- Clone
- S20011B (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Integrin alpha V beta 8
- Isotype
- Rat IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
![S20011B_PURE_integrin-aVB8_Antibody_1_092723 S20011B_PURE_integrin-aVB8_Antibody_1_092723](https://d1spbj2x7qk4bg.cloudfront.net/Admin/Public/GetImage.ashx?Image=/Files/Images/media_assets/products/product_images/S20011B_PURE_integrin-aVB8_Antibody_1_092723.png&Width=240&Height=300&altFmImage_path=&Compression=90&Crop=5)
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Mouse integrin αVβ8 transfected Ba/F3 cells were stained with purified anti-mouse Integrin αVβ8 (clone S20011B) (filled histogram) or purified rat IgG1, κ isotype control (open histogram) followed by PE goat anti-rat IgG.
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
114802 | 100 µg | 278€ |
Integrins are heterodimeric transmembrane receptors that mediate cell-cell and cell-extracellular matrix adhesion. Integrin αVβ8 is also involved in TGF-β activation, which contributes to regulatory T cell (Treg) activities.
Product DetailsProduct Details
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Mouse αVβ8 integrin-transfected cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
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Clone S20011B does not affect the binding of clone S20011E on target cells.
Clone S20011B does not react with mouse integrin αVβ6.
Antigen Details
- Structure
- Integrins
- Distribution
-
Epithelial cells
- Function
- Cell adhesion, TGF-β activation
- Cell Type
- Epithelial cells, Tregs
- Biology Area
- Cell Adhesion, Cell Biology, Immuno-Oncology, Immunology
- Molecular Family
- Adhesion Molecules
- Antigen References
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- Moyle M, et al. 1991. J Biol Chem. 266:19650-8
- Gene ID
- 16410 View all products for this Gene ID 320910 View all products for this Gene ID
- UniProt
- View information about Integrin alphaVbeta8 on UniProt.org
Related FAQs
Other Formats
View All Integrin αVβ8 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-mouse Integrin αVβ8 | S20011B | FC |
FITC anti-mouse Integrin αVβ8 | S20011B | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-mouse Integrin αVβ8
Mouse integrin αVβ8 transfected Ba/F3 cells were stained wit... -
FITC anti-mouse Integrin αVβ8
Mouse integrin αVβ8 transfected Ba/F3 cells were stained wit...
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