Loading...

PerCP/Cyanine5.5 anti-mouse/human CD11b Antibody

Pricing & Availability
Clone
M1/70 (See other available formats)
Regulatory Status
RUO
Other Names
αM integrin, Mac-1, Mo1, CR3, Ly-40, C3biR, ITGAM
Isotype
Rat IgG2b, κ
Ave. Rating
Submit a Review
Product Citations
publications
M1slash70_PerCPCyanine55_CD11b_Antibody_111918
C57BL/6 splenocytes were blocked with TruStain FcX™ (anti-mouse CD16/32) Antibody then stained with Ly-6G/Ly-6C (Gr-1) APC and CD11b (clone M1/70) PerCP/Cyanine5.5 (left) or rat IgG2b, κ PerCP/Cyanine5.5 isotype control (right).
  • M1slash70_PerCPCyanine55_CD11b_Antibody_111918
    C57BL/6 splenocytes were blocked with TruStain FcX™ (anti-mouse CD16/32) Antibody then stained with Ly-6G/Ly-6C (Gr-1) APC and CD11b (clone M1/70) PerCP/Cyanine5.5 (left) or rat IgG2b, κ PerCP/Cyanine5.5 isotype control (right).
Compare all formats See PerCP/Cyanine5.5 spectral data
Cat # Size Price Quantity Check Availability Save
101227 25 µg 72€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
101228 100 µg 234€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse, Human, Cynomolgus, Rhesus
Reported Reactivity
Chimpanzee, Baboon, Rabbit
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
C57BL/10 splenocytes
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PerCP/Cyanine5.5 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The CD11b antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is = 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

* PerCP/Cyanine5.5 has a maximum absorption of 482 nm and a maximum emission of 690 nm.

Excitation Laser
Blue Laser (488 nm)
Application Notes

Clone M1/70 has been verified for immunocytochemistry (ICC) and frozen immunohistochemistry (IHC-F).

Additional reported applications (for relevant formats of this clone) include: immunoprecipitation1,4, in vitro blocking3,9,12, depletion2,8, immunofluorescence microscopy6,7,10, immunohistochemistry of acetone-fixed frozen sections5,11-13, and spatial biology (IBEX)35,36. For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) (Cat. No. 101248).

Additional Product Notes
BioLegend is in the process of converting the name PerCP/Cy5.5 to PerCP/Cyanine5.5. The dye molecule remains the same, so you should expect the same quality and performance from our PerCP/Cyanine5.5 products. Contact Technical Service if you have any questions.
Application References

