Loading...

APC anti-mouse CD11c Antibody

Pricing & Availability
Clone
N418 (See other available formats)
Regulatory Status
RUO
Other Names
αX integrin, integrin αX chain, CR4, p150, ITGAX
Isotype
Armenian Hamster IgG
Ave. Rating
Submit a Review
Product Citations
publications
N418
C57BL/6 mouse splenocytes stained with N418 APC and PK136 PE
  • N418
    C57BL/6 mouse splenocytes stained with N418 APC and PK136 PE
See APC spectral data
Cat # Size Price Quantity Check Availability Save
117309 25 µg $33
Check Availability


Need larger quantities of this item?
Request Bulk Quote
117310 100 µg $116
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

CD11c is a 150 kD glycoprotein also known as αX integrin, CR4, and p150. CD11c forms a αXβ2 heterodimer with β2 integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The αXβ2 integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen, and CD54.

Product Details
Technical data sheet

Product Details

Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Armenian Hamster
Immunogen
Mouse spleen dendritic cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The CD11c antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Application Notes

Additional reported applications (for the relevant formats) include: immunoprecipitation3, immunohistochemical staining of acetone-fixed frozen sections3, immunofluorescence microscopy5, 9 (Alexa Fluor® 488 conjugated N418 was used for IHC in frozen sections10), and spatial biology (IBEX)22,23.

