Purified anti-human EphA1 Antibody

Pricing & Availability
Clone
A20047D (See other available formats)
Regulatory Status
RUO
Other Names
EPH Receptor A1, Erythropoietin-Producing Hepatoma Receptor, Tyrosine-Protein Kinase Receptor EPH, Ephrin Type-A Receptor 1, EC 2.7.10.1, HEpha1, EPHT1, EPHT, EPH, Erythropoietin-Producing Hepatoma Amplified Sequence
Isotype
Rat IgG2a, κ
Ave. Rating
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Product Citations
publications
A20047D_PURE_EphA1_Antibody_080422
Human peripheral blood lymphocytes were stained with anti-human CD4 APC and purified anti-human EphA1 (clone A20047D) (left) or rat IgG2a, κ isotype control (right) followed by PE anti-rat IgG.
  • A20047D_PURE_EphA1_Antibody_080422
    Human peripheral blood lymphocytes were stained with anti-human CD4 APC and purified anti-human EphA1 (clone A20047D) (left) or rat IgG2a, κ isotype control (right) followed by PE anti-rat IgG.
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383902 100 µg 336€
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Description

Ephrin type-A receptor 1 (hEpha1), also known as EPH tyrosine kinase belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. The protein consists of 976 a.a. with a molecular weight of 108 kD. The Eph subfamily represents the largest group of receptor protein tyrosine kinases and is divided into two major subclasses: ephrin-A and ephrin-B. They have been implicated in various developmental processes, including axonal guidance, angiogenesis, morphogenesis and carcinogenesis and widely expressed in differentiated epithelial cells in the bone marrow, spleen, thymus, and testis.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Rat
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2927851 (BioLegend Cat. No. 383902)

Antigen Details

Structure
The protein consists of 976 a.a. with a molecular weight of 108 kD.
Distribution

Cytoplasmic and membranous expression in most tissues, including parathyroid gland

Function
Kinase, receptor, transferase, tyrosine-protein kinase. EphA1/A2 and ephrin‐A1 are over‐expressed or downregulated in various types of cancer.
Interaction
EphA1/A2 and ephrin‐A1 are correlated with tumor malignancy and prognosis.
Ligand/Receptor
Ephrin-A1
Cell Type
B cells, Endothelial cells, Epithelial cells, T cells, Thymocytes
Biology Area
Cancer Biomarkers, Cell Adhesion, Immunology
Molecular Family
Protein Kinases/Phosphatase
Antigen References
  1. Katsuaki L and Yoshiro M. 2019. Cancer Sci. 110:841.
  2. Holen L, et al. 2010. J Leukoc Biol. 87:1059-68.
Gene ID
2041 View all products for this Gene ID
UniProt
View information about EphA1 on UniProt.org

Related FAQs

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Go To Top Version: 2    Revision Date: 08.04.2022

For Research Use Only. Not for diagnostic or therapeutic use.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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