Loading...

APC/Cyanine7 anti-mouse/human CD11b Antibody

Pricing & Availability
Clone
M1/70 (See other available formats)
Regulatory Status
RUO
Other Names
αM integrin, Mac-1, Mo1, CR3, Ly-40, C3biR, ITGAM
Isotype
Rat IgG2b, κ
Ave. Rating
Submit a Review
Product Citations
publications
M1slash70_APCCy7_021808
C57BL/6 mouse bone marrow stained with M1/70 APC/Cyanine7
  • M1slash70_APCCy7_021808
    C57BL/6 mouse bone marrow stained with M1/70 APC/Cyanine7
See APC/Cyanine7 spectral data
Cat # Size Price Quantity Check Availability Save
101225 25 µg $94
Check Availability


Need larger quantities of this item?
Request Bulk Quote
101226 100 µg $216
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

Product Details
Technical data sheet

Product Details

Reactivity
Mouse,Human,Cynomolgus,Rhesus
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
C57BL/10 splenocytes
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with APC/Cyanine7 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Application Notes

Clone M1/70 has been verified for immunocytochemistry (ICC) and frozen immunohistochemistry (IHC-F).

Additional reported applications (for relevant formats of this clone) include: immunoprecipitation1,4, in vitro blocking3,9,12, depletion2,8, immunofluorescence microscopy6,7,10, immunohistochemistry of acetone-fixed frozen sections5,11-13, and spatial biology (IBEX)35,36. For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) (Cat. No. 101248).

Additional Product Notes
BioLegend is in the process of converting the name APC/Cy7 to APC/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our APC/Cyanine7 products. Please contact Technical Service if you have any questions.
Application References