Application References

(PubMed link indicates BioLegend citation)
  1. Granucci F, et al. 1997. J. Immunol. 159:1794.
  2. Stokes RW, et al. 1998. J. Immunol. 160:5514.
  3. Metlay JP, et al. 1990. J. Exp. Med. 171:1753. (IHC, IP)
  4. Ma XT, et al. 2006. Cancer Research 66:1169.
  5. Chin RK, et al. 2006. J. Immunol. 177:290. (IF)
  6. Cervantes-Barragan L, et al. 2007. Blood 109:1131. (FC) PubMed
  7. Turnquist HR, et al. 2007. J. Immunol. 178:7018. (FC) PubMed
  8. Benson MJ, et al. 2007. J. Exp. Med. doi:10.1084/jem.20070719. (FC) PubMed
  9. You Y, et al. 2009. J. Immunol. 182:7343. (IF) PubMed
  10. Roland CL, et al. 2009. Mol. Cancer Res. 8:1761. (IHC, FC) PubMed
  11. Wikstrom M, et al.2006. J. Immunol. 177:913. PubMed
  12. Pericolini E, et al. 2008. J. Leukocyte Biol. 83:1286. PubMed
  13. Randall LM, et al. 2008. Infect. Immun.76:3312. PubMed
  14. Fahlen-Yrild L, et al. 2009. J. Immunol. 183:5032. PubMed
  15. Osterholzer JJ, et al. 2009. J. Immunol. 183:8044. PubMed
  16. Bankoti J, et al. 2010. Toxicol. Sci. 115:422. (FC) PubMed
  17. Eisenach PA, et al. 2010. J Cell Sci. 123:4182. PubMed
  18. Leppin K, et al. 2014. Invest. Ophthalmol. Vis. Sci. 55:3603. PubMed
  19. Sakai F, et al. 2014. PLoS One. 9:105370. PubMed
  20. Gibbins JD, et al. 2014. Blood. 124:2953. PubMed
  21. White CE, et al. 2015. J Immunol. 194:697. PubMed
  22. Lu X, et al. 2015. J Immunol. 194:2011. PubMed
  23. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  24. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Ye Y, et al. 2017. Sci Immunol. 2:17. PubMed
  2. Platteel A, et al. 2017. Vaccine.. 10.1016/j.vaccine.2017.10.044. PubMed
  3. Chu LH, et al. 2018. Nat Commun. 9:996. PubMed
  4. Miteva K, et al. 2018. Sci Rep. 8:2820. PubMed
  5. Oyarce C, et al. 2018. Front Immunol. 8:1794. PubMed
  6. Sharma PK, et al. 2018. Cancer Gene Ther. 25:27. PubMed
  7. Nam GH, et al. 2018. Nat Commun. 9:2165. PubMed
  8. Emgård J, et al. 2018. Immunity. 143:419. PubMed
  9. Yuzhu Hou et al. 2018. Immunity. 49(3):490-503 . PubMed
  10. Best SA, et al. 2018. Cell Metab. 27:935. PubMed
  11. Xia P et al. 2018. Immunity. 48(4):688-701 . PubMed
  12. Iwamoto H et al. 2018. Cell metabolism. 28(1):104-117 . PubMed
  13. Mrdjen D et al. 2018. Immunity. 48(2):380-395 . PubMed
  14. Fujita Y et al. 2018. Cell reports. 24(12):3296-3311 . PubMed
  15. Kooreman NG et al. 2018. Cell stem cell. 22(4):501-513 . PubMed
  16. Postat J et al. 2018. Immunity. 49(4):654-665 . PubMed
  17. Alissafi T, et al. 2018. J Clin Invest. 128:3840. PubMed
  18. Cao W, et al. 2017. Immunity. 47:1182. PubMed
  19. Dyer DP et al. 2019. Immunity. 50(2):378-389 . PubMed
  20. Zhao J, et al. 2019. Nat Commun. 10:899. PubMed
  21. Angelidis I, et al. 2019. Nat Commun. 10:963. PubMed
  22. Yáñez A et al. 2017. Immunity. 47(5):890-902 . PubMed
  23. Sadtler K, et al. 2017. Tissue Eng Part A. 23:1044. PubMed
  24. Zeng J, et al. 2018. J Immunol. 200:3407. PubMed
  25. Niknam S, et al. 2018. Clin Cancer Res. 24:5735. PubMed
  26. Trinh HKT, et al. 2019. J Cell Mol Med. 23:3441. PubMed
  27. Agelidis A, et al. 2019. Front Immunol. 10:500. PubMed
  28. Matsumura T et al. 2019. Cell Rep. 27(2):561-571 . PubMed
  29. Ramakrishna C, et al. 2019. Nat Commun. 10:2153. PubMed
  30. Hu J, et al. 2019. Mol Ther Nucleic Acids. 16:650. PubMed