(PubMed link indicates BioLegend citation)
  1. Springer T, et al. 1978. Eur. J. Immunol. 8:539. (IP)
  2. Ault K and Springer T. 1981. J. Immunol. 126:359. (Deplete)
  3. Springer TA, et al. 1982. Immunol. Rev. 68:171. (Block)
  4. Ho MK and Springer TA. 1983. J. Biol. Chem. 258:2766. (IP)
  5. Flotte TJ, et al. 1983. Am. J. Pathol. 111:112. (IHC)
  6. Noel GJ, et al. 1990. J. Clin. Invest. 85:208. (IF)
  7. Allen LA and Aderem A. 1996. J. Exp. Med. 184:627 (IF)
  8. D'Amico A and Wu L. 2003. J. Exp. Med. 198:293. (Deplete)
  9. Brickson SJ, et al. 2003. Appl Physiol. 95:969. (Block)
  10. Clatworthy MR and Smith KG. 2004. J. Exp. Med. 199:717. (IF)
  11. Hata H, et al. 2004. J. Clin. Invest. 114:582. (IHC)
  12. Zhang Y, et al. 2002. J. Immunol. 168:3088. (IHC)
  13. Iwasaki A and Kelsall BL. 2001. J. Immunol. 166:4884 (IHC, FC)
  14. Tailleux L. 2003. J. Exp. Med. 197:121. (Block, FC)
  15. Olver S, et al. 2006. Cancer Research 66:571. (FC)
  16. Tan SL, et al. 2006. J. Immunol. 176:2872. (FC) PubMed
  17. Ponomarev ED, et al. 2006. J. Immunol. 176:1402. (FC)
  18. Dzhagalov I, et al. 2007. Blood 109:1620. (FC)
  19. Fazilleau N, et al. 2007. Nature Immunol. 8:753.
  20. Rasmussen JW, et al. 2006. Infect. Immun.74:6590. PubMed
  21. Napimoga MH, et al. 2008. J. Immunol. 180:609. PubMed
  22. Elqaraz-Carmon V, et al. 2008. J. Lipid. Res. 49:1894. PubMed
  23. Kim DD, et al. 2008. Blood 112:1109. PubMed
  24. Guo Y, et al. 2008. Blood 112:480. PubMed
  25. Norian LA, et al. 2009. Cancer Res. 69:3086. (FC) PubMed
  26. Baumgartner CK, et al. 2010. J. Immunol. 184:573. PubMed
  27. Charles N, et al. 2010. Nat. Med. 16:701. (FC) PubMed
  28. Whiteland J, et al. 1995. J. Histochem. Cytochem. 43:313. (IHC)
  29. Weber GF, et al. 2014. J Exp Med. 211:1243. PubMed
  30. Ashok A, et al. 2015. Toxicol Sci. 143:64. PubMed
  31. Price PJ, et al. 2015. J Immunol. 194:1164. PubMed
  32. Doni A, et al. 2015. J Exp Med. 212:905. PubMed
  33. Ferreira R, et al. 2016. J Infect Dis. 213: 669 - 673. PubMed
  34. Peterson VM, et al. 2017. Nat. Biotechnol. 35:936. (PG)
  35. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  36. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Milasan A, et al. 2017. J Am Heart Assoc. 10.1161/JAHA.117.006892. PubMed
  2. Hou X, et al. 2020. Cell Reports. 28(1):172-189.e7.. PubMed
  3. Lang J, et al. 2020. Nat Commun. 11:1338. PubMed
  4. Gordan S, et al. 2020. Cell Reports. 29(10):3033-3046.e4.. PubMed
  5. Lee T, et al. 2014. Mol Biol Cell. 25:583. PubMed
  6. Guo H, Cooper S, Friedman A, et al. 2017. PLoS One. 10.1371/journal.pone.0150809. PubMed
  7. Orberg E, et al. 2016. Mucosal Immunol. 10.1038/mi.2016.53. PubMed
  8. Liu Y, et al. 2021. Cell Metabolism. 33(6):1221-1233.e11. PubMed
  9. Shah D, et al. 2021. Oncoimmunology. 10:1939601. PubMed
  10. Zhou R, et al. 2022. EBioMedicine. 75:103762. PubMed
  11. Grandjean CL, et al. 2021. Sci Adv. 7:. PubMed
  12. Leslie J, et al. 2021. Sci Rep. 11:1415. PubMed
  13. Zheng J, et al. 2022. Front Pharmacol. 13:866228. PubMed
  14. Zhu Y, et al. 2022. Nat Commun. 13:4282. PubMed
