- Clone
- 34-7.Rec (See other available formats)
- Regulatory Status
- RUO
- Other Names
- BTF5, BT3.1, CD277, BTN3.1
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
![34-7Rec_PE_CD277_Antibody_010824 34-7Rec_PE_CD277_Antibody_010824](https://d1spbj2x7qk4bg.cloudfront.net/Admin/Public/GetImage.ashx?Image=/Files/Images/media_assets/products/product_images/34-7Rec_PE_CD277_Antibody_010824-.png&Width=240&Height=300&altFmImage_path=&Compression=90&Crop=5)
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Human peripheral blood lymphocytes were stained with anti-human CD277 (BTN3A1) Recombinant (clone 34-7.Rec) PE (filled histogram) or mouse IgG1, κ PE isotype control (open histogram).
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
383207 | 25 tests | 145 CHF | ||||
383208 | 100 tests | 325 CHF |
Butyrophilin 3A1 (BTN3A1), also known as CD277, is a 56 kD type 1 transmembrane glycoprotein. It belongs to the butyrophilin (BT)/B7 family and is expressed in various immune cells including T cells, B cells, Nk cells, monocytes, dendritic cells, endothelial cells, and some tumor cells. It plays a role in T-cell activation and in the adaptive immune response, and regulates the proliferation of activated T-cells and the release of cytokines and IFNƳ by activated T-cells.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Recombinant
- Host Species
- Mouse
- Immunogen
- pRC-CMV-BTN3A3
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
-
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- RRID
-
AB_3097513 (BioLegend Cat. No. 383207)
AB_3097513 (BioLegend Cat. No. 383208)
Antigen Details
- Structure
- 56 kD single pass type I membrane glycoprotein, member of the immunoglobin superfamily
- Distribution
-
Cell membrane
- Function
- Signaling receptor binding, Homodimerization
- Interaction
- TFF1, PEPL, BT3A2, G5E9A7
- Biology Area
- Immuno-Oncology, Inhibitory Molecules
- Molecular Family
- CD Molecules, Tumor Suppressors
- Antigen References
-
- Vantourout P, et al. 2018. PNAS. 115:1039-1044.
- Payne K, et al. 2020. Science. 369: 942-949.
- Rigau M, et lat. 2020. Science. 367:eaay5516.
- Yang Y, et al. 2019. Immunity. 50:1043-1053.
- Gene ID
- 11119 View all products for this Gene ID
- UniProt
- View information about CD277 on UniProt.org
Related Pages & Pathways
Pages
Related FAQs
- What type of PE do you use in your conjugates?
- We use R-PE in our conjugates.
Other Formats
View All CD277 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-human CD277 (BTN3A1) Recombinant Antibody | 34-7.Rec | FC |
APC anti-human CD277 (BTN3A1) Recombinant Antibody | 34-7.Rec | FC |
PE/Cyanine7 anti-human CD277 (BTN3A1) Recombinant Antibody | 34-7.Rec | FC |
PE anti-human CD277 (BTN3A1) Recombinant Antibody | 34-7.Rec | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human CD277 (BTN3A1) Recombinant Antibody
Human peripheral blood lymphocytes were stained with purifie... -
APC anti-human CD277 (BTN3A1) Recombinant Antibody
Human peripheral blood lymphocytes were stained with anti-hu... -
PE/Cyanine7 anti-human CD277 (BTN3A1) Recombinant Antibody
Human peripheral blood lymphocytes were stained with anti-hu... -
PE anti-human CD277 (BTN3A1) Recombinant Antibody
Human peripheral blood lymphocytes were stained with anti-hu...
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