- Clone
- L17F12 (See other available formats)
- Regulatory Status
- RUO
- Workshop
- II T7
- Other Names
- Leu-1, Ly-1, T1, Tp67, Leu1
- Isotype
- Mouse IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
![L17F12_FITC_CD5_Antibody_FC_092315 L17F12_FITC_CD5_Antibody_FC_092315](https://d1spbj2x7qk4bg.cloudfront.net/Admin/Public/GetImage.ashx?Image=/Files/Images/media_assets/products/product_images/L17F12_FITC_CD5_Antibody_FC_092315.jpg&Width=240&Height=300&altFmImage_path=&Compression=90&Crop=5)
-
Human peripheral blood lymphocytes were stained with CD5 (clone L17F12) FITC (filled histogram) or mouse IgG2a, κ FITC isotype control (open histogram).
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
364021 | 25 tests | 58€ | ||||
364022 | 100 tests | 155€ |
CD5, also known as Leu-1, Ly-1 and T1, is a 67 kD single chain type I glycoprotein that is a member of the scavenger receptor superfamily. CD5 is expressed on T cells, thymocytes, B cell subsets, chronic B lymphocytic leukemia (B-CLL), and peripheral blood dendritic cells. CD5 modulates T and B cell receptor signaling, thymocyte maturation, and T-B cell interactions. One of its ligands is CD72.
Product DetailsProduct Details
- Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human T-acute lymphoblastic leukemia (ALL) cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
- Excitation Laser
-
Blue Laser (488 nm)
- Application Notes
-
Additional reported applications (for the relevant formats): immunoprecipitation1,3,4 and immmunohistochemical staining of frozen and formalin-fixed paraffin-embedded sections2,3,5.
- Application References
-
- McAlister MS, et al. 1998. Protein Eng. 11:847. (IP)
- Butmarc JR, et al. 1998. Am. J. Clin. Pathol. 109:682. (IHC)
- Engleman EG, et al. 1981. Proc. Natl. Acad. Sci. USA 78:1791. (IHC, IP)
- Ledbetter JA, et al. 1981. J. Exp. Med. 153:310. (FC, IP)
- Warnke R and Levy R. 1980. J. Histochem. Cytochem. 28:771. (IHC)
- Product Citations
- RRID
-
AB_2566247 (BioLegend Cat. No. 364021)
AB_2566248 (BioLegend Cat. No. 364022)
Antigen Details
- Structure
- Scavenger receptor superfamily, 67 kD
- Distribution
-
Thymocytes, T cells, and subsets of B and dendritic cells.
- Function
- Modulates TCR and BCR signaling, involved in thymocyte maturation and T-B cell interaction
- Ligand/Receptor
- CD72
- Cell Type
- B cells, Dendritic cells, T cells, Thymocytes
- Biology Area
- Costimulatory Molecules, Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Kipps T. 1989. Adv. Immunol. 47:117.
2. Resnick D, et al. 1994. Trends Biochem. Sci. 1:5.
3. Wood GS and Freudenthal PS. 1992. Am. J. Pathol. 141:789. - Gene ID
- 921 View all products for this Gene ID
- UniProt
- View information about CD5 on UniProt.org
Customers Also Purchased
![](/Files/Templates/Designs/BioLegend/images/biomantrans1024.png)
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
Follow Us