  15. Tian WJ, et al. 2021. Clin Exp Pharmacol Physiol. 48:902. PubMed
  16. Ferrao Blanco MN, et al. 2022. Br J Pharmacol. 179:2771. PubMed
  17. Osokine I, et al. 2022. Cell Rep. 38:110329. PubMed
  18. Agarwalla P, et al. 2022. Nat Biotechnol. 40:1250. PubMed
  19. Chae CS, et al. 2022. Cancer Discov. 12:1904. PubMed
  20. Yang K, et al. 2022. Sci Immunol. 7:eabn2888. PubMed
  21. Marquardt RM, et al. 2022. Int J Mol Sci. 23: . PubMed
  22. Halin C, et al. 2022. EMBO J. 41:e111528. PubMed
  23. Auguste YSS, et al. 2022. Nat Neurosci. 25:1273. PubMed
  24. Schepers M, et al. 2023. Brain Behav Immun. 109:1. PubMed
  25. García-García A, et al. 2023. Bioact Mater. 24:174. PubMed
  26. Glaubitz J, et al. 2023. Gut. :. PubMed
  27. Zhang K, et al. 2023. Nat Metab. 5:129. PubMed
  28. Arimoto KI, et al. 2023. Nat Commun. 14:251. PubMed
  29. Zhang B, et al. 2023. Signal Transduct Target Ther. 8:28. PubMed
  30. Lazure F, et al. 2023. Nat Commun. 14:535. PubMed
  31. Murakata Y, et al. 2023. Front Cardiovasc Med. 9:1075358. PubMed
  32. Meng S, et al. 2023. Stem Cell Investig. 10:2. PubMed
  33. Drummer C, et al. 2023. Front Immunol. 14:1113883. PubMed
  34. Li Z, et al. 2022. Nat Commun. 13:1845. PubMed
  35. Wilden A, et al. 2022. Front Immunol. 13:991295. PubMed
  36. Peng W, et al. 2022. Cell Mol Life Sci. 79:602. PubMed
  37. Chen H, et al. 2023. Nat Commun. 14:941. PubMed
  38. Zhu S, et al. 2023. J Nanobiotechnology. 21:81. PubMed
  39. Guo D, et al. 2023. Cell Biosci. 13:51. PubMed
  40. Kozlovski S, et al. 2023. Front Immunol. 13:1041552. PubMed
  41. Do-Thi VA, et al. 2023. Cancer Res Commun. 3:80. PubMed
  42. Shen Z, et al. 2023. iScience. 26:106572. PubMed
  43. Haensel D, et al. 2023. Nat Commun. 14:2685. PubMed
  44. John S, et al. 2020. Sci Rep. 10:11377. PubMed
  45. Hastings AK, et al. 2019. iScience. 13:339. PubMed
  46. McNamara HA, et al. 2020. Cell Host Microbe. 572:28. PubMed
  47. Bouchareychas L, et al. 2021. iScience. 24(8):102847. PubMed
  48. Gern BH, et al. 2021. Cell Host Microbe. 29(4):594-606.e6. PubMed
  49. Kaczanowska S, et al. 2021. Cell. 184(8):2033-2052.e21. PubMed
  50. Kim SS, et al. 2022. Cancers (Basel). 14:. PubMed
  51. Hofmann I, et al. 2022. J Pharmacol Exp Ther. Online ahead of print. PubMed
  52. Huang X, et al. 2021. Stem Cells Int. 2021:8138374. PubMed
  53. Hong M, et al. 2021. Int J Mol Sci. 22:. PubMed
  54. Li X, et al. 2022. Nat Commun. 13:2794. PubMed
  55. Zhao X, et al. 2022. Front Mol Biosci. 9:786864. PubMed
  56. Meng W, et al. 2021. JCI Insight. 6:. PubMed
  57. Ortiz G, et al. 2020. Front Immunol. 11:1713. PubMed
  58. Postat J et al. 2018. Immunity. 49(4):654-665 . PubMed
  59. Fu B et al. 2017. Immunity. 47(6):1100-1113 . PubMed
  60. Chen L, et al. 2019. Cell Mol Gastroenterol Hepatol. 7:623. PubMed
  61. Kenichi Shimada et al. 2018. Immunity. 49(5):873-885 . PubMed
  62. Kobayashi T, et al. 2019. Cell. 176:982. PubMed
  63. Zasłona Z, et al. 2014. J Immunol. 193:4245. PubMed
  64. Leach SM, et al. 2020. Cell Rep. 33:108337. PubMed
  65. Dong L, et al. 2021. Cancer Cell. . PubMed
