- Clone
- 7B7/FcRL6 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- FcRL6, Fc receptor like 6
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
![7B7slashFcRL6_PURe_FcRL6_Antibody_1_040717 7B7slashFcRL6_PURe_FcRL6_Antibody_1_040717](https://d1spbj2x7qk4bg.cloudfront.net/Admin/Public/GetImage.ashx?Image=/Files/Images/media_assets/products/product_images/7B7slashFcRL6_PURe_FcRL6_Antibody_1_040717.jpg&Width=240&Height=300&altFmImage_path=&Compression=90&Crop=5)
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Human peripheral blood lymphocytes were stained with CD56 Alexa Fluor® 647 and FcRL6 (clone 7B7/FcRL6) Purified (top) or mouse Ig1, κ Purified isotype control (bottom), followed by anti-mouse IgG1 PE. -
Cat # | Size | Price | Quantity Check Availability | Save | ||
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373902 | 100 µg | £141 |
FcRL6, a member of Fc receptor-like family, does not bind Ig. It is expressed on cytotoxic NK and a subset of T cells (primarily CD8+ T cells). Its expression level correlates with the differentiation state of these cells. This Type I transmembrane glycoprotein consists of three Ig-like domains on its extracellular and a consensus ITIM or non-canonical ITAM-like sequence on its cytoplasmic region. Patients with chronic lymphocytic leukemia show higher abundance of this receptor due to expansion of cytotoxic lymphocyte population.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- BW5147 transduced with HA-tagged FcRL6
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
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FC - Quality tested
- Recommended Usage
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Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
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Application References
(PubMed link indicates BioLegend citation) -
- Schreeder DM, et al. 2008. Eur. J. Immunol. 38:3159. (FC)
- RRID
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AB_2687026 (BioLegend Cat. No. 373902)
- Disclaimer
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This clone is listed under the following US Patent Numbers: 7,317,087 & 8,648,171.
Antigen Details
- Structure
- Type I transmembrane glycoprotein, Ig gene superfamily
- Distribution
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NK, T subset
- Cell Type
- NK cells, T cells
- Biology Area
- Immunology
- Molecular Family
- Fc Receptors
- Antigen References
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1. Davis RS. 2007. Annu. Rev. Immunol. 25:525.
2. Wilson TJ, et al. 2007. Blood 109:3786.
3. Schreeder DM, et al. 2008. 38:3159. - Gene ID
- 343413 View all products for this Gene ID
- UniProt
- View information about FcRL6 on UniProt.org
Related Pages & Pathways
Pages
Related FAQs
Other Formats
View All FcRL6 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-human FcRL6 | 7B7/FcRL6 | FC |
APC anti-human FcRL6 | 7B7/FcRL6 | FC |
PE anti-human FcRL6 | 7B7/FcRL6 | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human FcRL6
Human peripheral blood lymphocytes were stained with CD56 Al... -
APC anti-human FcRL6
Human peripheral blood lymphocytes were stained with anti-hu... -
PE anti-human FcRL6
Human peripheral blood lymphocytes were stained with anti-hu...
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