Purified anti-human GPR19 Antibody

Pricing & Availability
Clone
K152D10 (See other available formats)
Regulatory Status
RUO
Other Names
G protein-coupled receptor 19 (GPR19), G protein-coupled receptor gpr-nga, GPR-NGA
Isotype
Mouse IgG1, κ
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Product Citations
publications
K152D10_Purified_GPR19_Antibody_FC_021113
Human GPR19 transfected CHO cells were stained with purified GPR19 (clone K152D10) (filled histogram) or purified mouse IgG1, κ isotype control (open histogram), followed by anti-mouse IgG FITC.
  • K152D10_Purified_GPR19_Antibody_FC_021113
    Human GPR19 transfected CHO cells were stained with purified GPR19 (clone K152D10) (filled histogram) or purified mouse IgG1, κ isotype control (open histogram), followed by anti-mouse IgG FITC.
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357001 25 µg $129
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Description

GPR19  is a 415 amino acid protein with two potential glycosylation sites and one disulfide bond that belongs to Orphan G-protein-coupled receptors (GPCRs) with unknown ligand. In mice, GPR19 is highly expressed in the nervous system during embryonic development as well as in specific regions of the mouse adult brain, including the olfactory bulb, the hippocampus, the hypothalamic nuclei, and the cerebellum. It shows low levels of expression in the heart, liver, and kidney. In humans, GPR19 has been reported in regions overlapping with the dopamine D2 receptor in the brain and peripheral nervous system. It was also found in human embryonic stem cells. GPR19 gene was reported to be overexpressed with small cell lung cancer and metastatic melanomas.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
N-terminal Peptide
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2561844 (BioLegend Cat. No. 357001)

Antigen Details

Structure
415 amino acids, seven transmembrane domains, two potential glycosylation site, one disulfide bond
Distribution

Brain and peripheral nervous system

Function
Involved in early development of the nervous system, embryonic stem cells
Biology Area
Immunology
Molecular Family
GPCR
Antigen References

1. Kastner S, et al. 2012. Mol Cancer RES. 10:1343.
2. Riker AI, et al. 2008. BMC Med Genomics. 28:1.
3. O'Dowd BF, et al. 1996. FEBS Lett. 7:325.

Gene ID
2842 View all products for this Gene ID
UniProt
View information about GPR19 on UniProt.org
Go To Top Version: 1    Revision Date: 06/07/2013

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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