  66. Shen Y, et al. 2021. Comput Struct Biotechnol J. 19:5360. PubMed
  67. Súarez-López L, et al. 2021. iScience. 24:103406. PubMed
  68. Bauer KM, et al. 2022. JCI Insight. 7:. PubMed
  69. Yuzhu Hou et al. 2018. Immunity. 49(3):490-503 . PubMed
  70. Hirano KI, et al. 2021. eLife. 0.416666666666667. PubMed
  71. Yuan Q, et al. 2021. Cell Reports. 34(5):108724. PubMed
  72. Zheng H, et al. 2021. Frontiers in Cell and Developmental Biology. 9:641527. PubMed
  73. Amano C, et al. 2015. PLoS One. 10: 0137207. PubMed
  74. Sun P, et al. 2015. J Hepatol. . PubMed
  75. Yang X, et al. 2020. Blood Sci. 2:89. PubMed
  76. Castellanos CA, et al. 2021. Sci Immunol. 6:eabh0707. PubMed
  77. Tan X, et al. 2021. Front Oncol. 11:768222. PubMed
  78. Biswas S, et al. 2021. Nature. 591:464. PubMed
  79. Khandelwal P, et al. 2013. PLoS One. 8:64193. PubMed
  80. Neubert K, et al. 2014. J Immunol. 192:5830. PubMed
  81. Schiller M, et al. 2021. Immunity. 54(5):1022-1036.e8. PubMed
  82. Zhu B, et al. 2021. Immunity. 54(6):1200-1218.e9. PubMed
  83. Pan H, et al. 2020. Mol Psychiatry. . PubMed
  84. Nguyen SL, et al. 2021. Sci Rep. 11:4217. PubMed
  85. Cai B, et al. 2021. Mol Cancer. 20:165. PubMed
  86. Glaubitz J, et al. 2022. Nat Commun. 13:4502. PubMed
  87. Xiong A, et al. 2022. EBioMedicine. 83:104239. PubMed
  88. Galle E, et al. 2022. Genome Biol. 23:207. PubMed
  89. Koh EH, et al. 2018. Diabetes. 67(12). PubMed
  90. Nakamura‐Ishizu A et al. 2018. Cell reports. 25(7):1772-1785 . PubMed
  91. Jiao H, et al. 2021. Cell. 184(11):2896-2910.e13. PubMed
  92. Lu S, et al. 2020. JCI Insight. 5:00. PubMed
  93. Anastasiou M, et al. 2021. JCI Insight. 6:. PubMed
  94. Parada-Kusz M, et al. 2018. Dis Model Mech. 11:. PubMed
  95. Plein A, et al. 2018. Nature. 562:223. PubMed
  96. Montel-Hagen A, et al. 2020. Cell Rep. 33:108320. PubMed
  97. Jeong SJ, et al. 2021. Autophagy. 17:3740. PubMed
  98. Fulham MA, et al. 2019. Am J Physiol Cell Physiol. 317:C687. PubMed
  99. Gu H, et al. 2018. Aging (Albany NY). 1.525694444. PubMed
  100. Cong J et al. 2018. Cell metabolism. 28(2):243-255 . PubMed
  101. JI B, et al. 2016. Cell Death Differ. 23:759-75. PubMed
  102. Bunn P, et al. 2014. J Immunol. 192:3709. PubMed
  103. Nishi C, et al. 2014. Mol Cell Biol. 34:1512. PubMed
  104. Xu G, et al. 2022. Cell Death Dis. 13:888. PubMed
  105. Raineri D, et al. 2021. Biomedicines. 10:. PubMed
  106. Park D, et al. 2020. Cancer Res. 80:4172. PubMed
  107. Yue X, et al. 2019. Nat Commun. 10:2011. PubMed
  108. Pereira JA, et al. 2020. Hum Mol Genet. 29:1253. PubMed
  109. Bretscher P, et al. 2015. EMBO Mol Med. 7:593. PubMed
  110. Hu J, et al. 2020. Theranostics. 7.154166667. PubMed
  111. Qi T, et al. 2020. Cell Rep. 33:108452. PubMed
  112. Bogie JF, et al. 2020. Ther Adv Chronic Dis. 11:2040622320947378. PubMed
  113. Nayak RR, et al. 2021. Cell Host Microbe. 29(3):362-377.e11. PubMed
  114. Zhang F, et al. 2020. EMBO Mol Med. e12034:12. PubMed
  115. Lu CY, et al. 2020. J Neurosci. 40:9602. PubMed
  116. Okamura T, et al. 2021. Front Immunol. 12:669629. PubMed