  31. Kubli SP, et al. 2019. Nat Commun. 10:2678. PubMed
  32. Li C, et al. 2018. Cell. 174:285. PubMed
  33. Page N, et al. 2018. Immunity. 48:937. PubMed
  34. Budida R, et al. 2017. Eur J Immunol. 47:1819. PubMed
  35. He J, et al. 2019. J Clin Invest. 130. PubMed
  36. Wang C, et al. 2018. Sci Transl Med. 10. PubMed
  37. Lin SY, et al. 2017. Autophagy. 14:778. PubMed
  38. Yamada S, et al. 2018. Arterioscler Thromb Vasc Biol. 38:994. PubMed
  39. Kim TJ, et al. 2019. Nat Commun. 10:3258. PubMed
  40. Kemp V, et al. 2018. Cancer Gene Ther. 26:268. PubMed
  41. Takeda Y, et al. 2018. Innate Immun. 24:323. PubMed
  42. Shi L, et al. 2019. Theranostics. 9:4115. PubMed
  43. Garo LP, et al. 2019. Cell Rep. 28:3353. PubMed
  44. Yadava K et al. 2019. Elife. 8 pii: e44821. PubMed
  45. Nagashima H et al. 2019. Immunity. 51(4):682-695 . PubMed
  46. Liu D et al. 2019. Immunity. 51(1):64-76 . PubMed
  47. Dmitrieva‐Posocco O et al. 2019. Immunity. 50(1):166-180 . PubMed
  48. Sparber F, et al. 2019. Cell Host Microbe. 25:389. PubMed
  49. Shin M et al. 2019. Cell Chem Biol. 26(7):1036-1041 . PubMed
  50. Zhang LJ, et al. 2019. Immunity. 50:121. PubMed
  51. Lechner AJ et al. 2017. Cell stem cell. 21(1):120-134 . PubMed
  52. Varol D et al. 2017. Immunity. 46(6):1030-1044 . PubMed
  53. Alexander Mildner et al. 2017. Immunity. 46(5):849-862 . PubMed
  54. Morrissey MA, et al. 2018. Elife. 7:e36688. PubMed
  55. Gu H, et al. 2018. Aging (Albany NY). 1.525694444. PubMed
  56. Kramer K, et al. 2017. ACS Omega. 0.240972222. PubMed
  57. Matisz CE, et al. 2018. Am J Pathol. 188:2589. PubMed
  58. Liu W, et al. 2019. Epigenetics. 1.192361111. PubMed
  59. Burgener SS, et al. 2019. Cell Rep. 27:3646. PubMed
  60. Yahagi A, et al. 2019. RMD Open. 5:e000853. PubMed
  61. Tomida S, et al. 2019. Sci Rep. 9:10751. PubMed
  62. Hong Y, et al. 2019. J Extracell Vesicles. 8:1670893. PubMed
  63. Wang S, et al. 2020. J Cell Mol Med. 24:722. PubMed
  64. Dokoshi T, et al. 2020. Cell Rep. 30:61. PubMed
  65. Tsuchiya N, et al. 2020. Cell Reports. 29(1):162-175.e9.. PubMed
  66. Li Y, et al. 2020. Cell Rep. 30:1753. PubMed
  67. Kunishita Y, et al. 2020. Front Immunol. 11:98. PubMed
  68. Brenner E, et al. 2020. Nat Commun. 11:1335. PubMed
  69. Huang WC, et al. 2020. NPJ Vaccines. 5:23. PubMed
  70. Van Den Eeckhout B, et al. 2020. NPJ Vaccines. 0.252777778. PubMed
  71. Lai NY, et al. 2020. Cell. 180:33:00. PubMed
  72. Kawabe T, et al. 2020. Nat Commun. 2.795833333. PubMed
  73. Lisk C, et al. 2020. Front Immunol. 1.329166667. PubMed
  74. Cheng Y, et al. 2020. PLoS Pathog. 16:e1008569. PubMed
  75. McCauley ME, et al. 2020. Nature. 585(7823):96-101. PubMed
  76. Bode K, et al. 2020. Cell Reports. 29(13):4435-4446.e9.. PubMed
  77. Liu Z, et al. 2020. Cell. 178(6):1509-1525.e19.. PubMed
  78. Chitu V, et al. 2020. Cell Reports. 30(9):3004-3019. PubMed
  79. Blumenthal D, et al. 2020. eLife. 9:e55995.. PubMed
  80. Kunimura K, et al. 2020. Cell Reports. 29(9):2823-2834.e7.. PubMed
  81. Xu H, et al. 2020. Immunity. 51(4):696-708.e9.. PubMed
  82. He Y, et al. 2020. Sci Adv. 6:eaba7589. PubMed
  83. Bertino P, et al. 2019. Oncoimmunology. 8:1601482. PubMed
  84. Kalafati L, et al. 2020. Cell. 183:771. PubMed
  85. Marsh L, et al. 2009. Am J Physiol Lung Cell Mol Physiol. 296:L442. PubMed
