Loading...

Purified anti-mouse/human CD11b Antibody

Pricing & Availability
Clone
M1/70 (See other available formats)
Regulatory Status
RUO
Other Names
αM integrin, Mac-1, Mo1, CR3, Ly-40, C3biR, ITGAM
Isotype
Rat IgG2b, κ
Ave. Rating
Submit a Review
Product Citations
publications
1-M1slash70_Purified_042706
C57BL/6 mouse bone marrow cells were stained with purified CD11b (clone M1/70) (filled histogram) or rat IgG2b, κ isotype control (open histogram), followed by anti-rat IgG FITC (gated on total cells).
  • 1-M1slash70_Purified_042706
    C57BL/6 mouse bone marrow cells were stained with purified CD11b (clone M1/70) (filled histogram) or rat IgG2b, κ isotype control (open histogram), followed by anti-rat IgG FITC (gated on total cells).
  • 2-M170_Pure_CD11b_Antibody_IHC_102418
    Fresh, frozen mouse spleen was stained with purified CD11b clone M1/70 conjugated and detected with a Cy5 CODEX™ oligonucleotide duplex (red). Samples were counterstained with TCR FITC (green). Data generated at Akoya Biosciences, Inc. using the CODEX™ technology.
Cat # Size Price Quantity Check Availability Save
101201 50 µg 24€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
101202 500 µg 92€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

Product Details
Technical data sheet

Product Details

Reactivity
Mouse,Human,Cynomolgus,Rhesus
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
C57BL/10 splenocytes
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
IHC-F, CyTOF® - Verified
IP, ICC - Reported in the literature, not verified in house
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Clone M1/70 has been verified for immunocytochemistry (ICC) and frozen immunohistochemistry (IHC-F).

Additional reported applications (for relevant formats of this clone) include: immunoprecipitation1,4, in vitro blocking3,9,12, depletion2,8, immunofluorescence microscopy6,7,10, immunohistochemistry of acetone-fixed frozen sections5,11-13, and spatial biology (IBEX)35,36. For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) (Cat. No. 101248).