  117. Qian SJ, et al. 2021. Front Immunol. 12:711337. PubMed
  118. Wang J, et al. 2021. Nat Commun. 12:6198. PubMed
  119. Fennell LM, et al. 2020. EMBO J. 39:e103303. PubMed
  120. Guo P, et al. 2021. J Immunol. 207:408. PubMed
  121. Li W, et al. 2021. Front Pharmacol. 12:697483. PubMed
  122. Yu Y, et al. 2022. Nat Commun. 13:6857. PubMed
  123. Mishra BB, et al. 2017. Nat Microbiol. 2:17072. PubMed
  124. Uribesalgo I, et al. 2019. EMBO Mol Med. 11:e9266. PubMed
  125. Xu Z, et al. 2020. Cancer Immunol Res. 1354:8. PubMed
  126. Zhu H, et al. 2021. Cell Metabolism. :. PubMed
  127. Harb H, et al. 2021. Immunity. 54(6):1186-1199.e7. PubMed
  128. Tacconi C, et al. 2021. Cell Reports. 35(2):108993. PubMed
  129. Lu S, et al. 2020. Arterioscler Thromb Vasc Biol. 40:394. PubMed
  130. Sun L, et al. 2015. J Immunol. 194:4891. PubMed
  131. Wei W, et al. 2022. mSystems. 7:e0046922. PubMed
  132. , et al. 2021. Eur J Immunol. 51:2708. PubMed
  133. Zuo W, et al. 2022. Cell Death Discov. 8:257. PubMed
  134. Xu M, et al. 2022. Genes Dis. 9:429. PubMed
  135. Chung L et al. 2018. Cell host & microbe. 23(2):203-214 . PubMed
  136. Sasaki T, et al. 2020. Cell Reports. 28(1):202-217.e7.. PubMed
  137. Deczkowska A, et al. 2017. Nat Commun. 8:717. PubMed
  138. Sharma A, et al. 2020. Cell. 183(2):377-394.e21. PubMed
  139. Liu Z, et al. 2021. Immunity. 54(2):247-258.e7. PubMed
  140. Huang Z, et al. 2021. Nat Commun. 12:145. PubMed
  141. Carbone C, et al. 2021. J Immunother Cancer. 9:. PubMed
  142. Dagher T, et al. 2021. J Exp Med. 218:. PubMed
  143. Anger-Góra N, et al. 2021. Oncol Lett. 22:582. PubMed
  144. Coronel MM, et al. 2020. Sci Adv. 6:eaba5573. PubMed
  145. Kyburz A, et al. 2019. J Allergy Clin Immunol. 143:1496. PubMed
  146. Lin W, et al. 2019. EBioMedicine. 49:133. PubMed
  147. Sendler M, et al. 2020. Gastroenterology. 158:253. PubMed
  148. Brown SM et al. 2017. Endocrinology. 158(10):3592-3604 . PubMed
  149. López MJ, et al. 2018. Invest Ophthalmol Vis Sci. 59:5671. PubMed
  150. Sydney Lavoie et al. 2019. eLife. 8 pii: e39982. PubMed
  151. Covarrubias AJ, et al. 2020. Nat Metab. 1265:2. PubMed
  152. Stowe CL, et al. 2019. eLife. 0.333333333333333. PubMed
  153. Chatterjee D, et al. 2021. Cell Reports. 35(2):108996. PubMed
  154. Grauel AL, et al. 2020. Nat Commun. 4.84375. PubMed
  155. Wu S, et al. 2022. BMC Immunol. 23:17. PubMed
  156. Rashid MH, et al. 2021. Oncol Rep. 45:1171. PubMed
  157. Zhao D, et al. 2020. Cancer Discov. 10:1374. PubMed
  158. Cruz-Herranz A, et al. 2021. JCI Insight. 6: . PubMed
  159. Gubin MM, et al. 2018. Cell. 175:1014. PubMed
  160. Wang Z et al. 2018. Immunity. 49(1):80-92 . PubMed
  161. Bhattacharya A, et al. 2018. Neuropsychopharmacology. 43:2586. PubMed
  162. Carestia A, et al. 2019. Cell Rep. 28:896. PubMed
  163. Wei Z, et al. 2021. Nat Commun. 0.805555556. PubMed
  164. Hu Y, et al. 2021. Cell Death Dis. 12:743. PubMed
  165. Chruewkamlow N, et al. 2021. Stem Cell Res Ther. 12:520. PubMed
  166. Vachon L, et al. 2022. Theranostics. 12:1440. PubMed
  167. Ali S, et al. 2021. PLoS One. 16:e0246646. PubMed
