- Clone
- CBR LFA-1/2 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Integrin β2 subunit, LFA -1 β subunit, β2 integrin, ITGB2, b2 integrin, beta 2 integrin
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
![CBRspaceLFA-1slash2_Purified_CD18_Antibody_FC_010815 CBRspaceLFA-1slash2_Purified_CD18_Antibody_FC_010815](https://d1spbj2x7qk4bg.cloudfront.net/Admin/Public/GetImage.ashx?Image=/Files/Images/media_assets/products/product_images/CBRspaceLFA-1slash2_Purified_CD18_Antibody_FC_010815.jpg&Width=240&Height=300&altFmImage_path=&Compression=90&Crop=5)
-
Human peripheral blood lymphocytes were stained with purified CD18 (clone CBR LFA1/2) (filled histogram), or purified mouse IgG1, κ isotype control (open histogram), and was then followed by anti-mouse IgG FITC.
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
366302 | 100 µg | 104€ |
CD18, also known as integrin β2 subunit, LFA-1 β subunit, and β2 integrin, is a 90 - 95 kD type I glycoprotein. CD18 non-covalently associates with CD11a, CD11b, or CD11c. CD18 is expressed on all leukocytes. CD18 and associated α chains function in the adhesion and signaling in hematopoietic cells.
Product DetailsProduct Details
- Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Purified human LFA-1
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
-
Additional reported applications (for the relevant formats of this clone) include: activation of LFA-1 and MAC-11,2. The LEAF™ or Ultra-LEAF™ purified antibody (Endotoxin < EU/µg, Azide-Free, 0.2 µm filtered) is recommended for function assays (contact our custom solutions team).
- Application References
-
- Petruzzelli L, et al. 1995. J. Immunol. 155:854. (Activ)
- Lu C, et al. 2001. J. Immunol. 166:5629. (Activ)
- Product Citations
- RRID
-
AB_2565276 (BioLegend Cat. No. 366302)
Antigen Details
- Structure
- 90 - 95 kD type I transmembrane glycoprotein.
- Distribution
-
Leukocytes.
- Function
- Cell adhesion and signaling.
- Interaction
- Integrin, type I transmembrane glycoprotein, associates with CD11a, CD11b, or CD11c
- Ligand/Receptor
- ICAMs.
- Cell Type
- Leukocytes
- Biology Area
- Immunology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Anderson DC, et al. 1987. Annu. Rev. Med. 38:175.
2. Springer TA. 1994. Cell 76:301. - Gene ID
- 3689 View all products for this Gene ID
- UniProt
- View information about CD18 on UniProt.org
Customers Also Purchased
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
Follow Us