(PubMed link indicates BioLegend citation)
  1. Springer T, et al. 1978. Eur. J. Immunol. 8:539. (IP)
  2. Ault K and Springer T. 1981. J. Immunol. 126:359. (Deplete)
  3. Springer TA, et al. 1982. Immunol. Rev. 68:171. (Block)
  4. Ho MK and Springer TA. 1983. J. Biol. Chem. 258:2766. (IP)
  5. Flotte TJ, et al. 1983. Am. J. Pathol. 111:112. (IHC)
  6. Noel GJ, et al. 1990. J. Clin. Invest. 85:208. (IF)
  7. Allen LA and Aderem A. 1996. J. Exp. Med. 184:627 (IF)
  8. D'Amico A and Wu L. 2003. J. Exp. Med. 198:293. (Deplete)
  9. Brickson SJ, et al. 2003. Appl Physiol. 95:969. (Block)
  10. Clatworthy MR and Smith KG. 2004. J. Exp. Med. 199:717. (IF)
  11. Hata H, et al. 2004. J. Clin. Invest. 114:582. (IHC)
  12. Zhang Y, et al. 2002. J. Immunol. 168:3088. (IHC)
  13. Iwasaki A and Kelsall BL. 2001. J. Immunol. 166:4884 (IHC, FC)
  14. Tailleux L. 2003. J. Exp. Med. 197:121. (Block, FC)
  15. Olver S, et al. 2006. Cancer Research 66:571. (FC)
  16. Tan SL, et al. 2006. J. Immunol. 176:2872. (FC) PubMed
  17. Ponomarev ED, et al. 2006. J. Immunol. 176:1402. (FC)
  18. Dzhagalov I, et al. 2007. Blood 109:1620. (FC)
  19. Fazilleau N, et al. 2007. Nature Immunol. 8:753.
  20. Rasmussen JW, et al. 2006. Infect. Immun.74:6590. PubMed
  21. Napimoga MH, et al. 2008. J. Immunol. 180:609. PubMed
  22. Elqaraz-Carmon V, et al. 2008. J. Lipid. Res. 49:1894. PubMed
  23. Kim DD, et al. 2008. Blood 112:1109. PubMed
  24. Guo Y, et al. 2008. Blood 112:480. PubMed
  25. Norian LA, et al. 2009. Cancer Res. 69:3086. (FC) PubMed
  26. Baumgartner CK, et al. 2010. J. Immunol. 184:573. PubMed
  27. Charles N, et al. 2010. Nat. Med. 16:701. (FC) PubMed
  28. Whiteland J, et al. 1995. J. Histochem. Cytochem. 43:313. (IHC)
  29. Weber GF, et al. 2014. J Exp Med. 211:1243. PubMed
  30. Ashok A, et al. 2015. Toxicol Sci. 143:64. PubMed
  31. Price PJ, et al. 2015. J Immunol. 194:1164. PubMed
  32. Doni A, et al. 2015. J Exp Med. 212:905. PubMed
  33. Ferreira R, et al. 2016. J Infect Dis. 213: 669 - 673. PubMed
  34. Peterson VM, et al. 2017. Nat. Biotechnol. 35:936. (PG)
  35. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  36. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Sweet R, et al. 2017. J Immunol. 10.4049/jimmunol.1600861. PubMed
  2. Sia J, et al. 2017. PLoS Pathog.. 10.1371/journal.ppat.1006530. PubMed
  3. Clarke F,et al. 2017. PLoS One. 10.1371/journal.pone.0186625. PubMed
  4. Zhao J, et al. 2018. Stem Cell Reports. 10:180. PubMed
  5. Duarte D, et al. 2018. Cell Stem Cell. 22:64. PubMed
  6. Liu S, et al. 2018. Front Immunol. 29:208. PubMed
  7. Yuzhu Hou et al. 2018. Immunity. 49(3):490-503 . PubMed
  8. Kunimoto H, et al. 2018. Cancer Cell. 33:44. PubMed
  9. Kleppe M et al. 2018. Cancer cell. 33(1):29-43 . PubMed
  10. Landon J Edgar et al. 2018. Cell chemical biology. 26(1):131-136 . PubMed
  11. Giambra V et al. 2018. Cell stem cell. 23(5):714-726 . PubMed
  12. Cong J et al. 2018. Cell metabolism. 28(2):243-255 . PubMed
  13. Celik H, et al. 2018. Cancer Cell. 34:741. PubMed
  14. Lino AC et al. 2018. Immunity. 49(1):120-133 . PubMed