Application References

(PubMed link indicates BioLegend citation)
  1. Springer T, et al. 1978. Eur. J. Immunol. 8:539. (IP)
  2. Ault K and Springer T. 1981. J. Immunol. 126:359. (Deplete)
  3. Springer TA, et al. 1982. Immunol. Rev. 68:171. (Block)
  4. Ho MK and Springer TA. 1983. J. Biol. Chem. 258:2766. (IP)
  5. Flotte TJ, et al. 1983. Am. J. Pathol. 111:112. (IHC)
  6. Noel GJ, et al. 1990. J. Clin. Invest. 85:208. (IF)
  7. Allen LA and Aderem A. 1996. J. Exp. Med. 184:627 (IF)
  8. D'Amico A and Wu L. 2003. J. Exp. Med. 198:293. (Deplete)
  9. Brickson SJ, et al. 2003. Appl Physiol. 95:969. (Block)
  10. Clatworthy MR and Smith KG. 2004. J. Exp. Med. 199:717. (IF)
  11. Hata H, et al. 2004. J. Clin. Invest. 114:582. (IHC)
  12. Zhang Y, et al. 2002. J. Immunol. 168:3088. (IHC)
  13. Iwasaki A and Kelsall BL. 2001. J. Immunol. 166:4884 (IHC, FC)
  14. Tailleux L. 2003. J. Exp. Med. 197:121. (Block, FC)
  15. Olver S, et al. 2006. Cancer Research 66:571. (FC)
  16. Tan SL, et al. 2006. J. Immunol. 176:2872. (FC) PubMed
  17. Ponomarev ED, et al. 2006. J. Immunol. 176:1402. (FC)
  18. Dzhagalov I, et al. 2007. Blood 109:1620. (FC)
  19. Fazilleau N, et al. 2007. Nature Immunol. 8:753.
  20. Rasmussen JW, et al. 2006. Infect. Immun.74:6590. PubMed
  21. Napimoga MH, et al. 2008. J. Immunol. 180:609. PubMed
  22. Elqaraz-Carmon V, et al. 2008. J. Lipid. Res. 49:1894. PubMed
  23. Kim DD, et al. 2008. Blood 112:1109. PubMed
  24. Guo Y, et al. 2008. Blood 112:480. PubMed
  25. Norian LA, et al. 2009. Cancer Res. 69:3086. (FC) PubMed
  26. Baumgartner CK, et al. 2010. J. Immunol. 184:573. PubMed
  27. Charles N, et al. 2010. Nat. Med. 16:701. (FC) PubMed
  28. Whiteland J, et al. 1995. J. Histochem. Cytochem. 43:313. (IHC)
  29. Weber GF, et al. 2014. J Exp Med. 211:1243. PubMed
  30. Ashok A, et al. 2015. Toxicol Sci. 143:64. PubMed
  31. Price PJ, et al. 2015. J Immunol. 194:1164. PubMed
  32. Doni A, et al. 2015. J Exp Med. 212:905. PubMed
  33. Ferreira R, et al. 2016. J Infect Dis. 213: 669 - 673. PubMed
  34. Peterson VM, et al. 2017. Nat. Biotechnol. 35:936. (PG)
  35. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  36. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Rissiek B, et al. 2017. Sci Rep. . 10.1038/s41598-017-16613-w. PubMed
  2. Madsen D, et al. 2017. Cell Rep.. 10.1016/j.celrep.2017.12.011. PubMed
  3. Bachran C, et al. 2017. Sci Rep.. 10.1038/s41598-017-17948-0. PubMed
  4. An Y et al. 2018. Cell reports. 25(3):702-714 . PubMed
  5. Winter C, et al. 2018. Cell Metab. 28:175. PubMed
  6. Chevrier S, et al. 2018. Cell Syst. 0.675. PubMed
  7. Zhou N et al. 2018. Protein & cell. 10(2):87-103 . PubMed
  8. Nagatake T, et al. 2018. Int Immunol. 30:471. PubMed
  9. Peterson EJ, et al. 2019. Mol Syst Biol. 15:e8584. PubMed
  10. Wagner J et al. 2019. Cell. 177(5):1330-1345 . PubMed
  11. Torika N, et al. 2018. CNS Neurosci Ther. 24:231. PubMed
  12. Axelrod HD, et al. 2019. Mol Cancer Res. 17:356. PubMed
  13. Zhou LJ et al. 2019. Cell Rep. 27(13):3844-3859 . PubMed
  14. Peng J, et al. 2019. Mol Brain. 12:71. PubMed
  15. Ortiz A, et al. 2019. Cancer Cell. 35:33:00. PubMed
  16. Lechner AJ et al. 2017. Cell stem cell. 21(1):120-134 . PubMed
  17. Dave K et al. 2017. eLife. 6 pii: e23382. PubMed
  18. Arimura K, et al. 2017. Mucosal Immunol. 1.08125. PubMed
