- Clone
- S18001A (See other available formats)
- Regulatory Status
- RUO
- Other Names
- CXCR3, G protein-coupled receptor 9 (GPR9), CKR-L2, IP10 receptor (IP10-R), Mig receptor (Mig-R)
- Isotype
- Rat IgG2b, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
![S18001A_BV510_CD183_Antibody_Updated_040821.png S18001A_BV510_CD183_Antibody_Updated_040821.png](https://d1spbj2x7qk4bg.cloudfront.net/Admin/Public/GetImage.ashx?Image=/Files/Images/media_assets/products/product_images/S18001A_BV510_CD183_Antibody_Updated_040821.png&Width=240&Height=300&altFmImage_path=&Compression=90&Crop=5)
-
C57BL/6 splenocytes were stained with anti-mouse CD3ε APC/Cyanine7 and anti-mouse CD183 (CXCR3) (clone S18001A) Brilliant Violet 510™ (left) or rat IgG2b, κ Brilliant Violet 510™ isotype control (right).
CD183, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes, or granulocytes.
Product DetailsProduct Details
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Mouse CXCR3-transfectants
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with Brilliant Violet 510™ under optimal conditions.
- Concentration
- 0.2 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
Brilliant Violet 510™ excites at 405 nm and emits at 510 nm. The bandpass filter 510/50 nm is recommended for detection, although filter optimization may be required depending on other fluorophores used. Be sure to verify that your cytometer configuration and software setup are appropriate for detecting this channel. Refer to your instrument manual or manufacturer for support. Brilliant Violet 510™ is a trademark of Sirigen Group Ltd.
Learn more about Brilliant Violet™.
This product is subject to proprietary rights of Sirigen Inc. and is made and sold under license from Sirigen Inc. The purchase of this product conveys to the buyer a non-transferable right to use the purchased product for research purposes only. This product may not be resold or incorporated in any manner into another product for resale. Any use for therapeutics or diagnostics is strictly prohibited. This product is covered by U.S. Patent(s), pending patent applications and foreign equivalents. - Excitation Laser
-
Violet Laser (405 nm)
- RRID
-
AB_2892319 (BioLegend Cat. No. 155919)
Antigen Details
- Structure
- 38 kD seven pass transmembrane receptor coupled to G-protein.
- Distribution
-
T cells, plasmacytoid dendritic cells, GM-CSF activated CD34+ hematopoietic progenitors
- Function
- Essential in T cell recruitment to sites of inflammation
- Ligand/Receptor
- CXCL10, CXCL9, CXCL11 and CXCL4
- Cell Type
- Dendritic cells, Hematopoietic stem and progenitors, T cells
- Biology Area
- Immunology
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors, GPCR
- Antigen References
-
- Farber JM. 1997. J. Leukoc. Biol. 61(3):\246-57.
- Bonecchi R, et al. 1998. J. Exp. Med. 187(1):129-34.
- Aota K, et al. 2018. J. Oral. Pathol. Med. 12756.
- Kim B, et al. 2018. Data. Brief. 18:518-522.
- Saahene RO, et al. 2018. Cancer Biother. Radiopharm. 2450.
- Gene ID
- 12766 View all products for this Gene ID
- UniProt
- View information about CD183 on UniProt.org
Related Pages & Pathways
Pages
Other Formats
View All CD183 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-mouse CD183 (CXCR3) | S18001A | FC |
PE anti-mouse CD183 (CXCR3) | S18001A | FC |
APC anti-mouse CD183 (CXCR3) | S18001A | FC |
Brilliant Violet 421™ anti-mouse CD183 (CXCR3) | S18001A | FC |
PE/Cyanine7 anti-mouse CD183 (CXCR3) | S18001A | FC |
PE/Dazzle™ 594 anti-mouse CD183 (CXCR3) | S18001A | FC |
PerCP/Cyanine5.5 anti-mouse CD183 (CXCR3) | S18001A | FC |
Brilliant Violet 605™ anti-mouse CD183 (CXCR3) Antibody | S18001A | FC |
Brilliant Violet 711™ anti-mouse CD183 (CXCR3) Antibody | S18001A | FC |
Brilliant Violet 510™ anti-mouse CD183 (CXCR3) Antibody | S18001A | FC |
PE/Fire™ 640 anti-mouse CD183 (CXCR3) | S18001A | FC |
PE/Fire™ 810 anti-mouse CD183 (CXCR3) | S18001A | FC |
PerCP/Fire™ 780 anti-mouse CD183 (CXCR3) | S18001A | FC |
PE/Cyanine5 anti-mouse CD183 (CXCR3) | S18001A | FC |
PE/Fire™ 700 anti-mouse CD183 (CXCR3) | S18001A | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
-
Purified anti-mouse CD183 (CXCR3)
C57BL/6 splenocytes stained with CD45R/B220 FITC and purifie... -
PE anti-mouse CD183 (CXCR3)
C57BL/6 splenocytes stained with CD45R/B220 APC and CD183 (C... -
APC anti-mouse CD183 (CXCR3)
C57BL/6 splenocytes were stained with CD45R/B220 APC/Cyanine... -
Brilliant Violet 421™ anti-mouse CD183 (CXCR3)
C57BL/6 splenocytes stained with CD3ε APC/Cyanine 7 and CD18... -
PE/Cyanine7 anti-mouse CD183 (CXCR3)
C57BL/6 splenocytes stained with CD3ε FITC and CD183 (CXCR3)... -
PE/Dazzle™ 594 anti-mouse CD183 (CXCR3)
C57BL/6 splenocytes were stained with CD3ε FITC and CD183 (C... -
PerCP/Cyanine5.5 anti-mouse CD183 (CXCR3)
C57BL/6 splenocytes stained with CD3ε FITC and CD183 (CXCR3)... -
Brilliant Violet 605™ anti-mouse CD183 (CXCR3) Antibody
C57BL/6 splenocytes were stained with anti-mouse CD3ε FITC a... -
Brilliant Violet 711™ anti-mouse CD183 (CXCR3) Antibody
C57BL/6 splenocytes were stained with anti-mouse CD3ε FITC a... -
Brilliant Violet 510™ anti-mouse CD183 (CXCR3) Antibody
C57BL/6 splenocytes were stained with anti-mouse CD3ε APC/Cy... -
PE/Fire™ 640 anti-mouse CD183 (CXCR3)
C57BL/6 splenocytes were stained with anti-mouse CD3ε FITC a... -
PE/Fire™ 810 anti-mouse CD183 (CXCR3)
C57BL/6 splenocytes were stained with anti-mouse CD3ε FITC a... -
PerCP/Fire™ 780 anti-mouse CD183 (CXCR3)
C57BL/6 mouse splenocytes were stained with anti-mouse CD3ε... -
PE/Cyanine5 anti-mouse CD183 (CXCR3)
C57BL/6 mouse splenocytes were stained with anti-mouse CD3 F... -
PE/Fire™ 700 anti-mouse CD183 (CXCR3)
C57BL/6 mouse splenocytes were stained with anti-mouse CD3ε ...
Follow Us