  15. Syed I et al. 2018. Cell metabolism. 27(2):419-427 . PubMed
  16. Filipello F et al. 2018. Immunity. 48(5):979-991 . PubMed
  17. Cho SM et al. 2018. Journal of neurochemistry. 148(5):625-638 . PubMed
  18. Luo H, et al. 2019. Cell Rep. 26:945. PubMed
  19. Martínez‐López M et al. 2019. Immunity. 50(2):446-461 . PubMed
  20. Nagatake T, et al. 2018. Int Immunol. 30:471. PubMed
  21. Chen Z, et al. 2019. J Exp Med. 216:152. PubMed
  22. Crane A, et al. 2018. Alzheimers Dement. 14:243. PubMed
  23. Li CJ, et al. 2018. J Clin Invest. 128:5251. PubMed
  24. Qiao S, et al. 2019. J Neuroinflammation. 16:4. PubMed
  25. Mamedov MR, et al. 2018. Immunity. 48:350. PubMed
  26. Perry JSA, et al. 2018. Immunity. 48:923. PubMed
  27. Niknam S, et al. 2018. Clin Cancer Res. 24:5735. PubMed
  28. Mathur R, et al. 2019. Mucosal Immunol. 12:612. PubMed
  29. Parlet CP, et al. 2019. Cell Rep. 27:187. PubMed
  30. Fachi JL et al. 2019. Cell reports. 27(3):750-761 . PubMed
  31. Goldstein JM et al. 2019. Cell reports. 27(4):1254-1264 . PubMed
  32. Casulli J, et al. 2019. Nat Commun. 10:2121. PubMed
  33. Nagatake T, et al. 2018. J Allergy Clin Immunol. 142:470. PubMed
  34. Wang H, et al. 2019. Immunotherapy. 11:101. PubMed
  35. Mariani SA, et al. 2019. Immunity. 50:1439. PubMed
  36. Li A, et al. 2018. Cancer Lett. 431:54. PubMed
  37. Codina A, et al. 2019. Cell Syst. 8:136. PubMed
  38. Yin S et al. 2019. Cancer cell. 35(2):283-296 . PubMed
  39. Zhou J, et al. 2019. Immunity. 50:403. PubMed
  40. Miragaia RJ, et al. 2019. Immunity. 50:493. PubMed
  41. Xiong X et al. 2019. Mol Cell. 75(3):644-660 . PubMed
  42. McKenzie MD, et al. 2019. Cell Stem Cell. 25:258. PubMed
  43. Säwen P et al. 2018. eLife. 7 pii: e41258. PubMed
  44. Zhang S, et al. 2019. Cell Metab. 29:443. PubMed
  45. Hulsmans M et al. 2017. Cell. 169(3):510-522 . PubMed
  46. Ano Y, et al. 2017. J Biol Chem. 292:3720. PubMed
  47. Mishra BB, et al. 2017. Nat Microbiol. 2:17072. PubMed
  48. Zhang K, et al. 2018. PLoS Pathog. 14:e1006925. PubMed
  49. Li B, et al. 2019. Oncol Rep. 41:608. PubMed
  50. Delás MJ, et al. 2019. Cell Rep. 27:719. PubMed
  51. Zhang H, et al. 2019. Mol Cell. 76:110. PubMed
  52. Kashyap AS, et al. 2019. Cell Rep. 28:3367. PubMed
  53. Larson–Casey JL, et al. 2019. J Clin Invest. 129:4962. PubMed
  54. Davis FM, et al. 2019. Arterioscler Thromb Vasc Biol. 39:2353. PubMed
  55. Nowak W, et al. 2020. EBioMedicine. 50:290-305.. PubMed
  56. Zhao Y, et al. 2020. Immunity. 51(6):1059-1073.e9.. PubMed
  57. Wong E, et al. 2019. Cell Rep. 29:3047. PubMed
  58. Yu X, et al. 2020. Nat Commun. 0.641666667. PubMed
  59. Yoshida H, et al. 2019. Cell. 176:897. PubMed
  60. Davidson S, et al. 2020. Cell Reports. 31(7):107628. PubMed
  61. Yoshimi A, et al. 2019. Nature. 574:273. PubMed
  62. Li Y, et al. 2020. Cell Rep. 30:1753. PubMed
  63. Bhattacherjee A, et al. 2019. Commun Biol. 2:450. PubMed
  64. Cabal-Hierro L, et al. 2020. Nat Commun. 11:1406. PubMed
  65. Yang M, et al. 2020. Cell Prolif. 53:e12784. PubMed
  66. Di Gioia M, et al. 2020. Nat Immunol. 21:42. PubMed
  67. Lee MC, et al. 2017. J Immunol. 198:3565. PubMed