  168. Bravo-Caparrós I, et al. 2020. FASEB J. 34:5951. PubMed
  169. Ni C, et al. 2021. Infect Immun. 89:. PubMed
  170. Pandit M, et al. 2021. Eur J Immunol. 51:1461. PubMed
  171. Han Y, et al. 2022. Int J Biol Sci. 18:5653. PubMed
  172. Dulken BW, et al. 2019. Nature. 571:205. PubMed
  173. Muri J, et al. 2020. eLife. 9:e53627.. PubMed
  174. Winchell CG, et al. 2020. Front Immunol. 1.077083333. PubMed
  175. Yu JM, et al. 2019. Nat Commun. 4.388888889. PubMed
  176. Hightower RM, et al. 2019. Mol Ther. 28:189. PubMed
  177. Xueyang Yu et al. 2017. Immunity. 47(5):903-912 . PubMed
  178. Bitschar K, et al. 2019. Nat Commun. 10:2730. PubMed
  179. Chen Z, et al. 2019. Mol Med Rep. 19:3210. PubMed
  180. Tozuka M, et al. 2016. J Dermatol Sci. 82: 38-45. PubMed
  181. Sharif O, et al. 2013. J Immunol. 190:5640. PubMed
  182. Matsumura T, et al. 2022. Nat Commun. 13:7064. PubMed
  183. Hsu M, et al. 2022. Nat Immunol. 23:581. PubMed
  184. Sakamoto K, et al. 2021. Immunity. 54:2321. PubMed
  185. Raoof R, et al. 2021. J Neurosci. 41:8249. PubMed
  186. Guo D, et al. 2022. Bone Res. 10:45. PubMed
  187. Bennett FC, et al. 2018. Neuron. 98:1170. PubMed
  188. Yang X, et al. 2018. Sci Rep. 8:188. PubMed
  189. Draijer C, et al. 2018. Sci Rep. 8:5105. PubMed
  190. Nagashima H et al. 2019. Immunity. 51(4):682-695 . PubMed
  191. Alexander Mildner et al. 2017. Immunity. 46(5):849-862 . PubMed
  192. Yousef H, et al. 2019. Nat Med. 25:988. PubMed
  193. Liu YG, et al. 2019. FASEB J. 33:5018. PubMed
  194. Da Mesquita S, et al. 2021. Science Advances. 7(21):. PubMed
  195. Unsinger J, et al. 2021. J Leukoc Biol. 109:697. PubMed
  196. Chen M, et al. 2019. Cell Stem Cell. 25:501. PubMed
  197. Muri J, et al. 2020. Cell Reports. 29(9):2731-2744.e4.. PubMed
  198. Muchenditsi A, et al. 2017. Am J Physiol Gastrointest Liver Physiol. 313:G39. PubMed
  199. Tothova Z et al. 2017. Cell stem cell. 21(4):547-555 . PubMed
  200. Chen C, et al. 2020. Cell Rep. 2136:30. PubMed
  201. Dallari S, et al. 2021. Cell Host Microbe. 29(6):1014-1029.e8. PubMed
  202. Lazarian G, et al. 2021. Cancer Cell. 39(3):380-393.e8. PubMed
  203. Rustenhoven J, et al. 2021. Cell. 184(4):1000-1016.e27. PubMed
  204. Liao Y, et al. 2020. Theranostics. 7.113888889. PubMed
  205. Zhu K, et al. 2022. EMBO Rep. 23:e54499. PubMed
  206. Ding R, et al. 2022. J Neuroinflammation. 19:137. PubMed
  207. Xu JL, et al. 2022. Front Pharmacol. 13:911663. PubMed
  208. Leary N, et al. 2022. J Extracell Vesicles. 11:e12197. PubMed
  209. Hakim R, et al. 2021. J Neurosci. 41:8441. PubMed
  210. Gu H, et al. 2021. Elife. 10:. PubMed
  211. Kiss M, et al. 2020. Cancer Immunol Res. 9:309. PubMed
  212. Starr T, et al. 2018. PLoS One. 13:e0193601. PubMed
  213. Ding L et al. 2018. Cell reports. 25(11):2972-2980 . PubMed
  214. Zegarra‐Ruiz DF et al. 2018. Cell host & microbe. 25(1):113-127 . PubMed
  215. Meng Michelle Xu et al. 2017. Immunity. 47(2):363-373 . PubMed
  216. Jaitin DA et al. 2016. Cell. 167(7):1883-1896 . PubMed
  217. Zhang J, et al. 2018. Oncoimmunology. 7:e1461301. PubMed
