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- Clone
- B6 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- T cell receptor V δ 2, TRDV2, TCRDV102S1
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
Human peripheral blood lymphocytes stained with CD3 PE and B6 PerCP (top) or mouse IgG1, κ isotype control PerCP (bottom). -
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 331410 | 100 tests | 235€ | ||||
The Vδ2 TCR is a variant of the TCR δ chain expressed on a subset of γ/δ T cells. Vγ9Vδ2 T lymphocytes, a major γ/δ T cell subset in humans, recognize phosphoantigens, certain tumor cells, and cells treated with aminobisphosphonates. This cell population displays cytolytic activity against various tumor cells. The γ/δ TCR is an heterodimeric TCR complex composed of covalently bound γ and δ chains involved in antigen recognition and the non-covalently associated monomorphic proteins CD3δ, γ, ε, and ζ chains.
Product DetailsProduct Details
- Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PerCP under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
* PerCP has a maximum absorption of 482 nm and a maximum emission of 675 nm. -
Application References
(PubMed link indicates BioLegend citation) -
- Rojas RE, et al. 2005. J. Infect. Dis. 192:1806.
- Correia DV, et al. 2011. Blood 118:992. (FC) PubMed
- Product Citations
- RRID
-
AB_1877263 (BioLegend Cat. No. 331410)
Antigen Details
- Structure
- Ig superfamily member, TCR γ/δ with CD3 forms the CD3/TCR complex
- Distribution
-
Expressed on majority of peripheral γ/δT cells
- Function
- Antigen recognition, T cell activation
- Ligand/Receptor
- Peptide bound to MHC
- Cell Type
- T cells
- Biology Area
- Adaptive Immunity, Immunology
- Molecular Family
- TCRs
- Antigen References
-
1. Scotet E, et al. 2005. Immunity 22:71.
2. Rincon-Orozco B, et al. 2005. J. Immunol. 175:2144. - Gene ID
- 6964 View all products for this Gene ID
- UniProt
- View information about TCR Vdelta2 on UniProt.org
Related FAQs
- How stable is PerCP/Cy5.5 tandem as compared to PerCP alone?
-
PerCP/Cy5.5 is quite photostable and also better than PerCP alone in withstanding fixation.
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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