  68. Carestia A, et al. 2019. Cell Rep. 28:896. PubMed
  69. Saika A, et al. 2020. FASEB Bioadv. 2:59. PubMed
  70. García-Bonilla M, et al. 2020. Stem Cell Res Ther. 11:121. PubMed
  71. Soncin I, et al. 2018. Nat Commun. 9:582. PubMed
  72. Pietronigro E, et al. 2019. Sci Rep. 9:12055. PubMed
  73. Kim M, et al. 2018. Immunity. 49:151. PubMed
  74. Choi EW, et al. 2020. Sci Rep. 10:12001. PubMed
  75. Viny AD, et al. 2019. Cell Stem Cell. 25:682. PubMed
  76. Harel M, et al. 2020. Cell. 179(1):236-250.e18.. PubMed
  77. Hoyer FF, et al. 2020. Immunity. 51(5):899-914.e7.. PubMed
  78. Ge Y, et al. 2020. Mucosal Immunol. 13:34. PubMed
  79. Brown A, et al. 2012. Arterioscler Thromb Vasc Biol. 32:2122. PubMed
  80. Glass A, et al. 2013. J Immunol. 190:4830. PubMed
  81. Spees A, et al. 2013. MBio. 2:430. PubMed
  82. Dixit N, et al. 2012. J Immunol. 189:5954. PubMed
  83. Getts D, et al. 2014. Sci Transl Med. 15:219. PubMed
  84. Richardson M, et al. 2014. PLoS Negl Trop Dis. 8:2825. PubMed
  85. Wangdi T, et al. 2014. PLoS Pathog. 10:1004306. PubMed
  86. Zasłona Z, et al. 2014. J Immunol. 193:4245. PubMed
  87. Krueger K, et al. 2014. Stem Cell Reports. 9:1147. PubMed
  88. Ermert D, et al. 2016. PLoS Pathog. 11: 1005043. PubMed
  89. Chung Y, et al. 2014. J Vis Exp. 89: 51660. PubMed
  90. Lammers K, et al. 2015. PLoS One. 10: 0138338. PubMed
  91. Tanaka Y, et al. 2015. PLoS One. 10: 0138621. PubMed
  92. Yabas M, et al. 2016. PLoS One. 11: 0146774. PubMed
  93. Wu X, et al. 2016. Sci Rep. 6:18685. PubMed
  94. Eastman A, et al. 2016. J Immunol . 194: 5999-6010. PubMed
  95. Denk F, et al. 2016. Cell Rep. 15: 1771-1781. PubMed
  96. Aryal B, et al. 2016. Nat Commun. 7:12313. PubMed
  97. Kurkewich J, et al. 2016. PLoS One. 11: 0161468. PubMed
  98. Palamides P, et al. 2016. Dis Model Mech. 9: 985 - 997. PubMed
  99. LM S, et al. 2016. Cell Rep. 16(12): 3286-96. PubMed
  100. Billroth-MacLurg, AC, et al. 2016. J Immunol. 197:2208-2218. PubMed
  101. Diao N, et al. 2016. Sci Rep. 6:34672. PubMed
  102. Kirschbaum K, et al. 2016. Proc Natl Acad Sci U S A. 113: 13227 - 13232. PubMed
  103. Geng S, et al. 2016. Nat Commun. 7:13436. PubMed
  104. Clement M, et al. 2016. PLoS Pathog. 12:e1006050. PubMed
  105. C Khouili S, et al. 2020. Cell Rep. 33:108468. PubMed
  106. Liang W, et al. 2020. Nat Commun. 4.563888889. PubMed
  107. Larson-Casey JL, et al. 2020. PLoS One. 15:e0241323. PubMed
  108. Jeljeli M, et al. 2020. Cell Rep. 33:108325. PubMed
  109. Zhang C, et al. 2020. Cell Rep. 32:108206. PubMed
  110. Cortez MA, et al. 2020. Nat Commun. 3.819444444. PubMed
  111. Savio LEB, et al. 2020. J Cell Sci. 133:00:00. PubMed
  112. Hirata SI, et al. 2020. Allergy. 75:1939. PubMed
  113. Taya M, et al. 2020. Endocr Relat Cancer. 27:261. PubMed
  114. Flores AM, et al. 2020. Nat Nanotechnol. 0.731944444. PubMed
  115. Hagan AS, et al. 2020. Development. 147:00:00. PubMed
  116. Garcia-Fabiani MB, et al. 2020. Methods Enzymol. 632:369. PubMed
  117. Gattas MJ, et al. 2021. International Journal of Molecular Sciences. 22(10):. PubMed
  118. Guldner IH, et al. 2020. Cell. 183(5):1234-1248.e25. PubMed
