- Clone
- S15049I (See other available formats)
- Regulatory Status
- RUO
- Other Names
- M130, MM130, SCARI1
- Isotype
- Rat IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
![S15049I_PE_CD163_Antibody_080819.png S15049I_PE_CD163_Antibody_080819.png](https://d1spbj2x7qk4bg.cloudfront.net/Admin/Public/GetImage.ashx?Image=/Files/Images/media_assets/products/product_images/S15049I_PE_CD163_Antibody_080819.png&Width=240&Height=300&altFmImage_path=&Compression=90&Crop=5)
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C57BL/6 bone marrow were stained with CD11b APC and CD163 (clone S15049I) PE (left) or rat IgG2a, κ PE isotype control (right). Data shown was gated on total bone marrow cells.
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
155307 | 25 µg | 113€ | ||||
155308 | 100 µg | 292€ |
CD163 is a member of the group B scavenger receptor cysteine-rich superfamily, also known as GHI/61, M130, RM3/1, p155, hemoglobin-haptoglobin complex receptor, or macrophage-associated antigen. It is a 134 kD (non-reduced)/155 kD (reduced) glycoprotein primarily expressed on macrophages, Kupffer cells, monocytes, a subset of dendritic cells, and a subset of hematopoietic stem/progenitor cells. CD163 binds to haptoglobin-hemoglobin complex and TWEAK, and plays a role in clearing hemoglobin and regulating cytokine production by macrophages. Membrane CD163 can be cleaved by metalloproteinases (MMP), resulting in a soluble form. Elevated serum level of sCD163 has been implicated in many kinds of inflammatory diseases.
Product DetailsProduct Details
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Recombinant mouse CD163 extracellular domain
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
-
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Product Citations
-
- RRID
-
AB_2814061 (BioLegend Cat. No. 155307)
AB_2814062 (BioLegend Cat. No. 155308)
Antigen Details
- Structure
- Type 1 transmembrane glycoprotein, 134 kD (non-reduced)/155 kD (reduced) glycoprotein
- Distribution
-
Macrophages, Kupffer cells, monocytes, a subset of dendritic cells, and a subset of hematopoietic stem/progenitor cells
- Function
- Binds to haptoglobin-hemoglobin complex and TWEAK, and plays a role in clearing hemoglobin and regulating cytokine production by macrophages
- Biology Area
- Immunology
- Molecular Family
- CD Molecules
- Gene ID
- 93671 View all products for this Gene ID
- Specificity (DOES NOT SHOW ON TDS):
- CD163
- Specificity Alt (DOES NOT SHOW ON TDS):
- CD163
- App Abbreviation (DOES NOT SHOW ON TDS):
- FC
- UniProt
- View information about CD163 on UniProt.org
Related Pages & Pathways
Pages
Related FAQs
- What type of PE do you use in your conjugates?
- We use R-PE in our conjugates.
Other Formats
View All CD163 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-mouse CD163 | S15049I | FC,IHC-F |
Brilliant Violet 421™ anti-mouse CD163 | S15049I | FC |
PE anti-mouse CD163 | S15049I | FC |
APC anti-mouse CD163 | S15049I | FC |
TotalSeq™-A0417 anti-mouse CD163 | S15049I | PG |
TotalSeq™-B0417 anti-mouse CD163 | S15049I | PG |
TotalSeq™-C0417 anti-mouse CD163 | S15049I | PG |
PE/Dazzle™ 594 anti-mouse CD163 Antibody | S15049I | FC |
KIRAVIA Blue 520™ anti-mouse CD163 Antibody | S15049I | FC |
PE/Cyanine7 anti-mouse CD163 Antibody | S15049I | FC |
APC/Fire™ 810 anti-mouse CD163 Antibody | S15049I | FC |
APC/Cyanine7 anti-mouse CD163 | S15049I | FC |
Brilliant Violet 711™ anti-mouse CD163 | S15049I | FC |
Brilliant Violet 605™ anti-mouse CD163 | S15049I | FC |
Alexa Fluor® 647 anti-mouse CD163 | S15049I | FC |
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-mouse CD163
C57BL/6 mouse peritoneal macrophages were cultured for seven... C57BL/6 bone marrow were stained with CD11b APC and purified... C57BL/6 mouse frozen spleen section was fixed with 4% parafo... C57BL/6 mouse frozen liver section was fixed with 4% parafor... -
Brilliant Violet 421™ anti-mouse CD163
C57BL/6 bone marrow were stained with CD11b APC and CD163 Br... -
PE anti-mouse CD163
C57BL/6 bone marrow were stained with CD11b APC and CD163 (c... -
APC anti-mouse CD163
C57BL/6 bone marrow cells were stained with CD11b PE and CD1... -
TotalSeq™-A0417 anti-mouse CD163
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TotalSeq™-B0417 anti-mouse CD163
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TotalSeq™-C0417 anti-mouse CD163
-
PE/Dazzle™ 594 anti-mouse CD163 Antibody
C57BL/6 mouse bone marrow cells were stained with CD11b APC ... -
KIRAVIA Blue 520™ anti-mouse CD163 Antibody
C57BL/6 mouse bone marrow cells were stained with CD11b APC ... -
PE/Cyanine7 anti-mouse CD163 Antibody
C57BL/6 mouse bone marrow cells were stained with CD11b APC ... -
APC/Fire™ 810 anti-mouse CD163 Antibody
C57BL/6 mouse bone marrow cells were stained with anti-mouse... -
APC/Cyanine7 anti-mouse CD163
C57BL/6 mouse bone marrow cells were stained with anti-mouse... -
Brilliant Violet 711™ anti-mouse CD163
C57BL/6 mouse bone marrow were stained with anti-mouse CD11b... -
Brilliant Violet 605™ anti-mouse CD163
C57BL/6 bone marrow cells were stained with anti-mouse CD11b... -
Alexa Fluor® 647 anti-mouse CD163
C57BL/6 bone marrow cells were stained with anti-mouse CD11b...
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