Purified anti-mouse CD138 (Syndecan-1) Antibody

Pricing & Availability
Clone
W20051E (See other available formats)
Regulatory Status
RUO
Other Names
Syndecan-1, Sdc1
Isotype
Rat IgG2b, κ
Ave. Rating
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Product Citations
publications
W20051E_Purified_CD138_Antibody_042423
C57BL/6 mouse bone marrow cells were stained with purified anti-mouse CD138 (Syndecan-1) (clone W20051E) (left) or with purified rat IgG2b, κ isotype control (right), then with anti-rat IgG PE. Cells were then costained with anti-mouse CD19 APC. Data shown is gated on lymphoid cell population.
  • W20051E_Purified_CD138_Antibody_042423
    C57BL/6 mouse bone marrow cells were stained with purified anti-mouse CD138 (Syndecan-1) (clone W20051E) (left) or with purified rat IgG2b, κ isotype control (right), then with anti-rat IgG PE. Cells were then costained with anti-mouse CD19 APC. Data shown is gated on lymphoid cell population.
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112502 100 µg £69
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Description

CD138, a member of the syndecan protein family, is a type I integral membrane heparin sulfate proteoglycan also known as Syndecan-1. Syndecan-1 participates in cell proliferation, cell migration, and cell matrix adhesion via interaction with collagen, fibronectin, and other soluble molecules (such as FGF-basic). It is expressed on normal and malignant plasma cells, pre-B cells, mesenchymal cells, epithelial cells, and endothelial cells.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Mouse syndecan-1-transfected cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2941390 (BioLegend Cat. No. 112502)

Antigen Details

Structure
Transmembrane heparan sulfate proteoglycan; member of the syndecan proteoglycan family, 100-200 kD
Distribution

Malignant plasma cells, pre-B cells, mesenchymal cells, epithelial cells, and endothelial cells

Function
Cell adhesion, cell motility, cell migration, cell proliferation
Ligand/Receptor
Collagen, fibronectin
Cell Type
B cells
Biology Area
Apoptosis/Tumor Suppressors/Cell Death, Cell Adhesion, Cell Biology, Cell Motility/Cytoskeleton/Structure, Immunology
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References
  1. Zong F, et al. 2011. PLoS ONE. 6:e14816.
  2. Yamashita Y, et al. 1999. J Immunol. 162:5940-8.
  3. Sanderson RD, et al. 1989. Cell Regul. 1:181-5. 
  4. Szatmari T, et al. 2013. Front Oncol. 13:310.
Gene ID
20969 View all products for this Gene ID
UniProt
View information about CD138 on UniProt.org
Go To Top Version: 1    Revision Date: 03/20/2023

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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