Purified anti-human CD41b Antibody

Pricing & Availability
Clone
HIP2 (See other available formats)
Regulatory Status
RUO
Workshop
HCDM listed
Other Names
ITGA2B, Integrin alpha-IIb, Platelet membrane glycoprotein IIb, GPalpha IIb, CD41
Isotype
Mouse IgG3, κ
Ave. Rating
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Product Citations
publications
HIP2_Pure_060812
Human peripheral blood platelets stained with purified CD41b (clone HIP2) (filled histogram) or mouse IgG3, followed by anti-mouse IgG FITC.
  • HIP2_Pure_060812
    Human peripheral blood platelets stained with purified CD41b (clone HIP2) (filled histogram) or mouse IgG3, followed by anti-mouse IgG FITC.
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354802 100 µg 104€
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Description

CD41b is a β chain of glycoprotein IIb (known as CD41) which is associated with glycoprotein IIIa (or integrin β3, CD61) and forms CD41/CD61 complex. CD41/CD61 mediates platelet adhesion and aggregation through the interaction with fibrinogen, fibronectin, von Willebrand factor, and thrombin. CD41 is expressed by platelets and megakaryocytes.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤2.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application References
  1. Leong L, et al. 1995. J. Cell. Sci. 108:3817.
RRID
AB_11218799 (BioLegend Cat. No. 354802)

Antigen Details

Structure
A β chain of glycoprotein IIb that associates with glycoprotein IIIa to form a CD41/CD61 complex
Distribution

Platelets, Megakaryocytes

Function
Platelet activation and aggregation
Cell Type
Platelets, Megakaryocytes
Biology Area
Angiogenesis, Cell Biology, Immunology
Molecular Family
Adhesion Molecules, CD Molecules, Protein Kinases/Phosphatase
Antigen References

1. Nakahata T, et al. 1994 Leuk. Lymphoma 13:401.

Gene ID
3674 View all products for this Gene ID
UniProt
View information about CD41b on UniProt.org
Go To Top Version: 1    Revision Date: 11/30/2012

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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