  218. Montes de Oca M, et al. 2016. PLoS Pathog. 12: 1005398. PubMed
  219. Chen J, et al. 2017. Sci Rep. 10.1038/s41598-017-00654-2. PubMed
  220. Danzer H, et al. 2020. Elife. 9:00. PubMed
  221. Xu W, et al. 2021. Immunity. 54(3):526-541.e7. PubMed
  222. Stefan KL, et al. 2020. Cell. 1312:183. PubMed
  223. Molgora M, et al. 2020. Cell. 182:886. PubMed
  224. Werner A, et al. 2021. iScience. 24:103076. PubMed
  225. Hackstein CP, et al. 2022. Nat Commun. 13:7472. PubMed
  226. Ramanan D, et al. 2020. Cell. 181(6):1276-1290. PubMed
  227. Lee C, et al. 2020. Front Immunol. 11:77. PubMed
  228. Bohlen CJ et al. 2017. Neuron. 94(4):759-773 . PubMed
  229. Luo H, et al. 2019. Cell Rep. 26:945. PubMed
  230. Ishihara J, et al. 2018. Nat Commun. 9:2163. PubMed
  231. Maulhardt HA, et al. 2020. Invest New Drugs. 1618:38. PubMed
  232. McDonald MM, et al. 2021. Cell. 184(5):1330-1347.e13. PubMed
  233. Baptista M, et al. 2016. Nat Commun. 7:12175. PubMed
  234. Guey B, et al. 2014. Proc Natl Acad Sci U S A. 111:17254. PubMed
  235. Peng V, et al. 2022. Nat Immunol. 23:619. PubMed
  236. Piirainen S, et al. 2021. Glia. 69:2459. PubMed
  237. Chen YL, et al. 2022. Front Neurosci. 16:876582. PubMed
  238. Sakamoto K, et al. 2022. STAR Protoc. 3:101052. PubMed
  239. Tummala G, et al. 2021. Invest Ophthalmol Vis Sci. 62:41. PubMed
  240. Maller O, et al. 2020. Nat Mater. 20:548. PubMed
  241. Peltzer N, et al. 2018. Nature. 557:112. PubMed
  242. Koyama M et al. 2019. Immunity. 51(5):885-898 . PubMed
  243. Lee J, et al. 2015. Nat Commun. 6: 8499. PubMed
  244. Sen D, et al. 2016. PLoS One. 11:e0165064. PubMed
  245. Liddelow S, et al. 2017. Nature. 541:481-487. PubMed
  246. Xu Z, et al. 2020. Cell Rep. 32:108041. PubMed
  247. Ang QY, et al. 2020. Cell. 181(6):1263-1275.e16. PubMed
  248. Zheng C, et al. 2021. J Extracell Vesicles. 10:e12109. PubMed
  249. Tripathi A, et al. 2021. Mol Psychiatry. 26:3043. PubMed
  250. Guo Y, et al. 2021. Nat Immunol. 22:746. PubMed
  251. Spiljar M, et al. 2021. Cell Metab. 33:2231. PubMed
  252. Zhang M, et al. 2022. iScience. 25:104490. PubMed
  253. Kastenschmidt JM, et al. 2021. Cell Rep. 35:108997. PubMed
  254. Pessoa Rodrigues C, et al. 2020. Sci Adv. 6:eaaz4815. PubMed
  255. Strattan E, et al. 2020. Frontiers in Immunology. 2.131944444. PubMed
  256. Ribechini E, et al. 2017. Blood Adv. 0.699305556. PubMed
  257. Tan DQ, et al. 2019. Cell Rep. 26:2316. PubMed
  258. Tong Y, et al. 2018. EBioMedicine. 39:132. PubMed
  259. Aurélien Trompette et al. 2018. Immunity. 48(5):992-1005 . PubMed
  260. Kapralov AA, et al. 2020. Nat Chem Biol. 278:16. PubMed
  261. Zheng H, et al. 2021. Frontiers in Immunology. 12:645100. PubMed
  262. Han J, et al. 2015. Cancer Res . 75: 5273 - 5282. PubMed
  263. Chithanathan K, et al. 2022. Biology (Basel). 11:. PubMed
  264. Wang Y, et al. 2022. Nat Cell Biol. 24:230. PubMed
  265. Erens C, et al. 2022. Biomedicines. 10:. PubMed
  266. Yang F, et al. 2021. Nat Commun. 12:3424. PubMed
RRID
AB_893233 (BioLegend Cat. No. 101227)
AB_893232 (BioLegend Cat. No. 101228)