  86. Gentschev I, et al. 2012. PLoS One. 7:e37239. PubMed
  87. Berthold N, et al. 2013. Antimicrob Agents Chemother. 57:402. PubMed
  88. Riva A, et al. 2013. J Immunol. 190:5961. PubMed
  89. Bak S, et al. 2008. Mol Immunol. 45:1414. PubMed
  90. Glauser D, et al. 2013. J Virol. 87:10828. PubMed
  91. Takaki H, et al. 2013. J Immunol. 191:4740. PubMed
  92. Zhao W, et al. 2014. Clin Vaccine Immunol. 21:74. PubMed
  93. Prado C, et al. 2012. J Immunol. 188:3062. PubMed
  94. Ustarroz-Cano M, et al. 2012. J Immunotoxicol. 9:374. PubMed
  95. Bunn P, et al. 2014. J Immunol. 192:3709. PubMed
  96. Madan-Lala R, et al. 2014. J Immunol. 192:4263. PubMed
  97. Xia S, et al. 2014. J Leukoc Biol. 95:733. PubMed
  98. Markey K, et al. 2014. J Immunol. 192:5426. PubMed
  99. Narusawa M, et al. 2014. Cancer Immunol Res. 2:568. PubMed
  100. Aebischer D, et al. 2014. PLoS One. 9:99297. PubMed
  101. Sakai F, et al. 2014. PLoS One. 9:105370. PubMed
  102. Gibbins J, et al. 2014. Blood. 124:2953. PubMed
  103. White C, et al. 2015. J Immunol. 194:697. PubMed
  104. Lu X, et al. 2015. J Immunol. 194:2011. PubMed
  105. Koyama M, et al. 2015. J Exp Med. 212: 1303 - 1321. PubMed
  106. Qian F, et al. 2015. J Mol Cell Biol. . PubMed
  107. Gereke M, et al. 2012. J Vis Exp. 70: 4322. PubMed
  108. Wegmann F, et al. 2015. Clin Vaccine Immunol. 22: 1004-1012. PubMed
  109. Tozuka M, et al. 2016. J Dermatol Sci. 82: 38-45. PubMed
  110. Spinner C, et al. 2015. Sci Rep. 5:16269. PubMed
  111. Mainini F, et al. 2015. PLoS One. 10: 0145403. PubMed
  112. Montes de Oca M, et al. 2016. PLoS Pathog. 12: 1005398. PubMed
  113. Singhal P, et al. 2016. Proc Natl Acad Sci U S A. 113: 122 - 127. PubMed
  114. Pelly V, et al. 2016. Mucosal Immunol. 10.1038/mi.2016.4. PubMed
  115. Nocera D, et al. 2016. J Immunol. 196: 2860 - 2869. PubMed
  116. Peng X, et al. 2016. J Cell Sci. 129: 1831 - 1842. PubMed
  117. Upadhya R, et al. 2016. MBio. 7: 00547-16. PubMed
  118. Sellau J, et al. 2016. Sci Rep. 6:28058. PubMed
  119. Coppo M, et al. 2016. Nat Commun. 7:12254. PubMed
  120. Gujar R, et al. 2016. J Immunol. 197: 1650 - 1662. PubMed
  121. Hrdinka M, et al. 2016. PLoS One. 11: 0162863. PubMed
  122. Martins R, et al. 2016. Nat Immunol. 17:1361-1372. PubMed
  123. Sebina I, et al. 2016. PLoS Pathog. 12:e1005999. PubMed
  124. Liu M, et al. 2016. PLoS One. 11:e0166165. PubMed
  125. Lee L, et al. 2016. PLoS One. 11:e0167693. PubMed
  126. O'Shea NR, Chew TS 2016. J Crohns Colitis. 10(12):1417-1427. PubMed
  127. Aguilera T, et al. 2016. Nat Commun. 7:13898. PubMed
  128. Cerina M, et al. 2017. Brain Behav Immun. 59:103-117. PubMed
  129. Kramer K, et al. 2017. Mol Ther. 25(1):62-70. PubMed
  130. Yin X, et al. 2020. Cell Rep. 33:108278. PubMed
  131. Huang WC, et al. 2020. Adv Mater. 32:e2005637. PubMed
  132. Wanner-Seleznik GM, et al. 2020. Immunohorizons. 0.644444444. PubMed
  133. Cortez MA, et al. 2020. Nat Commun. 3.819444444. PubMed
  134. Wang H, et al. 2020. Nat Mater. 1.655555556. PubMed
  135. Miller CM, et al. 2020. J Virol. 94:00:00. PubMed
  136. Dobson HE, et al. 2020. Mucosal Immunol. 0.901388889. PubMed
  137. Aguilera TA, et al. 2020. Clin Cancer Res. 26:2972. PubMed
  138. Wang Y, et al. 2021. Sci Rep. 1.429861111. PubMed