  119. Rustenhoven J, et al. 2021. Cell. 184(4):1000-1016.e27. PubMed
  120. Murakami K, et al. 2021. Cell Reports. 34(1):108579. PubMed
  121. Daemen S, et al. 2021. Cell Reports. 34(2):108626. PubMed
  122. Kenswil KJG, et al. 2021. Cell Stem Cell. 28(4):653-670.e11. PubMed
  123. Yilmaz B, et al. 2021. Cell Host Microbe. 29(4):650-663.e9. PubMed
  124. Yi W, et al. 2021. Cell Reports. 34(13):108922. PubMed
  125. Delacher M, et al. 2021. Immunity. 54(4):702-720.e17. PubMed
  126. Dallari S, et al. 2021. Cell Host Microbe. 29(6):1014-1029.e8. PubMed
  127. McFarland AP, et al. 2021. Immunity. 54(6):1320-1337.e4. PubMed
  128. Avgustinova A, et al. 2021. Cell Stem Cell. . PubMed
  129. Jenull S, et al. 2021. Cell Reports. 36(3):109406. PubMed
  130. Siolas D, et al. 2021. Cell Reports. 36:109578. PubMed
  131. Luo X, et al. 2021. Neuron. 109:2691. PubMed
  132. Mulas F, et al. 2020. Cell Mol Immunol. . PubMed
  133. Unudurthi SD, et al. 2020. Life Sci. 117440:247. PubMed
  134. Lim CX, et al. 2020. Cell Rep. 3793:30. PubMed
  135. Hutter K, et al. 2020. FEBS J. . PubMed
  136. Wang Z, et al. 2020. J Cell Mol Med. . PubMed
  137. Wei SC, et al. 2020. Cancer Discov. . PubMed
  138. Hu Y, et al. 2021. Bioact Mater. 2905:6. PubMed
  139. Dos Santos Dias L, et al. 2021. PLoS Pathog. e1009324:17. PubMed
  140. Lippeveld M, et al. 2020. Cytometry A. 97:308. PubMed
  141. Witkowski MT, et al. 2020. Cancer Cell. 37:867. PubMed
  142. Das A, et al. 2020. J Bone Miner Res. 36:199. PubMed
  143. Leimkühler NB, et al. 2020. Cell Stem Cell. 28:637. PubMed
  144. Daemen S, et al. 2021. STAR Protoc. 2:100511. PubMed
  145. Pfefferlé M, et al. 2021. Front Immunol. 12:680855. PubMed
  146. San Gil R, et al. 2021. Cells. 10: . PubMed
  147. Zheng C, et al. 2021. J Extracell Vesicles. 10:e12109. PubMed
  148. Chavkin NW, et al. 2021. J Am Heart Assoc. 10:e019904. PubMed
  149. Kleinholz CL, et al. 2021. Sci Rep. 11:15071. PubMed
  150. Panea C, et al. 2021. Commun Biol. 4:913. PubMed
  151. Gordon RA, et al. 2020. PLoS One. 15:e0226396. PubMed
  152. Goggi JL, et al. 2020. Mol Imaging Biol. 22:1392. PubMed
  153. Kornstädt L, et al. 2021. Front Immunol. 11:607048. PubMed
  154. Kobayashi M, et al. 2020. Bio Protoc. 10:e3601. PubMed
  155. Park HJ, et al. 2021. Int J Mol Sci. 22:. PubMed
  156. Inoue D, et al. 2021. Nat Genet. 53:707. PubMed
  157. Go DM, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:715. PubMed
  158. Murdock BJ, et al. 2021. JCI Insight. 6:. PubMed
  159. Savio LEB, et al. 2020. J Cell Sci. 133:jcs237560. PubMed
  160. Larson-Casey JL, et al. 2021. J Biol Chem. :100810. PubMed
  161. Pradhan K, et al. 2021. J Immunol. 206:2980. PubMed
  162. Larson-Casey JL, et al. 2021. FASEB J. 35:e21675. PubMed
  163. Liu X, et al. 2021. Adv Sci (Weinh). 8:e2100233. PubMed
  164. Geng S, et al. 2021. JCI Insight. 6:. PubMed
  165. Shibad V, et al. 2021. Front Immunol. 12:722451. PubMed
  166. Pradhan K, et al. 2021. Front Immunol. 12:778830. PubMed
  167. King R, et al. 2021. Sci Adv. 7:eabj5293. PubMed
  168. Casellas Roman HL, et al. 2020. Leuk Res. 94:106372. PubMed