  19. He X, et al. 2017. Cancer Biol Ther. 0.815277778. PubMed
  20. Stacey MA, et al. 2017. J Clin Invest. 127:1463. PubMed
  21. Ajona D, et al. 2017. Cancer Discov. 0.773611111. PubMed
  22. Akiel M, et al. 2017. Cancer Res. 77:4014. PubMed
  23. Fino KK, et al. 2017. Sci Rep. 5.334722222. PubMed
  24. Kawabe T, et al. 2017. Sci Immunol. 2:eaam9315. PubMed
  25. Goel S, et al. 2017. Nature. 548:471. PubMed
  26. Yamasaki T, et al. 2018. J Virol. 92:e01458. PubMed
  27. Shirakawa K, et al. 2017. PLoS One. 12:e0186303. PubMed
  28. Nolin JD, et al. 2017. JCI Insight. 2:e94929. PubMed
  29. Regan–Komito D, et al. 2017. Front Immunol. 1.459027778. PubMed
  30. Chartrand K, et al. 2018. Front Immunol. 1.642361111. PubMed
  31. Cao Q, et al. 2018. Am J Physiol Renal Physiol. 314:F561. PubMed
  32. Hoves S, et al. 2018. J Exp Med. 215:859. PubMed
  33. Burrello C, et al. 2018. Front Med (Lausanne). 5:21. PubMed
  34. Manni M, et al. 2018. Nat Immunol. 1.074305556. PubMed
  35. Wicki S, et al. 2018. Int J Mol Sci. 1.266666667. PubMed
  36. Pushalkar S, et al. 2018. Cancer Discov. 0.613194444. PubMed
  37. Lee JY, et al. 2018. Front Immunol. 0.678472222. PubMed
  38. Tong CF, et al. 2018. Am J Physiol Cell Physiol. 315:C409. PubMed
  39. Kikuchi K, et al. 2018. J Immunol. 201:635. PubMed
  40. Diao J, et al. 2018. J Immunol. 201:1306. PubMed
  41. Chung MI, et al. 2018. Am J Respir Cell Mol Biol. 59:706. PubMed
  42. Ito Y, et al. 2018. J Exp Med. 215:2617. PubMed
  43. Zhao L, et al. 2018. Nat Med. 24:1536. PubMed
  44. McLeod RL, et al. 2018. Oncotarget. 9:34459. PubMed
  45. Haney MS, et al. 2018. Nat Genet. 50:1716. PubMed
  46. Wang Y, et al. 2019. Biomed Res Int. 2019:5756189. PubMed
  47. Tang B, et al. 2019. Oncolytic Virother. 8:03. PubMed
  48. Chen S, et al. 2018. Immunohorizons. 0.345138889. PubMed
  49. Yang C, et al. 2019. MBio. 10:e00595-19. PubMed
  50. Hsieh JY, et al. 2019. APL Bioeng. 3:016103. PubMed
  51. Arnold IC, et al. 2019. PLoS Pathog. 15:e1007866. PubMed
  52. Andrews AR, et al. 2019. Cancer Cell Int. 0.955555556. PubMed
  53. Gartlan KH, et al. 2019. Blood Adv. 2.110416667. PubMed
  54. Larson–Casey JL, et al. 2019. J Clin Invest. 129:4962. PubMed
  55. Abboud G, et al. 2018. Front Immunol. 9:1973. PubMed
  56. Wagner AK, et al. 2017. Nat Commun. 8:15627. PubMed
  57. Cole C, et al. 2018. Nucleic Acids Res. 46:e62. PubMed
  58. Fritz Y, et al. 2017. J Invest Dermatol. 137:696. PubMed
  59. Wolf Y, et al. 2017. J Exp Med. 214:905. PubMed
  60. Roussey JA, et al. 2017. J Immunol. 199:3535. PubMed
  61. Davies CL, et al. 2019. Front Immunol. 10:1048. PubMed
  62. Lee YJ, et al. 2018. Front Microbiol. 9:83. PubMed
  63. Zhang J, et al. 2019. Onco Targets Ther. 12:4985. PubMed
  64. Shao Y, et al. 2017. Onco Targets Ther. 10:2675. PubMed
  65. Mazor R, et al. 2018. Proc Natl Acad Sci U S A. 115:E733. PubMed
  66. Wang W, et al. 2018. Cancer Cell. 34:757. PubMed
  67. Liu T, et al. 2020. Sci Adv. 6:eaay1497. PubMed
  68. Tsubaki T, et al. 2018. Oncotarget. 9:11209. PubMed
  69. Silvestre-Roig C, et al. 2019. Nature. 569:236. PubMed
  70. Seelige R, et al. 2018. Sci Rep. 8:13670. PubMed
  71. Paharik AE, et al. 2017. Cell Host Microbe. 22:746. PubMed
  72. Kim D, et al. 2019. Immune Netw. 19:e32. PubMed
  73. Kim SJ, et al. 2017. Nat Immunol. 18:1016. PubMed