  139. Wang Y, et al. 2021. Nat Commun. 0.570833333. PubMed
  140. Li N, et al. 2021. eLife. 10:00. PubMed
  141. Marjanovic ND, et al. 2020. Cancer Cell. 38(2):229-246.e13. PubMed
  142. Liu Z, et al. 2021. Immunity. 54(2):247-258.e7. PubMed
  143. Han C, et al. 2021. Cell Reports. 34(6):108706. PubMed
  144. Deerhake ME, et al. 2021. Immunity. 54(3):484-498.e8. PubMed
  145. Zeng W, et al. 2021. STAR Protocols. 2(1):100361. PubMed
  146. He Y, et al. 2021. Cell Metabolism. 33(5):988-1000.e7. PubMed
  147. de Mingo Pulido , et al. 2021. Immunity. 54(6):1154-1167.e7. PubMed
  148. Ryu S, et al. 2021. eLife. 0.416666666666667. PubMed
  149. Li C, et al. 2021. Cell Metabolism. 33(8):1610-1623.e5. PubMed
  150. Gozgit JM, et al. 2021. Cancer Cell. :. PubMed
  151. Zhao L, et al. 2021. STAR Protocols. 2:100732. PubMed
  152. Mulas F, et al. 2020. Cell Mol Immunol. . PubMed
  153. Lin C, et al. 2020. Cancer Immunol Res. 632:8. PubMed
  154. Yu AI, et al. 2020. Cell Rep. 107471:31. PubMed
  155. Shan B, et al. 2020. Nat Metab. 1332:2. PubMed
  156. Covarrubias AJ, et al. 2020. Nat Metab. 1265:2. PubMed
  157. Onai N, et al. 2020. Int J Mol Sci. :22. PubMed
  158. Nam J, et al. 2021. Adv Sci (Weinh). 2002577:8. PubMed
  159. Dos Santos Dias L, et al. 2021. PLoS Pathog. e1009324:17. PubMed
  160. Li X, et al. 2021. Cell Death Dis. 12:314. PubMed
  161. Rana MN, et al. 2021. Front Pharmacol. 12:643215. PubMed
  162. Carlson PM, et al. 2021. J Immunol. 207:720. PubMed
  163. Pandey S, et al. 2020. Cell Syst. 11:495. PubMed
  164. Yuan B, et al. 2021. J Immunother Cancer. 9:. PubMed
  165. Jiang Y, et al. 2021. Nat Commun. 12:742. PubMed
  166. Van Den Eeckhout B, et al. 2020. NPJ Vaccines. 5:64. PubMed
  167. Huang WC, et al. 2020. NPJ Vaccines. 5:23. PubMed
  168. Shi GN, et al. 2021. Ther Adv Med Oncol. 13:1758835920987056. PubMed
  169. Lisk C, et al. 2021. Front Immunol. 12:624197. PubMed
  170. Garo LP, et al. 2021. Nat Commun. 12:2419. PubMed
  171. Zhang XW, et al. 2021. Oncoimmunology. 10:1920739. PubMed
  172. Kulkarni NN, et al. 2021. J Biol Chem. 297:100828. PubMed
  173. Shah D, et al. 2021. Oncoimmunology. 10:1939601. PubMed
  174. Tang Z, et al. 2021. Stem Cell Res Ther. 12:397. PubMed
  175. Fischer FA, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  176. Chao JL, et al. 2021. Cell Rep Med. 2:100399. PubMed
  177. Maulloo CD, et al. 2021. Front Immunol. 12:714842. PubMed
  178. Nicholls J, et al. 2021. Front Cell Dev Biol. 9:737880. PubMed
  179. Dokoshi T, et al. 2021. J Clin Invest. 131:. PubMed
  180. Zhang B, et al. 2021. Nature. 599:471. PubMed
  181. Stump CT, et al. 2021. Open Biol. 11:210245. PubMed
  182. Wiede F, et al. 2021. Cancer Discov. Online ahead of print. PubMed
  183. Akhtar MN, et al. 2020. PLoS Pathog. 16:e1009136. PubMed
  184. Boulch M, et al. 2021. Sci Immunol. 6:. PubMed
  185. Wang X, et al. 2021. Sci Transl Med. 13:. PubMed
  186. Zhong J, et al. 2021. Commun Biol. 4:865. PubMed
  187. Meng W, et al. 2021. JCI Insight. 6:. PubMed
  188. Klarquist J, et al. 2021. Cell Rep. 36:109591. PubMed
  189. Zhou J, et al. 2021. Int J Med Sci. 18:3516. PubMed
  190. Suryawanshi RK, et al. 2021. Nat Commun. 12:6020. PubMed
  191. Aggarwal N, et al. 2021. Cell Rep. 37:110170. PubMed
  192. Jiang Q, et al. 2022. Theranostics. 12:59. PubMed
