- Clone
- S17015F (See other available formats)
- Regulatory Status
- RUO
- Other Names
- HB7, T10, ADP-ribosyl cyclase
- Isotype
- Mouse IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
![S17015F_A700_CD38_Antibody_033020 S17015F_A700_CD38_Antibody_033020](https://d1spbj2x7qk4bg.cloudfront.net/Admin/Public/GetImage.ashx?Image=/Files/Images/media_assets/products/product_images/S17015F_A700_CD38_Antibody_033020.png&Width=240&Height=300&altFmImage_path=&Compression=90&Crop=5)
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Human peripheral blood lymphocytes were stained with anti-human CD38 (clone S17015F) Alexa Fluor® 700 (filled histogram) or mouse IgG2a, κ Alexa Fluor® 700 isotype control (open histogram).
CD38 is a 45 kD type II transmembrane glycoprotein also known as T10. It is an ADP-ribosyl hydrolase expressed at variable levels on hematopoietic cells and in some non-hematopoietic tissues (such as brain, muscles, and kidney). In humans, it is expressed at high levels on plasma cells and activated T and B cells. By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, adhesion, and the metabolism of cADPR and NAADP. CD31 is the ligand of CD38.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human CD38 transfectants
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 700 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
* Alexa Fluor® 700 has a maximum emission of 719 nm when it is excited at 633 nm / 635 nm. Prior to using Alexa Fluor® 700 conjugate for flow cytometric analysis, please verify your flow cytometer's capability of exciting and detecting the fluorochrome.
Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.
View full statement regarding label licenses - Excitation Laser
-
Red Laser (633 nm)
- Application Notes
-
S17015F is able to cross-block binding of clones HIT2 and HB-7 also raised against human CD38, but not S17015A based on in-house testing.
- RRID
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AB_2860980 (BioLegend Cat. No. 397206)
Antigen Details
- Structure
- ADP-ribosyl cyclase, ectoenzyme, type II glycoprotein, 45 kD
- Distribution
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T cells, B cells, NK, myeloid, plasma, and dendritic cells
- Function
- Ecto-ADP-ribosyl cyclase, calcium signaling, cell activation
- Ligand/Receptor
- CD31, hyaluronic acid
- Cell Type
- B cells, Dendritic cells, NK cells, Plasma cells, T cells
- Biology Area
- Cell Adhesion, Cell Biology, Immunology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
- Ferrero E, et al. 1999. J Leuko Biol. 65:151.
- Lund F, et al. 1995. Immunol. Today 16:469.
- Gene ID
- 952 View all products for this Gene ID
- UniProt
- View information about CD38 on UniProt.org
Related FAQs
Other Formats
View All CD38 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
PE anti-human CD38 | S17015F | FC |
FITC anti-human CD38 | S17015F | FC |
APC/Fire™ 750 anti-human CD38 | S17015F | FC |
Purified anti-human CD38 | S17015F | FC |
Alexa Fluor® 700 anti-human CD38 | S17015F | FC |
PerCP/Cyanine5.5 anti-human CD38 | S17015F | FC |
PE/Cyanine7 anti-human CD38 | S17015F | FC |
APC anti-human CD38 | S17015F | FC |
PE/Fire™ 640 anti-human CD38 | S17015F | FC |
Spark YG™ 581 anti-human CD38 | S17015F | FC |
PE/Dazzle™ 594 anti-human CD38 Antibody | S17015F | FC |
KIRAVIA Blue 520™ anti-human CD38 | S17015F | FC |
PE/Fire™ 810 anti-human CD38 Antibody | S17015F | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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PE anti-human CD38
Human peripheral blood lymphocytes were stained with CD38 (c... -
FITC anti-human CD38
Human peripheral blood lymphocytes were stained with anti-hu... -
APC/Fire™ 750 anti-human CD38
Human peripheral lymphocytes were stained with CD38 (clone S... -
Purified anti-human CD38
Human peripheral blood lymphocytes were stained with purifie... -
Alexa Fluor® 700 anti-human CD38
Human peripheral blood lymphocytes were stained with anti-hu... -
PerCP/Cyanine5.5 anti-human CD38
Human peripheral blood lymphocytes were stained with anti-hu... -
PE/Cyanine7 anti-human CD38
Human peripheral lymphocytes were stained with CD38 (clone S... -
APC anti-human CD38
Human peripheral lymphocytes were stained with CD38 (clone S... -
PE/Fire™ 640 anti-human CD38
Human peripheral blood lymphocytes were stained with CD38 (c... -
Spark YG™ 581 anti-human CD38
Human peripheral blood lymphocytes were stained with anti-hu... -
PE/Dazzle™ 594 anti-human CD38 Antibody
Human peripheral blood lymphocytes were stained with anti-hu... -
KIRAVIA Blue 520™ anti-human CD38
Human peripheral lymphocytes were stained with anti-human CD... -
PE/Fire™ 810 anti-human CD38 Antibody
Human peripheral lymphocytes were stained with CD38 (clone S...
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