- Clone
- TX56 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- PVR (poliovirus receptor) homolog
- Isotype
- Rat IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
![TX56_BV510_CD155_Antibody_092717 TX56_BV510_CD155_Antibody_092717](https://d1spbj2x7qk4bg.cloudfront.net/Admin/Public/GetImage.ashx?Image=/Files/Images/media_assets/products/product_images/TX56_BV510_CD155_Antibody_092717.png&Width=240&Height=300&altFmImage_path=&Compression=90&Crop=5)
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C57CL/6 thymocytes were stained with anti-mouse CD4 (clone GK1.5) PE, anti-mouse CD8a (clone 53-6.7) APC, and either anti-mouse CD155 (clone TX56) Brilliant Violet 510™ (filled histogram) or rat IgG2a, κ (clone RTK2758) Brilliant Violet 510™ (dashed histogram). Histograms shown are derived from the following populations: CD4-8+ (top left), CD4+CD8+ (top right), CD4+CD8- (bottom right), CD4-CD8- (bottom left).
Mouse CD155, also known as homolog of polivirus receptor (PVR), is the founding member of a subfamily of immunoglobulin-like adhesion receptors (nectins). Mouse CD155 is expressed on a wide variety of cells of hematopoietic origin apart from its existence on the epithelial cells. The engagement of CD155 with CD226 and CD96 induces cytotoxicity of NK cells and CTL.
Product DetailsProduct Details
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- CD155 transfectants
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA).
- Preparation
- The antibody was purified by affinity chromatography and conjugated with Brilliant Violet 510™ under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Brilliant Violet 510™ excites at 405 nm and emits at 510 nm. The bandpass filter 510/50 nm is recommended for detection, although filter optimization may be required depending on other fluorophores used. Be sure to verify that your cytometer configuration and software setup are appropriate for detecting this channel. Refer to your instrument manual or manufacturer for support. Brilliant Violet 510™ is a trademark of Sirigen Group Ltd.
Learn more about Brilliant Violet™.
This product is subject to proprietary rights of Sirigen Inc. and is made and sold under license from Sirigen Inc. The purchase of this product conveys to the buyer a non-transferable right to use the purchased product for research purposes only. This product may not be resold or incorporated in any manner into another product for resale. Any use for therapeutics or diagnostics is strictly prohibited. This product is covered by U.S. Patent(s), pending patent applications and foreign equivalents. - Excitation Laser
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Violet Laser (405 nm)
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Application References
(PubMed link indicates BioLegend citation) -
- Tahara-Hanaoka S, et al. 2004. Int. Immunol. 16:533.
- Maier MK, et al. 2007. Eur. J. Immunol.. 37:2214.
- Bottino C, et al. 2003. J. Exp. Med. 198:557.
- Dressel R, et al. 2010. FASEB J. 9:134. PubMed
- RRID
-
AB_2716239 (BioLegend Cat. No. 131527)
Antigen Details
- Structure
- 70 kd immunoglobulin-like molecule with three Ig-like domains.
- Distribution
-
CD155 is expressed at cell junctions on the primary vascular endothelial cells. Moreover, mouse CD155 is highly expressed on DP thymocytes and expression level is dropped in peripheral single positive CD4+ and CD8+ T cells. CD155 can be detected on T reg, other activated T cells and on NKT cells. Resident monocytes express moderate amount of CD155, but upregulated its expression during inflammation. Other cells, such as IEL, neutrophils and subsets of B cells were found to express CD155 to varying extents.
- Function
- Apart from its function of adhering junction among contacting epithelial cells, the interaction of DNAM-1 (CD226) with its ligands CD155 and CD112 (nectin 2) induces cytotoxcity of NK cells and CD8+ T cells and cytokine secretion.