  169. Mendelsohn AC, et al. 2020. Am J Physiol Cell Physiol. 319:C997. PubMed
  170. Zhang X, et al. 2021. Mol Cancer Res. 19:1076. PubMed
  171. Bhatt D, et al. 2021. J Exp Med. 218:. PubMed
  172. Wang X, et al. 2021. Sci Transl Med. 13:. PubMed
  173. Yokozeki Y, et al. 2021. Biomed Res Int. 2021:7988320. PubMed
  174. Robles-Oteiza C, et al. 2021. Dis Model Mech. 14:. PubMed
  175. Zhang W, et al. 2021. Front Immunol. 12:768435. PubMed
  176. Nagatake T, et al. 2022. Mucosal Immunol. 15:289. PubMed
  177. Naler LB, et al. 2022. Commun Biol. 5:102. PubMed
  178. Karolin A, et al. 2022. Front Pharmacol. 12:789080. PubMed
  179. Zhang X, et al. 2022. Theranostics. 12:1621. PubMed
  180. Schmit T, et al. 2022. Cell Rep. 38:110456. PubMed
  181. Enriquez AB, et al. 2022. iScience. 25:104305. PubMed
  182. Enriquez AB, et al. 2022. iScience. 25:104305. PubMed
  183. Stahlhut M, et al. 2021. Sci Rep. 11:5294. PubMed
  184. Achmus L, et al. 2020. Front Neurol. 11:577971. PubMed
  185. Lau A, et al. 2022. Sci Adv. 8:eabm0142. PubMed
  186. , et al. 2021. Eur J Immunol. 51:2708. PubMed
  187. Gao Z, et al. 2022. J Inflamm Res. 15:3337. PubMed
  188. Wang C, et al. 2021. Cell Rep. 37:110021. PubMed
  189. Nguyen NDNT, et al. 2020. NPJ Vaccines. 5:7. PubMed
  190. Yang F, et al. 2020. Cancer Res. 80:3677. PubMed
  191. Fite BZ, et al. 2021. Sci Rep. 11:927. PubMed
  192. Frost JN, et al. 2021. Med (N Y). 2:164. PubMed
  193. Bhattacherjee A, et al. 2021. Mol Neurodegener. 16:19. PubMed
  194. McAlpine CS, et al. 2021. Nature. 595:701. PubMed
  195. Jing Y, et al. 2021. Front Immunol. 12:651860. PubMed
  196. Wu X, et al. 2021. Elife. 10:. PubMed
  197. Sakamoto T, et al. 2021. Commun Biol. 4:1165. PubMed
  198. Formaglio P, et al. 2021. Immunity. 54:2724. PubMed
  199. Schönberger K, et al. 2022. Cell Stem Cell. 29:131. PubMed
  200. Pan Y, et al. 2022. J Clin Invest. 132:. PubMed
  201. Wang B, et al. 2022. Nat Commun. 13:3821. PubMed
  202. Chen S, et al. 2022. Cancer Discov. :. PubMed
  203. Smith KJ, et al. 2022. PLoS Biol. 20:e3001554. PubMed
  204. Hutter K, et al. 2022. Front Immunol. 13:967914. PubMed
  205. Cheresh P, et al. 2020. Int J Mol Sci. 21:. PubMed
  206. Gómez LA, et al. 2020. Front Microbiol. 11:1586. PubMed
  207. Yang L, et al. 2021. Cell Death Differ. 28:2616. PubMed
  208. Zhang L, et al. 2021. Front Mol Biosci. 8:647647. PubMed
  209. Liu Q, et al. 2021. Adv Mater. 33:e2102852. PubMed
  210. Patterson DG, et al. 2021. J Immunol. 207:1798. PubMed
  211. Anderson-Baucum E, et al. 2021. Cell Metab. 33:1883. PubMed
  212. Golden GJ, et al. 2021. MBio. 12:e0118121. PubMed
  213. Tulyeu J, et al. 2021. Curr Protoc. 1:e283. PubMed
  214. Hoffman D, et al. 2021. Immunity. 54:2712. PubMed
  215. Xu X, et al. 2022. EMBO Rep. 23:e53509. PubMed
  216. Ma S, et al. 2022. Cell Rep. 38:110520. PubMed
  217. Jiang N, et al. 2022. Nat Commun. 13:1511. PubMed
  218. Yang S, et al. 2022. J Exp Med. 219:. PubMed
  219. Vicencio JM, et al. 2022. Cell Death Dis. 13:274. PubMed
  220. Schloss MJ, et al. 2022. Nat Immunol. 23:605. PubMed