Antigen Details

Structure
Integrin family, associates with integrin β2 (CD18), 170 kD
Distribution

Granulocytes, monocytes/macrophages, dendritic cells, NK cells, subsets of T and B cells

Function
Adhesion, chemotaxis
Ligand/Receptor
ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, fibrinogen
Cell Type
B cells, Dendritic cells, Granulocytes, Macrophages, Monocytes, Neutrophils, NK cells, T cells, Tregs
Biology Area
Cell Adhesion, Cell Biology, Costimulatory Molecules, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Springer TA. 1994. Cell 76:301.
3. Coxon A, et al. 1996. Immunity 5:653.

Gene ID
16409 View all products for this Gene ID 3684 View all products for this Gene ID
Specificity (DOES NOT SHOW ON TDS):
CD11b
Specificity Alt (DOES NOT SHOW ON TDS):
CD11b
App Abbreviation (DOES NOT SHOW ON TDS):
FC
UniProt
View information about CD11b on UniProt.org

Related FAQs

How stable is PerCP/Cyanine5.5 tandem as compared to PerCP alone?

PerCP/Cyanine5.5 is quite photostable and also better than PerCP alone in withstanding fixation.

Other Formats

View All CD11b Reagents Request Custom Conjugation
Description Clone Applications
APC anti-mouse/human CD11b M1/70 FC
Biotin anti-mouse/human CD11b M1/70 FC
FITC anti-mouse/human CD11b M1/70 FC
PE anti-mouse/human CD11b M1/70 FC,IHC
PE/Cyanine5 anti-mouse/human CD11b M1/70 FC
Purified anti-mouse/human CD11b M1/70 FC,CyTOF®,IP,IHC-F,ICC
PE/Cyanine7 anti-mouse/human CD11b M1/70 FC
Alexa Fluor® 488 anti-mouse/human CD11b M1/70 FC,IHC-F,3D IHC,SB
Alexa Fluor® 647 anti-mouse/human CD11b M1/70 FC,3D IHC,SB
Alexa Fluor® 700 anti-mouse/human CD11b M1/70 FC
Pacific Blue™ anti-mouse/human CD11b M1/70 FC
APC/Cyanine7 anti-mouse/human CD11b M1/70 FC
PerCP/Cyanine5.5 anti-mouse/human CD11b M1/70 FC
PerCP anti-mouse/human CD11b M1/70 FC
Brilliant Violet 421™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 570™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 605™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 650™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 711™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 785™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 510™ anti-mouse/human CD11b M1/70 FC,ICC
Ultra-LEAF™ Purified anti-mouse/human CD11b M1/70 FC,CyTOF®,IP,Block,Depletion,IHC-F,ICC
Purified anti-mouse/human CD11b (Maxpar® Ready) M1/70 FC,CyTOF®
Alexa Fluor® 594 anti-mouse/human CD11b M1/70 IHC-F,FC
PE/Dazzle™ 594 anti-mouse/human CD11b M1/70 FC
APC/Fire™ 750 anti-mouse/human CD11b M1/70 FC
TotalSeq™-A0014 anti-mouse/human CD11b M1/70 PG
Brilliant Violet 750™ anti-mouse/human CD11b M1/70 FC
TotalSeq™-B0014 anti-mouse/human CD11b M1/70 PG
TotalSeq™-C0014 anti-mouse/human CD11b M1/70 PG
Spark NIR™ 685 anti-mouse/human CD11b M1/70 FC
PE/Fire™ 640 anti-mouse/human CD11b M1/70 FC
Spark YG™ 593 anti-mouse/human CD11b M1/70 FC
Spark YG™ 570 anti-mouse/human CD11b M1/70 IHC-F
PE/Fire™ 810 anti-mouse/human CD11b M1/70 FC
APC/Fire™ 810 anti-mouse/human CD11b Antibody M1/70 FC
Spark Blue™ 550 anti-mouse/human CD11b M1/70 FC
Spark UV™ 387 anti-mouse/human CD11b M1/70 FC
PerCP/Fire™ 806 anti-mouse/human CD11b M1/70 FC
PerCP/Fire™ 780 anti-mouse/human CD11b M1/70 FC
Spark Blue™ 574 anti-mouse/human CD11b (Flexi-Fluor™) M1/70 FC
KIRAVIA Blue 520™ anti-mouse/human CD11b M1/70 FC
PE/Fire™ 744 anti-mouse/human CD11b M1/70 FC
Spark PLUS UV™ 395 anti-mouse/human CD11b M1/70 FC
Go To Top Version: 2    Revision Date: 11/19/2018

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

ProductsHere
Login / Register
Remember me
Forgot your password? Reset password?
Create an Account