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- Clone
- HM36 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- FAT, gpIIIb, gpIV
- Isotype
- Armenian Hamster IgG
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
Thioglycolate-elicited BALB/c mouse peritoneal macrophages stained with purified HM36, followed by anti-Armenian hamester IgG FITC
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 102602 | 500 µg | 207€ | ||||
CD36 is a 85 kD glycoprotein, also known as FAT, gpIIIb, or gpIV. It is a member of the class B scavenger receptor family, expressed on platelets, monocytes, macrophages, megakaryocytes, microvasculature, dendritic cells and mammary endothelial cells. The primary ligands for CD36 have been reported to be oxidized low density lipoprotein, anionic phospholipids, and collagens I, IV, and V. CD36 acts as a scavenger receptor thus promoting the removal of apoptotic neutrophils and other apoptotic bodies, as well as clearance of defective erythrocytes.
Product DetailsProduct Details
- Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Armenian Hamster
- Immunogen
- Full length version of the protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application References
-
- Hamilton R F, 2006. J. Biol. Chem. 281:34218.
- Stuart L M, 2007. J. Biol. Chem. doi:10.1074/jbc.M702887200.
- Hu Q, 2018. Nat Biomed Eng. 2(11): 831.
- Product Citations
- RRID
-
AB_312921 (BioLegend Cat. No. 102602)
Antigen Details
- Structure
- Scavenger receptor superfamily, 85 kD
- Distribution
-
Platelets, monocytes, macrophages, microvascular and mammary endothelial cells
- Function
- Scavenger receptor, recognition and phagocytosis of apoptotic neutrophils, adhesion
- Ligand/Receptor
- Oxidized low density lipoprotein, anionic phospholipids, collagen I, IV, and V
- Cell Type
- Endothelial cells, Macrophages, Monocytes, Platelets
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules
- Antigen References
-
1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Greenwalt DE, et al. 1992. Blood 80:1105.
3. Endemann G, et al. 1993. J. Biol. Chem. 268:11811. - Gene ID
- 12491 View all products for this Gene ID
- UniProt
- View information about CD36 on UniProt.org
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