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- Clone
- 17-206.RecM1 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Blood group antigen H (type 1)
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
IHC staining of Purified anti-BG-4 Recombinant (clone 17-206.RecM1) on formalin-fixed paraffin-embedded human antrum (stomach) tissue. The tissue was incubated with primary antibody overnight at 4°C. BioLegend’s Ultra Streptavidin HRP Kit (Multi-Species, DAB, Cat. No. 929501) was used for detection followed by hematoxylin counterstaining. The images were captured using a 10X (panel A) and 40X (panel B) objective. Scale bar: 50 µm
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 667551 | 25 µg | 144€ | ||||
| 667552 | 100 µg | 352€ | ||||
BG-4, also known as blood group antigen H (type 1), is a carbohydrate sequence linked to a protein or ceramide. BG-4 is a precursor to the A and B antigens in the ABO system. For individuals with O type blood, the BG-4 antigen remains unmodified. BG-4 formation is catalyzed by the fucosyltransferase 1 enzyme (FUT1). BG-4 is expressed on erythrocytes and epithelial cells, and is thought to play a role in immune response, cell-cell recognition, and in the structural integrity of cells.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Recombinant
- Host Species
- Mouse
- Immunogen
- This antibody was developed against the SW-403 colon cancer cell line. It is specific for Blood group H (type 1).
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
IHC-P - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 1.0 - 10.0 µg/mL is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
-
With this antibody no antigen retrieval is required.
Antigen Details
- Structure
- BG-4 is a carbohydrate sequence consisting of a chain of β-D-galactose, β-D-N-acetylglucosamine, β-D-galactose, and 2-linked, α-L-fucose
- Distribution
-
Cytoplasmic, cell surface
- Function
- Cell surface antigen, structural
- Cell Type
- Granulocytes, Macrophages, Monocytes, Neutrophils
- Biology Area
- Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience
- Molecular Family
- CD Molecules
- Antigen References
-
- Lloyd KO, et al. 1983. Immunogen. 17:537.
- Sakamoto J, et al. 1984. Mol Immunol. 21:1093.
- Anger BR, et al. 1982. Hybridoma. 1:139.
- Gene ID
- NA
- UniProt
- View information about BG-4 on UniProt.org
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