- Clone
- J034D6 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Interferon gamma induced protein-10 (IP-10)
- Isotype
- Mouse IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
![J034D6_APC_CXCL10_IP-10_Antibody_101221_1 J034D6_APC_CXCL10_IP-10_Antibody_101221_1](https://d1spbj2x7qk4bg.cloudfront.net/Admin/Public/GetImage.ashx?Image=/Files/Images/media_assets/products/product_images/J034D6_APC_CXCL10_IP-10_Antibody_101221_1.png&Width=240&Height=300&altFmImage_path=&Compression=90&Crop=5)
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Human peripheral blood monocytes were stimulated with IFN-γ (1500U/mL) for 24 hours (in the presence of monensin). Cells were stained with CD14 PE then fixed and permeabilized. Cells were then stained with CXCL10 (IP-10) (clone J034D6) APC (left) or mouse IgG2a, κ APC isotype control (right).
Cat # | Size | Price | Quantity Check Availability | Save | ||
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519505 | 25 tests | $154 | ||||
519506 | 100 tests | $332 |
CXCL10, also known as IP-10, is a 8.7 kD chemokine. It belongs to the CXC chemokine family. It is expressed by monocytes, fibroblasts, and endothelial cells in response to IFNγ. It can interact with CXCR3 and plays an important role in immune cell trafficking, particularly of T cells, dendritic cells, and NK cells. In addition, it alters expression of adhesion molecules.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Reported Reactivity
- Rhesus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
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ICFC - Quality tested
- Recommended Usage
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Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
-
Red Laser (633 nm)
- RRID
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AB_2904431 (BioLegend Cat. No. 519505)
AB_2904431 (BioLegend Cat. No. 519506)
Antigen Details
- Structure
- CXC chemokine family, 8.7 kD
- Distribution
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Monocytes, endothelial cells, and fibroblasts
- Function
- Interacts with CXCR3 and serves as a chemoattractant for T cells, dendritic cells, monocytes/macrophages, and NK cells
- Ligand/Receptor
- CXCR3
- Cell Type
- B cells, Dendritic cells, Endothelial cells, Fibroblasts, Monocytes
- Biology Area
- Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience
- Molecular Family
- Cytokines/Chemokines
- Antigen References
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1. Luster AD, et al. 1987. Proc. Natl. Acad. Sci. USA 84:2868.
2. Kaplan G, et al. 1987. J. Exp. Med. 166:1098.
3. Sarris AH, et al. 1993. J. Exp. Med. 178:1127. - Gene ID
- 3627 View all products for this Gene ID
- UniProt
- View information about CXCL10 on UniProt.org
Other Formats
View All CXCL10 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-human CXCL10 (IP-10) | J034D6 | ICFC,WB |
PE anti-human CXCL10 (IP-10) | J034D6 | ICFC |
APC anti-human CXCL10 (IP-10) Antibody | J034D6 | ICFC |
PE/Cyanine7 anti-human CXCL10 (IP-10) Antibody | J034D6 | ICFC |
PerCP/Cyanine5.5 anti-human CXCL10 (IP-10) | J034D6 | ICFC |
TotalSeq™-B1207 anti-human CXCL10 (IP-10) | J034D6 | ICPG |
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human CXCL10 (IP-10)
IFN-γ (1500U/ml)-stimulated (24 hours) human peripheral bloo... -
PE anti-human CXCL10 (IP-10)
Human peripheral blood monocytes were stimulated with IFN-&g... -
APC anti-human CXCL10 (IP-10) Antibody
Human peripheral blood monocytes were stimulated with IFN-γ ... -
PE/Cyanine7 anti-human CXCL10 (IP-10) Antibody
Human peripheral blood monocytes were stimulated with IFN-γ ... -
PerCP/Cyanine5.5 anti-human CXCL10 (IP-10)
Human peripheral blood monocytes were stimulated with IFN-γ ... -
TotalSeq™-B1207 anti-human CXCL10 (IP-10)
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