  193. Du Y, et al. 2022. Nat Commun. 13:231. PubMed
  194. Sauter M, et al. 2022. iScience. 25:103677. PubMed
  195. Xiao Y, et al. 2022. Nat Commun. 13:758. PubMed
  196. Ye P, et al. 2022. Front Cardiovasc Med. 8:810477. PubMed
  197. Vogel A, et al. 2022. Cell Rep. 38:110420. PubMed
  198. Xu M, et al. 2022. Genes Dis. 9:429. PubMed
  199. Rosina M, et al. 2022. Cell Metab. 34:533. PubMed
  200. Hao F, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  201. Lang V, et al. 2021. Elife. 10:. PubMed
  202. Xiao Z, et al. 2022. Mater Today Bio. 15:100297. PubMed
  203. Spiljar M, et al. 2021. Cell Metab. 33:2231. PubMed
  204. Jing L, et al. 2022. Front Immunol. 13:864995. PubMed
  205. Lefebvre MN, et al. 2021. Cell Rep. 37:109956. PubMed
  206. Chen WS, et al. 2021. Cell Rep. 37:109974. PubMed
  207. Almeida AS, et al. 2021. Bio Protoc. 11:e4012. PubMed
  208. Almeida AS, et al. 2021. Bio Protoc. 11:e4012. PubMed
  209. Li H, et al. 2022. iScience. 25:104481. PubMed
  210. Harding CL, et al. 2020. Front Cell Infect Microbiol. 10:328. PubMed
  211. Tukaramrao DB, et al. 2021. Cancers (Basel). 13:. PubMed
  212. McAlpine CS, et al. 2021. Nature. 595:701. PubMed
  213. Smith LK, et al. 2021. Elife. 10:. PubMed
  214. Wüthrich M, et al. 2021. MBio. 12:e0201821. PubMed
  215. Yang Y, et al. 2021. Sci Adv. 7:eabf6290. PubMed
  216. Formaglio P, et al. 2021. Immunity. 54:2724. PubMed
  217. Kim S, et al. 2021. Elife. 10:. PubMed
  218. Takahashi N, et al. 2022. Tohoku J Exp Med. 257:171. PubMed
  219. Zhang C, et al. 2022. Nat Commun. 13:3468. PubMed
  220. Huang T, et al. 2022. Nat Commun. 13:3489. PubMed
  221. Zhou X, et al. 2022. Front Pharmacol. 13:887263. PubMed
  222. Zhou HF, et al. 2022. Front Pharmacol. 13:778755. PubMed
  223. Wiernicki B, et al. 2022. Nat Commun. 13:3676. PubMed
  224. Wang B, et al. 2022. Nat Commun. 13:3821. PubMed
  225. Schneider KM, et al. 2022. Nat Commun. 13:3964. PubMed
  226. Cho YK, et al. 2022. Nat Commun. 13:4084. PubMed
  227. Zhu Y, et al. 2022. Nat Commun. 13:4282. PubMed
  228. Helm M, et al. 2022. Life (Basel). 12:. PubMed
  229. Grube J, et al. 2022. Cell Death Dis. 13:704. PubMed
  230. Shen H, et al. 2022. Nat Commun. 13:5013. PubMed
  231. Li Q, et al. 2022. Cell Rep. 40:111308. PubMed
  232. Xiong A, et al. 2022. EBioMedicine. 83:104239. PubMed
  233. Woodring T, et al. 2022. iScience. 25:104934. PubMed
  234. Yang J, et al. 2022. Microbiome. 10:149. PubMed
  235. Dye BR, et al. 2020. Biomaterials. 234:119757. PubMed
  236. Sethuraman SN, et al. 2020. Theranostics. 10:3397. PubMed
  237. Minute L, et al. 2020. J Immunother Cancer. 8:. PubMed
  238. Zou J, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:983. PubMed
  239. Liu Q, et al. 2021. Adv Mater. 33:e2102852. PubMed
  240. Li W, et al. 2021. Front Pharmacol. 12:697483. PubMed
  241. Gawish R, et al. 2022. Elife. 11:. PubMed
  242. Kohn EM, et al. 2022. J Immunol. 208:1417. PubMed
  243. Wang Y, et al. 2022. Front Immunol. 13:767630. PubMed
  244. Bezu L, et al. 2022. J Immunother Cancer. 10:. PubMed
  245. Qian Z, et al. 2022. Biomedicines. 10:. PubMed
  246. Wang Y, et al. 2022. J Control Release. 349:118. PubMed
  247. Michalaki C, et al. 2022. Curr Protoc. 2:e505. PubMed
  248. Liang W, et al. 2022. Methods Mol Biol. 2574:221. PubMed
