- Clone
- 14C2A07 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- CLEC15A, MAFA-L, MAFA-2F1, MAFA-LIKE, 2F1
- Isotype
- Mouse IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
![14C2A07_A488_KLRG1_Antibody_100821.png 14C2A07_A488_KLRG1_Antibody_100821.png](https://d1spbj2x7qk4bg.cloudfront.net/Admin/Public/GetImage.ashx?Image=/Files/Images/media_assets/products/product_images/14C2A07_A488_KLRG1_Antibody_100821.png&Width=240&Height=300&altFmImage_path=&Compression=90&Crop=5)
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Human peripheral blood lymphocytes were stained with CD56 APC and KLRG1 (MAFA) (clone 14C2A07) Alexa Fluor® 488 (left) or mouse IgG2a, κ Alexa Fluor® 488 isotype control (right).
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
368615 | 25 tests | 176 CHF | ||||
368616 | 100 tests | 429 CHF |
Killer cell lectin-like receptor subfamily G member (KLRG1) is a 30 kD, type II membrane glycoprotein with one C-type lectin domain and one immunoreceptor tyrosine-based inhibitory motif (ITIM). KLRG1 is expressed by subsets of natural killer cells (NKs) and effector and memory T cells. It inhibits cell activation and proliferation and is also a marker of T cell senescence. The binding of KLRG1 to E-, N-, or R- cadherins blocks phosphorylation of AKT and increases the expression of cell cycle inhibitors.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human KLRG1-transfected cells.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 488 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
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FC - Quality tested
- Recommended Usage
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Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
* Alexa Fluor® 488 has a maximum emission of 519 nm when it is excited at 488 nm.
Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.
View full statement regarding label licenses - Excitation Laser
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Blue Laser (488 nm)
- RRID
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AB_2904403 (BioLegend Cat. No. 368615)
AB_2904403 (BioLegend Cat. No. 368616)
Antigen Details
- Structure
- Type II membrane glycoprotein, one C-type lectin domain, one ITIM, 30 kD.
- Distribution
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Subsets of natural killer cells, effector and memory T cells.
- Function
- Inhibits cell activation and proliferation
- Interaction
- AKT.
- Ligand/Receptor
- E-, N-, R- cadherins.
- Cell Type
- NK cells, T cells
- Biology Area
- Immunology
- Antigen References
-
1. Shi L, et al. 2014. J. Immunol. 192:649.
- Gene ID
- 10219 View all products for this Gene ID
- UniProt
- View information about KLRG1 on UniProt.org
Related Pages & Pathways
Pages
Other Formats
View All KLRG1 (MAFA) Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-human KLRG1 (MAFA) | 14C2A07 | FC |
Brilliant Violet 421™ anti-human KLRG1 (MAFA) | 14C2A07 | FC |
APC anti-human KLRG1 (MAFA) | 14C2A07 | FC |
PerCP/Cyanine5.5 anti-human KLRG1 (MAFA) | 14C2A07 | FC |
PE anti-human KLRG1 (MAFA) | 14C2A07 | FC |
PE/Dazzle™ 594 anti-human KLRG1 (MAFA) | 14C2A07 | FC |
PE/Cyanine7 anti-human KLRG1 (MAFA) | 14C2A07 | FC |
Alexa Fluor® 488 anti-human KLRG1 (MAFA) Antibody | 14C2A07 | FC |
Alexa Fluor® 647 anti-human KLRG1 (MAFA) | 14C2A07 | FC |
APC/Fire™ 810 anti-human KLRG1 (MAFA) | 14C2A07 | FC |
Brilliant Violet 785™ anti-human KLRG1 (MAFA) | 14C2A07 | FC |
APC/Fire™ 750 anti-human KLRG1 (MAFA) | 14C2A07 | FC |
Spark Red™ 718 anti-human KLRG1 (MAFA) (Flexi-Fluor™) | 14C2A07 | FC |
Brilliant Violet 605™ anti-human KLRG1 (MAFA) | 14C2A07 | FC |
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with purifie... -
Brilliant Violet 421™ anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with CD56 PE... -
APC anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with CD56 PE... -
PerCP/Cyanine5.5 anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with CD56 AP... -
PE anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with CD56 AP... -
PE/Dazzle™ 594 anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with CD56 AP... -
PE/Cyanine7 anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with CD56 Pa... -
Alexa Fluor® 488 anti-human KLRG1 (MAFA) Antibody
Human peripheral blood lymphocytes were stained with CD56 AP... -
Alexa Fluor® 647 anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with anti-hu... -
APC/Fire™ 810 anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with anti-hu... -
Brilliant Violet 785™ anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with anti-hu... -
APC/Fire™ 750 anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with anti-hu... -
Spark Red™ 718 anti-human KLRG1 (MAFA) (Flexi-Fluor™)
-
Brilliant Violet 605™ anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with anti-hu...
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