- Clone
- 2/40/15 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Tyrosine 3-monooxygenase, tyrosine 3-hydroxylase
- Previously
-
Covance Catalog# MMS-5210, MMS-5210-100, MMS5210
- Isotype
- Mouse IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
818002 | 25 µL | £73 | ||||
818001 | 100 µL | £189 |
Tyrosine hydroxylase, also known as tyrosine 3-monooxygenase, is the enzyme that converts amino acid L-Tyrosine to L-3, 4-Dihydroxyphenylalanine (L-DOPA). L-DOPA is a precursor to dopamine, which is then converted to norepinephrine and epinephrine (adrenaline). Dopamine, norepinephrine and epinephrine are all important neurotransmitters. Alterations in the activity of tyrosine hydroxylase may be involved in a number of neurological diseases such as Parkinson's and schizophrenia.
Product DetailsProduct Details
- Verified Reactivity
- Human, Mouse, Rat
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- This monoclonal antibody was raised against purified Tyrosine Hydroxylase from rat Pheochromocytoma tumor.
- Formulation
- Phosphate-buffered solution.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 1.0 mg/ml
- Storage & Handling
- This antibody should be handled aseptically as it is free of preservatives such as Sodium Azide. Store this antibody undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check the vial label or CoA to find the proper storage conditions.
- Application
-
IHC-P - Quality tested
WB - Verified - Recommended Usage
-
Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 0.5 - 1.0 µg/ml is suggested. For Western blotting, the suggested use of this reagent is 1.0 - 10.0 µg per ml. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
-
This antibody is effective in immunoblotting (WB) and formalin-fixed paraffin-embedded immunohistochemical staining (IHC-P).
This antibody is less reactive in human tissue in Western Blot. - Product Citations
-
- RRID
-
AB_2734573 (BioLegend Cat. No. 818002)
AB_2564816 (BioLegend Cat. No. 818001)
Antigen Details
- Structure
- Expected MW: 65 kD
- Cell Type
- Dopaminergic Neurons, Neural Stem Cells, Neurons
- Biology Area
- Cell Biology, Neuroscience, Neuroscience Cell Markers, Stem Cells, Synaptic Biology
- Molecular Family
- Enzymes and Regulators, Presynaptic proteins
- Gene ID
- 25085 View all products for this Gene ID
- Specificity (DOES NOT SHOW ON TDS):
- Tyrosine Hydroxylase
- Specificity Alt (DOES NOT SHOW ON TDS):
- Tyrosine Hydroxylase
- App Abbreviation (DOES NOT SHOW ON TDS):
- IHC-P,WB
- UniProt
- View information about Tyrosine Hydroxylase on UniProt.org
Related FAQs
Other Formats
View All Tyrosine Hydroxylase Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-Tyrosine Hydroxylase | 2/40/15 | IHC-P,WB |
Alexa Fluor® 594 anti-Tyrosine Hydroxylase | 2/40/15 | IHC-P |
Alexa Fluor® 647 anti-Tyrosine Hydroxylase | 2/40/15 | IHC-P |
Alexa Fluor® 488 anti-Tyrosine Hydroxylase | 2/40/15 | IHC-P |
Spark YG™ 570 anti-Tyrosine Hydroxylase | 2/40/15 | IHC-P |
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-Tyrosine Hydroxylase
IHC staining of purified anti-Tyrosine Hydroxylase antibody ... IHC staining of purified anti-Tyrosine Hydroxylase antibody ... IHC staining of purified anti-Tyrosine Hydroxylase antibody ... IHC staining of purified anti-Tyrosine Hydroxylase antibody... IHC staining of purified anti-Tyrosine Hydroxylase antibody ... Western blot of purified anti-Tyrosine Hydroxylase antibody ... -
Alexa Fluor® 594 anti-Tyrosine Hydroxylase
IHC staining of Alexa Fluor® 594 anti-Tyrosine Hydroxylase a... IHC staining of Alexa Fluor® 594 anti-Tyrosine Hydroxylase a... IHC staining of Alexa Fluor® 594 anti-Tyrosine Hydroxylase a... -
Alexa Fluor® 647 anti-Tyrosine Hydroxylase
IHC staining of Alexa Fluor® 647 anti-Tyrosine Hydroxylase a... IHC staining of Alexa Fluor® 647 anti-Tyrosine Hydroxylase a... IHC staining of Alexa Fluor® 647 anti-Tyrosine Hydroxylase a... IHC staining of Alexa Fluor® 647 anti-Tyrosine Hydroxylase a... -
Alexa Fluor® 488 anti-Tyrosine Hydroxylase
IHC staining of Alexa Fluor® 488 anti-Tyrosine Hydroxylase a... IHC staining of Alexa Fluor® 488 anti-Tyrosine Hydroxylase a... IHC staining of Alexa Fluor® 488 anti-Tyrosine Hydroxylase a... -
Spark YG™ 570 anti-Tyrosine Hydroxylase
IHC staining of Spark YG™ 570 anti-Tyrosine Hydroxylase anti... IHC staining of Spark YG™ 570 anti-Tyrosine Hydroxylase anti...
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