  74. Yoon BH, et al. 2018. Mol Cells. 41:953. PubMed
  75. Umemoto T, et al. 2017. EMBO J. 36:2390. PubMed
  76. Kapellos TS, et al. 2017. Mediators Inflamm. 2017:4315412. PubMed
  77. Nascimento DC, et al. 2017. Nat Commun. 8:14919. PubMed
  78. Daley D, et al. 2017. Nat Med. 23:556. PubMed
  79. Hoffmann FM, et al. 2018. Front Immunol. 9:1046. PubMed
  80. Wei S, et al. 2019. Virulence. 0.588888889. PubMed
  81. Shin J, et al. 2018. Diabetes. 67:1068. PubMed
  82. Khan KA, et al. 2020. NPJ Breast Cancer. 6:29. PubMed
  83. Feng L, et al. 2019. Glia. 67:1434. PubMed
  84. Kang SH, et al. 2018. Oncoimmunology. 8:e1515057. PubMed
  85. Chen L, et al. 2019. Nat Commun. 3.553472222. PubMed
  86. Taki M, et al. 2018. Nat Commun. 1.545138889. PubMed
  87. Arnold IC, et al. 2018. J Exp Med. 215:2055. PubMed
  88. Majer O, et al. 2019. Nature. 575:366. PubMed
  89. Guiducci E, et al. 2018. Front Immunol. 1.467361111. PubMed
  90. Vinaik R, et al. 2019. Am J Physiol Endocrinol Metab. 317:E751. PubMed
  91. Olver S, et al. 2005. Cancer Res. 66:571. PubMed
  92. Elgazar-Carmon V, et al. 2008. J Lipid Res. 49:1849. PubMed
  93. Guo Y, et al. 2008. Blood. 112:480. PubMed
  94. Kim D, et al. 2008. Blood. 112:1109. PubMed
  95. Napimoga M, et al. 2008. J Immunol. 180:609. PubMed
  96. Baumgartner C, et al. 2010. J Immunol. 184:573. PubMed
  97. Ashok A, et al. 2015. Toxicol Sci. 143:64. PubMed
  98. Sun Y, et al. 2015. Proc Natl Acad Sci U S A. 112: 10401-10406. PubMed
  99. Peng J, et al. 2016. Nat Commun. 7:12029. PubMed
  100. Rossnagl S, et al. 2016. PLoS Biol. 14: 1002562. PubMed
  101. Francis M, et al. 2017. Toxicol Sci. 155(1):182-195. PubMed
  102. Galbas T, et al. 2017. J Immunol. 198(2):852-861. PubMed
  103. Zareie P, et al. 2017. J Neuroinflammation. 0.630555556. PubMed
  104. Coden ME, et al. 2020. J Immunol. 204:438. PubMed
  105. Weidner H, et al. 2020. JCI Insight. 5:00. PubMed
  106. Huang S, et al. 2020. Cell Rep. 33:108394. PubMed
  107. Li X, et al. 2020. J Clin Invest. 130:4182. PubMed
  108. Karhadkar TR, et al. 2021. PLoS One. 16:e0245924. PubMed
  109. Tal MC, et al. 2020. MBio. 11:00. PubMed
  110. Nicolas-Boluda A, et al. 2021. eLife. 10:00. PubMed
  111. Chevrier S, et al. 2021. Cell Reports Medicine. 2(1):100166. PubMed
  112. Heib T, et al. 2021. Cell Reports. 35(6):109102. PubMed
  113. Hsieh YL, et al. 2019. Cell Reports. 29(8):2134-2143.e7. PubMed
  114. Reglero-Real N, et al. 2021. Immunity. :. PubMed
  115. Aikawa S, et al. 2020. Cell Death Differ. 1489:27. PubMed
  116. Karuppuchamy T, et al. 2020. Inflamm Bowel Dis. 216:26. PubMed
  117. Zhong X, et al. 2020. Proc Natl Acad Sci U S A. 8563:117. PubMed
  118. Karhadkar TR, et al. 2020. bioRxiv. . PubMed
  119. Yi MH, et al. 2020. Brain Behav Immun. 92:78. PubMed
  120. Zheng C, et al. 2021. J Extracell Vesicles. 10:e12109. PubMed
  121. Gui J, et al. 2020. Nat Cancer. 1:603. PubMed
  122. Si Y, et al. 2020. Sci Adv. 6:eaaw7713. PubMed
  123. Lai JF, et al. 2020. J Allergy Clin Immunol. 146:1406. PubMed
  124. Khan KA, et al. 2020. NPJ Breast Cancer. 6:29. PubMed
  125. Murenu E, et al. 2021. Int J Mol Sci. 22:. PubMed
  126. Murenu E, et al. 2021. Mol Ther Methods Clin Dev. 20:587. PubMed
  127. Vukman KV, et al. 2020. J Extracell Vesicles. 10:e12023. PubMed
  128. Larson-Casey JL, et al. 2021. FASEB J. 35:e21675. PubMed
