qk4bg.cloudfront.net/Admin/Public/GetImage.ashx?Image=/Files/Images/media_assets/products/product_images/BB7dot1_APC_HLA-B7_Antibody_011717.jpg&Width=240&Height=300&altFmImage_path=&Compression=90&Crop=5)
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Human peripheral blood lymphocytes were stained with APC HLA-B7 (clone BB7.1, filled histogram) or APC mouse IgG1, κ isotype control (open histogram).
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
372405 | 25 tests | 100€ | ||||
372406 | 100 tests | 252€ |
HLA-B belongs to the HLA class I heavy chain paralogues. HLA-B7 is a serotype of HLA-B and one of the common HLA types. MHC class I heavy chains associate with β2-microglobulin and are expressed on nearly all nucleated cells. MHC class I molecules are involved in the presentation of of antigens to CD8+ T cells and thereby play an important role in cell-mediated immune responses and immune surveillance.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Papain solubilized HLA antigen, B7.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
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FC - Quality tested
- Recommended Usage
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Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
- Excitation Laser
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Red Laser (633 nm)
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Application References
(PubMed link indicates BioLegend citation) -
- Dellgren C, et al. 2015. PLoS One 10:e0135385.
- Brodsky F, et al. 1979. Immunol. Rev. 47:3.
- Rancan C, et al. 2015. PLoS Pathog. 11:e1004906.
- Levering W, et al. 2000. Cytometry 42:95.
- RRID
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AB_2650775 (BioLegend Cat. No. 372405)
AB_2650776 (BioLegend Cat. No. 372406)
Antigen Details
- Structure
- Ig superfamily.
- Distribution
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Nearly all cells from HLA-B*07 individuals.
- Function
- Antigen peptide presentation.
- Ligand/Receptor
- TCR, CD8.
- Biology Area
- Immunology
- Molecular Family
- MHC Antigens
- Gene ID
- 3106 View all products for this Gene ID
- Specificity (DOES NOT SHOW ON TDS):
- HLA-B7
- Specificity Alt (DOES NOT SHOW ON TDS):
- HLA-B7
- App Abbreviation (DOES NOT SHOW ON TDS):
- FC
- UniProt
- View information about HLA-B7 on UniProt.org
Related Pages & Pathways
Pages
Other Formats
View All HLA-B7 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-human HLA-B7 | BB7.1 | FC |
PE anti-human HLA-B7 | BB7.1 | FC |
APC anti-human HLA-B7 | BB7.1 | FC |
TotalSeq™-A1247 anti-human HLA-B7 | BB7.1 | PG |
TotalSeq™-C1247 anti-human HLA-B7 | BB7.1 | PG |
TotalSeq™-B1247 anti-human HLA-B7 | BB7.1 | PG |
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human HLA-B7
Human peripheral blood lymphocytes were stained with purifie... -
PE anti-human HLA-B7
Human peripheral blood lymphocytes were stained with PE HLA-... -
APC anti-human HLA-B7
Human peripheral blood lymphocytes were stained with APC HLA... -
TotalSeq™-A1247 anti-human HLA-B7
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TotalSeq™-C1247 anti-human HLA-B7
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TotalSeq™-B1247 anti-human HLA-B7
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