- Clone
- QA19A43 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Hermes, Pgp1, H-CAM, or HUTCH
- Isotype
- Rat IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
![QA19A43_FITC_CD44_RECOM_Antibody_090121.png QA19A43_FITC_CD44_RECOM_Antibody_090121.png](https://d1spbj2x7qk4bg.cloudfront.net/Admin/Public/GetImage.ashx?Image=/Files/Images/media_assets/products/product_images/QA19A43_FITC_CD44_RECOM_Antibody_090121.png&Width=240&Height=300&altFmImage_path=&Compression=90&Crop=5)
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C57BL/6 splenocytes were stained with anti-mouse/human CD44 recombinant (clone QA19A43) FITC (filled histogram) or rat IgG2a, κ FITC isotype control (open histogram).
Cat # | Size | Price | Quantity Check Availability | Save | ||
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163605 | 25 µg | £57 | ||||
163606 | 100 µg | £129 |
CD44 is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. It has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.
Product DetailsProduct Details
- Verified Reactivity
- Mouse, Human
- Antibody Type
- Recombinant
- Host Species
- Rat
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
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FC - Quality tested
- Recommended Usage
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Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Product Citations
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- RRID
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AB_2894435 (BioLegend Cat. No. 163605)
AB_2894435 (BioLegend Cat. No. 163606)
Antigen Details
- Structure
- Variable splicing of CD44 gene generates many CD44 isoforms, 80-95 kD
- Distribution
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All leukocytes, epithelial cells, endothelial cells, hepatocytes, mesenchymal cells.
- Function
- Leukocyte attachment and rolling on endothelial cells, stromal cells and ECM.
- Ligand/Receptor
- Hyaluronan, MIP-1β, fibronectin, collagen.
- Antigen References
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- Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
- Haynes BF, et al. 1991. Cancer Cells. 3:347.
- Goldstein LA, et al. 1989. Cell. 56:1063.
- Mikecz K, et al. 1995. Nat Med. 1:558.
- Hegde V, et al. 2008. J Leukocyte Biol. 84:134.
- Liu T, et al. 2009. Biol Direct. 4:40.
- Gene ID
- 12505 View all products for this Gene ID
- UniProt
- View information about CD44 on UniProt.org
Related Pages & Pathways
Pages
Other Formats
View All CD44 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-mouse/human CD44 Recombinant Antibody | QA19A43 | FC |
PE/Cyanine7 anti-mouse/human CD44 Recombinant | QA19A43 | FC |
APC anti-mouse/human CD44 Recombinant Antibody | QA19A43 | FC |
FITC anti-mouse/human CD44 Recombinant Antibody | QA19A43 | FC |
PE anti-mouse/human CD44 Recombinant Antibody | QA19A43 | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-mouse/human CD44 Recombinant Antibody
C57BL/6 mouse splenocytes were stained with purified anti-mo... -
PE/Cyanine7 anti-mouse/human CD44 Recombinant
C57BL/6 splenocytes were stained with anti-mouse/human CD44 ... -
APC anti-mouse/human CD44 Recombinant Antibody
C57BL/6 splenocytes were stained with anti-mouse/human CD44 ... -
FITC anti-mouse/human CD44 Recombinant Antibody
C57BL/6 splenocytes were stained with anti-mouse/human CD44 ... -
PE anti-mouse/human CD44 Recombinant Antibody
C57BL/6 splenocytes were stained with anti-mouse/human CD44 ...
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