  129. Zhao J, et al. 2021. JCI Insight. 6:. PubMed
  130. Hutton C, et al. 2021. Cancer Cell. 39:1227. PubMed
  131. Chen HW, et al. 2021. Biomedicines. 9:. PubMed
  132. Rogic A, et al. 2021. Nat Commun. 12:6889. PubMed
  133. Freeman SA, et al. 2020. Science. 367:301. PubMed
  134. O'Dea KP, et al. 2020. J Extracell Vesicles. 9:1706708. PubMed
  135. Kikuchi A, et al. 2020. Am J Pathol. 190:2080. PubMed
  136. Karhadkar TR, et al. 2021. J Pharmacol Exp Ther. 376:106. PubMed
  137. Kobayashi A, et al. 2021. Front Immunol. 12:650856. PubMed
  138. Matsuhira T, et al. 2021. Biochem Biophys Rep. 28:101118. PubMed
  139. Takeuchi Y, et al. 2021. Sci Rep. 11:18679. PubMed
  140. Nguyen N, et al. 2022. iScience. 25:103679. PubMed
  141. Jiang L, et al. 2022. Front Immunol. 12:730438. PubMed
  142. Bredehöft J, et al. 2022. J Inflamm Res. 15:509. PubMed
  143. Krueger A, et al. 2022. Front Microbiol. 12:789042. PubMed
  144. Ding L, et al. 2022. Nanoscale. . PubMed
  145. Prabakaran T, et al. 2021. EBioMedicine. 66:103314. PubMed
  146. Scortegagna M, et al. 2020. Nat Commun. 11:99. PubMed
  147. Johnson SA, et al. 2021. Eur J Immunol. 51:3228. PubMed
  148. Paterson MJ, et al. 2020. PLoS Pathog. 16:e1008733. PubMed
  149. Speir M, et al. 2020. Nat Immunol. 21:54. PubMed
  150. Dienz O, et al. 2020. J Immunol. 204:1521. PubMed
  151. Hakamivala A, et al. 2020. Bioact Mater. 5:142. PubMed
  152. Lin Z, et al. 2021. Stem Cells. 39:240. PubMed
  153. Song M, et al. 2020. Nat Commun. 11:6298. PubMed
  154. Link CWM, et al. 2020. Front Immunol. 11:596772. PubMed
  155. Bajaña S, et al. 2021. Front Immunol. 11:577718. PubMed
  156. Mohrin M, et al. 2021. Aging Cell. 20:e13313. PubMed
  157. Li Y, et al. 2021. Life Sci Alliance. 4:. PubMed
  158. Wen J, et al. 2021. PLoS Pathog. 17:e1009738. PubMed
  159. Suzuki Y, et al. 2021. FEBS Open Bio. 11:2619. PubMed
  160. Manabe T, et al. 2021. J Neurochem. 159:525. PubMed
  161. Flores I, et al. 2021. Hum Mol Genet. Online ahead of print. PubMed
  162. Seo SU, et al. 2021. Front Immunol. 12:697162. PubMed
  163. Qiu Z, et al. 2022. Cancer Discov. 12:502. PubMed
  164. Sato Y, et al. 2021. BMC Cancer. 21:1222. PubMed
  165. Prado C, et al. 2021. J Neuroinflammation. 18:292. PubMed
  166. Sun Y, et al. 2022. Nat Commun. 13:3916. PubMed
  167. Meyer-Lindemann U, et al. 2022. Front Immunol. 13:898690. PubMed
  168. Vahsen BF, et al. 2022. Sci Rep. 12:12606. PubMed
  169. Pilling D, et al. 2022. Respir Res. 23:215. PubMed
  170. Dertschnig S, et al. 2020. J Clin Invest. 130:1896. PubMed
  171. Tian D, et al. 2020. FASEB J. 34:3367. PubMed
  172. Yan J, et al. 2020. Cancer Immunol Res. 8:356. PubMed
  173. Schuler CF, et al. 2020. Allergy. 75:2279. PubMed
  174. Tsukui H, et al. 2020. BMC Cancer. 20:411. PubMed
  175. Leyva-Castillo JM, et al. 2020. Clin Immunol. 218:108511. PubMed
  176. Lim CS, et al. 2020. Front Immunol. 11:1186. PubMed
  177. Wu W, et al. 2020. Brain Behav Immun. 89:245. PubMed
  178. Stotesbury C, et al. 2020. Aging Cell. 19:e13170. PubMed
  179. Liu H, et al. 2020. J Immunol. 205:1207. PubMed
  180. Gomi M, et al. 2021. Mol Ther. 29:225. PubMed
  181. Nguyen CH, et al. 2020. Biomedicines. 8:. PubMed
  182. Muraleedharan A, et al. 2021. Glia. 69:697. PubMed
  183. Chen L, et al. 2020. Front Immunol. 11:584458. PubMed
