- Clone
- S16020B (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Interleukin-12 receptor subunit beta-2
- Isotype
- Mouse IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
![S16020B_BV421_IL12RB2_Antibody_051922 S16020B_BV421_IL12RB2_Antibody_051922](https://d1spbj2x7qk4bg.cloudfront.net/Admin/Public/GetImage.ashx?Image=/Files/Images/media_assets/products/product_images/S16020B_BV421_IL12RB2_Antibody_051922-.png&Width=240&Height=300&altFmImage_path=&Compression=90&Crop=5)
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Human peripheral blood lymphocytes were activated for 3 days with anti-human CD3 and anti-human CD28, and then stained with anti-human IL12RB2 (clone S16020B) Brilliant Violet 421™ (filled histogram) or mouse IgG2a, κ Brilliant Violet 421™ isotype control (open histogram).
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
394211 | 25 tests | $193 | ||||
394212 | 100 tests | $407 |
IL12RB2 is a type I transmembrane protein that foms an heterodimer with IL12RB1 to produce the high affinity IL-12 receptor complex. IL12RB2 is expressed by activated T cells, TH1 cells, NK cells, B cells and plasma cells. Variants of this gene are associated with predisposition to various immune-related diseases.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human IL12RB2 transfected cells.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with Brilliant Violet 421™ under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Brilliant Violet 421™ excites at 405 nm and emits at 421 nm. The standard bandpass filter 450/50 nm is recommended for detection. Brilliant Violet 421™ is a trademark of Sirigen Group Ltd.
Learn more about Brilliant Violet™.
This product is subject to proprietary rights of Sirigen Inc. and is made and sold under license from Sirigen Inc. The purchase of this product conveys to the buyer a non-transferable right to use the purchased product for research purposes only. This product may not be resold or incorporated in any manner into another product for resale. Any use for therapeutics or diagnostics is strictly prohibited. This product is covered by U.S. Patent(s), pending patent applications and foreign equivalents. - Excitation Laser
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Violet Laser (405 nm)
- RRID
-
AB_2922619 (BioLegend Cat. No. 394211)
AB_2922619 (BioLegend Cat. No. 394212)
Antigen Details
- Structure
- Type I transmembrane protein, 3 isoforms, foms an heterodimer with IL12RB1
- Distribution
-
Activated T cells, TH1 cells, NK cells, B cells, plasma cells
- Function
- Role in TH1 differentiation
- Ligand/Receptor
- IL-12
- Cell Type
- B cells, NK cells, Plasma cells, T cells, Th1
- Biology Area
- Immunology
- Molecular Family
- Cytokine/Chemokine Receptors
- Antigen References
-
- LaMere SA, et al. 2017. J Immunol. 199:3158
- Prigione I, et al. 2016. Immunobiology. 221:291
- de Paus RA, et al. 2013. Mol Immunol. 56:380
- Airoldi I, et al. 2008. Blood. 112:750
- Gene ID
- 3595 View all products for this Gene ID
- UniProt
- View information about IL12RB2 on UniProt.org
Related Pages & Pathways
Pages
Related FAQs
- What is the F/P ratio range of our BV421™ format antibody reagents?
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It is lot-specific. On average it ranges between 2-4.
Other Formats
View All IL12RB2 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-human IL12RB2 | S16020B | FC |
TotalSeq™-D1172 anti-human IL12RB2 | S16020B | PG |
PE anti-human IL12RB2 | S16020B | FC |
Alexa Fluor® 647 anti-human IL12RB2 Antibody | S16020B | FC |
APC anti-human IL12RB2 | S16020B | FC |
Brilliant Violet 421™ anti-human IL12RB2 | S16020B | FC |
TotalSeq™-A1172 anti-human IL12RB2 | S16020B | PG |
TotalSeq™-C1172 anti-human IL12RB2 | S16020B | PG |
TotalSeq™-B1172 anti-human IL12RB2 | S16020B | PG |
Customers Also Purchased
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human IL12RB2
Human peripheral blood lymphocytes were activated for 3 days... -
TotalSeq™-D1172 anti-human IL12RB2
-
PE anti-human IL12RB2
Human peripheral blood lymphocytes were activated for 3 days... -
Alexa Fluor® 647 anti-human IL12RB2 Antibody
Human peripheral blood lymphocytes were activated for 3 days... -
APC anti-human IL12RB2
Human peripheral blood lymphocytes were activated for 3 days... -
Brilliant Violet 421™ anti-human IL12RB2
Human peripheral blood lymphocytes were activated for 3 days... -
TotalSeq™-A1172 anti-human IL12RB2
-
TotalSeq™-C1172 anti-human IL12RB2
-
TotalSeq™-B1172 anti-human IL12RB2
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