- Clone
- S17009F (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Interleukin 10 receptor subunit beta, CRFB4, CRF2-4, D21S58, D21S66, CDW210B
- Isotype
- Mouse IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
![S17009F_PE_CD210b_Antibody_041819 S17009F_PE_CD210b_Antibody_041819](https://d1spbj2x7qk4bg.cloudfront.net/Admin/Public/GetImage.ashx?Image=/Files/Images/media_assets/products/product_images/S17009F_PE_CD210b_Antibody_041819.png&Width=240&Height=300&altFmImage_path=&Compression=90&Crop=5)
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Human peripheral blood lymphocytes were stained with HLA-DR PerCP and CD210b (IL-10RB) (clone S17009F) PE (left) or mouse IgG2a, κ PE isotype control (right).
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
396803 | 25 tests | 153 CHF | ||||
396804 | 100 tests | 360 CHF |
CD210b is a Type 1 transmembrane glycoprotein also known as, subunit 2 (IL-10R2) and is an essential chain for the IL-10 receptor complex. The IL-10 receptor complex is made up of alpha (IL10-RA) and beta (IL-10RB) subunits. Coexpression of these subunits has been shown to be required for IL10 induced signal transduction. Binding of dimeric IL-10 to two alpha subunits can cause the recruitment of two beta subunits resulting in the transduction of the intracellular JAK/STAT pathway.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human IL10RB-transfected cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
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FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
- Excitation Laser
-
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- RRID
-
AB_2810607 (BioLegend Cat. No. 396803)
AB_2810608 (BioLegend Cat. No. 396804)
Antigen Details
- Structure
- Type 1 transmembrane glycoprotein belonging to the cytokine receptor family.
- Distribution
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CD210b is expressed by a variety of cell types including T cells, B cells, NK cells, monocytes and macrophages.
- Function
- Activates STAT1, STAT3, Jak1, Tyk and is a component of cytokine receptor complexes specific for IL-22, IL-26, IL-28, and IL-29.
- Ligand/Receptor
- IL-10
- Cell Type
- B cells, Macrophages, NK cells, T cells, Thymocytes
- Biology Area
- Adaptive Immunity, Immunology, Signal Transduction
- Molecular Family
- Cytokine/Chemokine Receptors
- Antigen References
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- Donnelly RP, et al. 2004. J Leukoc Biol. 76(2):314-321.
- Koppelman B, et al. 1997. Immunity. (6): 861-871
- Kotenko SV, et al. 1997. EMBO J. 16(19):5894-5903.
- Liu Y, et al. 1995. J Immunol. 152(4):1821-1829.
- Gene ID
- 3588 View all products for this Gene ID
- UniProt
- View information about CD210b on UniProt.org
Related FAQs
- What type of PE do you use in your conjugates?
- We use R-PE in our conjugates.
Other Formats
View All CD210b Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
PE anti-human CD210b (IL-10RB) | S17009F | FC |
Purified anti-human CD210b (IL-10RB) | S17009F | FC |
APC anti-human CD210b (IL-10RB) | S17009F | FC |
PE/Cyanine7 anti-human CD210b (IL-10RB) | S17009F | FC |
PE/Dazzle™ 594 anti-human CD210b (IL-10RB) | S17009F | FC |
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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PE anti-human CD210b (IL-10RB)
Human peripheral blood lymphocytes were stained with HLA-DR ... -
Purified anti-human CD210b (IL-10RB)
Human peripheral blood lymphocytes were stained CD210B (IL-1... -
APC anti-human CD210b (IL-10RB)
Human peripheral blood lymphocytes were stained with HLA-DR ... -
PE/Cyanine7 anti-human CD210b (IL-10RB)
Human peripheral blood lymphocytes were stained with anti-hu... -
PE/Dazzle™ 594 anti-human CD210b (IL-10RB)
Human peripheral blood lymphocytes were stained with anti-hu...
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