  184. Yoon S, et al. 2020. Antioxidants (Basel). 10:. PubMed
  185. Kästele V, et al. 2021. Mucosal Immunol. 14:717. PubMed
  186. Brownlie D, et al. 2021. J Immunother Cancer. 9:. PubMed
  187. Cané S, et al. 2021. J Immunother Cancer. 9:. PubMed
  188. Delgobo M, et al. 2021. Front Immunol. 12:584538. PubMed
  189. He LD, et al. 2021. EMBO Rep. 22:e52196. PubMed
  190. Tao H, et al. 2021. Front Immunol. 12:623280. PubMed
  191. Bednarczyk M, et al. 2021. Int J Mol Sci. 22:. PubMed
  192. Shokirova H, et al. 2021. Sci Rep. 11:8647. PubMed
  193. Brown IK, et al. 2021. PLoS Pathog. 17:e1009602. PubMed
  194. Udumula MP, et al. 2021. Mol Metab. 53:101272. PubMed
  195. Dubik M, et al. 2021. Front Neurosci. 15:682451. PubMed
  196. Li J, et al. 2021. Front Immunol. 12:710406. PubMed
  197. Stefanescu C, et al. 2021. Front Oncol. 11:765151. PubMed
  198. You X, et al. 2022. Front Genet. 12:790990. PubMed
  199. Lee JH, et al. 2022. iScience. 25:104166. PubMed
  200. Yonemitsu K, et al. 2022. Sci Rep. 12:12007. PubMed
  201. Düking T, et al. 2022. Sci Adv. 8:eabo7639. PubMed
  202. Li F, et al. 2020. EMBO J. 39:e103205. PubMed
  203. Liu CJ, et al. 2020. Neuro Oncol. 22:1276. PubMed
  204. Doll JR, et al. 2020. PLoS Pathog. 16:e1008296. PubMed
  205. Yu H, et al. 2020. Front Immunol. 11:1773. PubMed
  206. Cai S, et al. 2020. Sci Rep. 10:14249. PubMed
  207. Calcagno DM, et al. 2020. Sci Immunol. 5: . PubMed
  208. Malinczak CA, et al. 2021. J Immunol. 206:1315. PubMed
  209. Li H, et al. 2022. Cancer Cell. 40:36. PubMed
  210. Moore J, et al. 2022. Cancer Res. 82:365. PubMed
  211. Valet C, et al. 2022. J Clin Invest. 132: . PubMed
  212. Xiong T, et al. 2022. Cancer Sci. 113:1955. PubMed
  213. Campisi L, et al. 2022. Nature. 606:945. PubMed
  214. Moore AR, et al. 2022. Cell Rep. 41:111651. PubMed
  215. Zhao J, et al. 2022. J Clin Invest. 132: . PubMed
  216. Gavish A, et al. 2023. iScience. 26:105826. PubMed
  217. Jiang L, et al. 2021. Nano Today. 36:. PubMed
  218. Potempa M, et al. 2022. J Immunol. 208:1742. PubMed
  219. Shirai T, et al. 2022. Cancer Sci. 113:3710. PubMed
  220. Chen W, et al. 2023. JCI Insight. 8:. PubMed
  221. Wang JX, et al. 2023. JCI Insight. 8:. PubMed
  222. Kang YA, et al. 2023. J Exp Med. 220:. PubMed
  223. Diray-Arce J, et al. 2023. Cell Rep Med. 4:101079. PubMed
RRID
AB_312784 (BioLegend Cat. No. 101201)
AB_312785 (BioLegend Cat. No. 101202)

Antigen Details

Structure
Integrin family, associates with integrin β2 (CD18), 170 kD
Distribution

Granulocytes, monocytes/macrophages, dendritic cells, NK cells, subsets of T and B cells

Function
Adhesion, chemotaxis
Ligand/Receptor
ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, fibrinogen
Cell Type
B cells, Dendritic cells, Granulocytes, Macrophages, Monocytes, Neutrophils, NK cells, T cells, Tregs
Biology Area
Cell Adhesion, Cell Biology, Costimulatory Molecules, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Springer TA. 1994. Cell 76:301.
3. Coxon A, et al. 1996. Immunity 5:653.

Gene ID
16409 View all products for this Gene ID 3684 View all products for this Gene ID
UniProt
View information about CD11b on UniProt.org
Go To Top Version: 4    Revision Date: 12.13.2019

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

ProductsHere
Login / Register
Remember me
Forgot your password? Reset password?
Create an Account