  249. Sobecki M, et al. 2022. Cell Stem Cell. 29:1459. PubMed
  250. Tan L, et al. 2022. Biochem Biophys Rep. 32:101351. PubMed
  251. Yu L, et al. 2022. Front Immunol. 13:937331. PubMed
  252. Kitai H, et al. 2022. BMC Biol. 20:248. PubMed
  253. Xue G, et al. 2021. Cancer Cell. 39:1610. PubMed
  254. Li H, et al. 2022. Cancer Cell. 40:36. PubMed
  255. Xin B, et al. 2022. Hepatology. 76:630. PubMed
  256. Huis In 't Veld LGM, et al. 2022. Cell Mol Life Sci. 79:231. PubMed
  257. Chae CS, et al. 2022. Cancer Discov. 12:1904. PubMed
  258. Minichino D, et al. 2022. J Leukoc Biol. 112:1089. PubMed
  259. Blanco LP, et al. 2022. Arthritis Rheumatol. 74:1971. PubMed
  260. Que W, et al. 2022. Sci Adv. 8:eabo4413. PubMed
  261. Liu Z, et al. 2022. Cancer Commun (Lond). 42:971. PubMed
  262. Chen C, et al. 2022. Sci Adv. 8:eabo4363. PubMed
  263. Guasconi L, et al. 2022. J Fungi (Basel). 8: . PubMed
  264. McAlpine CS, et al. 2022. J Exp Med. 219: . PubMed
  265. Zhu J, et al. 2022. Research (Wash D C). 2022:9816272. PubMed
  266. Klaus T, et al. 2022. JCI Insight. 7: . PubMed
  267. Chen Y, et al. 2023. Adv Healthc Mater. 12:e2202085. PubMed
  268. Kraemer AN, et al. 2022. Front Immunol. 13:933191. PubMed
  269. Fan R, et al. 2023. J Immunother Cancer. 11: . PubMed
  270. Taniguchi S, et al. 2023. Nat Commun. 14:143. PubMed
  271. Wang D, et al. 2023. J Exp Clin Cancer Res. 42:26. PubMed
  272. Zhao X, et al. 2022. Cell Mol Immunol. 19:540. PubMed
  273. Duan H, et al. 2022. Adv Sci (Weinh). 9:e2103719. PubMed
  274. Akhtar MN, et al. 2022. MBio. 13:e0330921. PubMed
  275. Sauter M, et al. 2022. STAR Protoc. 3:101664. PubMed
  276. Sia ZR, et al. 2022. J Virol. 96:e0100622. PubMed
  277. Chen Y, et al. 2022. Am J Cancer Res. 12:5286. PubMed
  278. Tan J, et al. 2023. Acta Pharm Sin B. 13:632. PubMed
  279. Shi X, et al. 2023. iScience. 26:106143. PubMed
  280. Pasqual G, et al. 2023. Methods Mol Biol. 2618:71. PubMed
  281. Zhang X, et al. 2023. Front Immunol. 14:1116749. PubMed
  282. Seclì L, et al. 2023. J Immunother Cancer. 11:. PubMed
  283. Li Y, et al. 2023. Front Cell Infect Microbiol. 13:1117230. PubMed
  284. Bhaskar A, et al. 2023. iScience. 26:106644. PubMed
  285. Wang D, et al. 2023. Nat Commun. 14:2943. PubMed
  286. Song J, et al. 2023. iScience. 26:106753. PubMed
  287. Song S, et al. 2023. Bioact Mater. 28:358. PubMed
RRID
AB_313778 (BioLegend Cat. No. 117309)
AB_313779 (BioLegend Cat. No. 117310)

Antigen Details

Structure
Integrin α-chain, associates with integrin β2 (CD18), 150 kD
Distribution

Dendritic cells, NK cells, intestinal intraepithelial lymphocytes (IEL), some activated T cells

Function
Cellular adhesion
Ligand/Receptor
iC3b, fibrinogen
Cell Type
Dendritic cells, Epithelial cells, NK cells, T cells, Tregs
Biology Area
Cell Adhesion, Cell Biology, Costimulatory Molecules, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen Facts Book Academic Press.
2. Springer TA. 1994. Cell 76:301.
3. Lopez-Rodriguez C, et al. 1996. J. Immunol. 156:3780.

Gene ID
16411 View all products for this Gene ID
UniProt
View information about CD11c on UniProt.org
Go To Top Version: 1    Revision Date: 11/30/2012

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

ProductsHere
Login/Register
Remember me
Forgot your password? Reset Password
Request an Account