- Ligand/Receptor
- CD226 (DNAM-1), CD96
- Cell Type
- B cells, Endothelial cells, Neutrophils, Thymocytes, Tregs
- Biology Area
- Immunology
- Molecular Family
- Adhesion Molecules, CD Molecules, Immune Checkpoint Receptors
- Antigen References
-
1. Mendelsohn C, et al. 1989. Cell 56:855.
- Gene ID
- 52118 View all products for this Gene ID
- UniProt
- View information about CD155 on UniProt.org
Related Pages & Pathways
Pages
Related FAQs
Other Formats
View All CD155 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Biotin anti-mouse CD155 (PVR) | TX56 | FC |
PE anti-mouse CD155 (PVR) | TX56 | FC |
Purified anti-mouse CD155 (PVR) | TX56 | FC |
APC anti-mouse CD155 (PVR) | TX56 | FC |
PE/Cyanine7 anti-mouse CD155 (PVR) | TX56 | FC |
PerCP/Cyanine5.5 anti-mouse CD155 (PVR) | TX56 | FC |
PE/Dazzle™ 594 anti-mouse CD155 (PVR) | TX56 | FC |
Brilliant Violet 711™ anti-mouse CD155 (PVR) | TX56 | FC |
Brilliant Violet 605™ anti-mouse CD155 (PVR) | TX56 | FC |
Brilliant Violet 421™ anti-mouse CD155 (PVR) | TX56 | FC |
Brilliant Violet 650™ anti-mouse CD155 (PVR) | TX56 | FC |
Brilliant Violet 510™ anti-mouse CD155 (PVR) | TX56 | FC |
Brilliant Violet 785™ anti-mouse CD155 (PVR) | TX56 | FC |
Alexa Fluor® 647 anti-mouse CD155 (PVR) | TX56 | FC |
TotalSeq™-A1011 anti-mouse CD155 (PVR) | TX56 | PG |
TotalSeq™-C1011 anti-mouse CD155 (PVR) | TX56 | PG |
TotalSeq™-B1011 anti-mouse CD155 (PVR) | TX56 | PG |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Biotin anti-mouse CD155 (PVR)
C57BL/6 mouse thymocytes were stained with biotinylated CD15... -
PE anti-mouse CD155 (PVR)
C57BL/6 thymocytes stained with TX56 PE -
Purified anti-mouse CD155 (PVR)
-
APC anti-mouse CD155 (PVR)
C57BL/6 splenocytes stained with TX56 APC C57BL/6 thymocytes stained with TX56 APC -
PE/Cyanine7 anti-mouse CD155 (PVR)
C57BL/6 thymocytes were stained with CD155 (clone TX56) PE/C... -
PerCP/Cyanine5.5 anti-mouse CD155 (PVR)
C57BL/6 thymocytes were stained with CD155 (clone TX56) PerC... -
PE/Dazzle™ 594 anti-mouse CD155 (PVR)
C57BL/6 mouse thymocytes were stained with CD155 (clone TX56... -
Brilliant Violet 711™ anti-mouse CD155 (PVR)
C57BL/6 thymocytes were stained with anti-mouse CD4 (clone G... -
Brilliant Violet 605™ anti-mouse CD155 (PVR)
C57BL/6 thymocytes were stained with anti-mouse CD4 (clone G... -
Brilliant Violet 421™ anti-mouse CD155 (PVR)
C57BL/6 thymocytes were stained with anti-mouse CD4 (clone G... -
Brilliant Violet 650™ anti-mouse CD155 (PVR)
C57BL/6 thymocytes were stained with anti-mouse CD4 (clone G... -
Brilliant Violet 510™ anti-mouse CD155 (PVR)
C57CL/6 thymocytes were stained with anti-mouse CD4 (clone G... -
Brilliant Violet 785™ anti-mouse CD155 (PVR)
C57CL/6 thymocytes were stained with anti-mouse CD4 (clone G... -
Alexa Fluor® 647 anti-mouse CD155 (PVR)
C57CL/6 thymocytes were stained with anti-mouse CD4 (clone G... -
TotalSeq™-A1011 anti-mouse CD155 (PVR)
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TotalSeq™-C1011 anti-mouse CD155 (PVR)
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TotalSeq™-B1011 anti-mouse CD155 (PVR)
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