  221. Zhang CR, et al. 2022. Blood Cancer Discov. 3:220. PubMed
  222. Lin R, et al. 2022. Cell Death Dis. 13:345. PubMed
  223. Zhu Y, et al. 2022. Clin Transl Med. 12:e887. PubMed
  224. Tomimatsu M, et al. 2022. Sci Rep. 12:16656. PubMed
  225. Yang N, et al. 2022. NPJ Vaccines. 7:120. PubMed
  226. Feng S, et al. 2022. Front Immunol. 13:990522. PubMed
  227. Fu A, et al. 2022. Cell. 185:1356. PubMed
  228. Dolfi B, et al. 2022. Cell Rep. 39:110949. PubMed
  229. Blanco LP, et al. 2022. Arthritis Rheumatol. 74:1971. PubMed
  230. McAlpine CS, et al. 2022. J Exp Med. 219: . PubMed
  231. Balood M, et al. 2022. Nature. 611:405. PubMed
  232. Hill AA, et al. 2023. JCI Insight. 8: . PubMed
  233. Guo J, et al. 2023. Cell Rep Med. 4:100881. PubMed
  234. Fan R, et al. 2023. J Immunother Cancer. 11: . PubMed
  235. Lombard-Vadnais F, et al. 2023. iScience. 26:105852. PubMed
  236. Reticker-Flynn NE, et al. 2022. Cell. 185:1924. PubMed
  237. Murray C, et al. 2022. Int J Mol Sci. 23:. PubMed
  238. Alghamri MS, et al. 2022. ACS Nano. 16:8729. PubMed
  239. Diamantopoulou Z, et al. 2022. Nature. 607:156. PubMed
  240. Chang CY, et al. 2022. Sci Adv. 8:eabq0615. PubMed
  241. Shi H, et al. 2022. Nutrients. 14:. PubMed
  242. Swan SL, et al. 2023. Front Immunol. 14:1085547. PubMed
  243. Le DT, et al. 2023. iScience. 26:106059. PubMed
  244. Gu J, et al. 2023. J Cell Biochem. 124:557. PubMed
  245. Henn RE, et al. 2023. iScience. 26:106164. PubMed
  246. Larson-Casey JL, et al. 2023. JCI Insight. 8:. PubMed
  247. Xiao Y, et al. 2023. EMBO J. 42:e111762. PubMed
  248. Fukuzaki Y, et al. 2023. iScience. 26:106340. PubMed
  249. Wang HY, et al. 2023. Exp Hematol Oncol. 12:35. PubMed
  250. Palakurthi B, et al. 2023. Nat Commun. 14:2109. PubMed
  251. Okano F, et al. 2023. Cancer Res Commun. 3:640. PubMed
  252. Choconta JL, et al. 2023. Immun Ageing. 20:22. PubMed
  253. Ishida K, et al. 2023. Front Immunol. 14:1111729. PubMed
  254. He Y, et al. 2023. Biomolecules. 13:. PubMed
  255. Bhaskar A, et al. 2023. iScience. 26:106644. PubMed
  256. Lan Y, et al. 2023. iScience. 26:106817. PubMed
RRID
AB_830641 (BioLegend Cat. No. 101225)
AB_830642 (BioLegend Cat. No. 101226)

Antigen Details

Structure
Integrin family, associates with integrin β2 (CD18), 170 kD
Distribution

Granulocytes, monocytes/macrophages, dendritic cells, NK cells, subsets of T and B cells

Function
Adhesion, chemotaxis
Ligand/Receptor
ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, fibrinogen
Cell Type
B cells, Dendritic cells, Granulocytes, Macrophages, Monocytes, Neutrophils, NK cells, T cells, Tregs
Biology Area
Cell Adhesion, Cell Biology, Costimulatory Molecules, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Springer TA. 1994. Cell 76:301.
3. Coxon A, et al. 1996. Immunity 5:653.

Gene ID
16409 View all products for this Gene ID 3684 View all products for this Gene ID
UniProt
View information about CD11b on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 11/30/2012

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

ProductsHere
Login/Register
Remember me
Forgot your password? Reset Password
Request an Account