PE anti-human CD355 (CRTAM) Antibody

Pricing & Availability
Clone
Cr24.1 (See other available formats)
Regulatory Status
RUO
Other Names
Class I-MHC-Restricted T-cell Associated Molecule
Isotype
Mouse IgG2a, κ
Cr24dot1_PE_011409.jpg
PMA/ionomycin-stimulated (4 hours) human peripheral blood lymphocytes stained with Cr24.1 PE and CD8 (RPA-T8) APC
  • Cr24dot1_PE_011409.jpg
    PMA/ionomycin-stimulated (4 hours) human peripheral blood lymphocytes stained with Cr24.1 PE and CD8 (RPA-T8) APC
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Cat # Size Price Quantity Check Availability
339106 100 tests $317.00
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Description

CRTAM, (class-I MHC-restricted T-cell associated molecule), is homodimer protein belonging to Ig superfamily. It is expressed transiently on activated NK cells,NKT cells and a subset of CD8+ T cells. Nectin-like molecule-2 (Necl2, TSCL1) is the ligand of CRTAM. CRTAM plays an important role in cell adhesion and migration.

Technical data sheet

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
CRTAM-P815 cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Kent S, et al. 2005. Blood. 106:779
Product Citations
  1. Bloom DD, et al. 2018. J Immunother. 41:213. PubMed
RRID
AB_2085907 (BioLegend Cat. No. 339106)

Antigen Details

Structure
Dimer, Ig superfamily
Distribution

Activated NK cells and subset of CD8+ cells

Function
Adhesion and migration
Ligand/Receptor
Nectin-like molecule 2 (Necl2)
Cell Type
NK cells, T cells
Biology Area
Immunology
Molecular Family
Adhesion Molecules, CD Molecules, MHC Antigens
Antigen References

1. Arase N, et al. 2005. Intl. Immunol. 17:1227
2. Kennedy J, et al. 2000. J. Leukoc. Biol. 67:725

Gene ID
56253 View all products for this Gene ID
UniProt
View information about CD355 on UniProt.org
Go To Top Version: 1    Revision Date: 11/30/2012

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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