- Clone
- RR3-15 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- TCR Vβ-11, V beta 11 TCR, Vβ11 T-cell receptor
- Isotype
- Rat IgG2b, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
![RR3-15_PE_1_060710 RR3-15_PE_1_060710](https://d1spbj2x7qk4bg.cloudfront.net/Admin/Public/GetImage.ashx?Image=/Files/Images/media_assets/products/product_images/RR3-15_PE_1_060710.jpg&Width=240&Height=300&altFmImage_path=&Compression=90&Crop=5)
-
C57BL/6 mouse splenocytes stained with CD3 (145-2C11) APC and RR3-15 PE -
C57BL/6 mouse splenocytes stained with CD3 (145-2C11) APC and rat IgG2b, κ (RTK4530) PE isotype control
Cat # | Size | Price | Save |
---|---|---|---|
139003 | 25 µg | ¥17,450 | |
139004 | 100 µg | ¥38,100 |
T cell receptor (TCR) is a heterodimer consisting of an α and a β chain (TCR α/β) or a γ and a δ chain (TCR γ/δ). TCR-β is a member of the immunoglobulin superfamily and a component of the CD3/TCR complex. The CD3/TCR complex plays a key role in antigen recognition, signal transduction, and T cell activation. V β 11-bearing T cells are largely absent from strains of mice that express MHC class II molecule I-E. It has been demonstrated that the expression of I-E molecule is necessary for the clonal deletion of V beta 11-bearing T cells, but not sufficient for the clonal elimination of V beta 11-bearing T cells.
Product DetailsProduct Details
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Mouse cytolytic T-cell clone OH6
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
-
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
-
Additional reported applications (for relevant formats) include: Western Blot1.
-
Application References
(PubMed link indicates BioLegend citation) -
- Bill J, et al. 1989. J. Exp. Med. 169:1405. (WB)
- Product Citations
-
- RRID
-
AB_10613472 (BioLegend Cat. No. 139003)
AB_10612759 (BioLegend Cat. No. 139004)
Antigen Details
- Structure
- A member of Ig superfamily, heterodimerized with α TCR α chain, and associated with CD3 complex.
- Distribution
-
Subsets of T cells and thymocytes.
- Function
- Antigen recognition.
- Ligand/Receptor
- Antigens
- Cell Type
- T cells, Thymocytes
- Biology Area
- Adaptive Immunity, Immunology
- Molecular Family
- TCRs
- Antigen References
-
1. Davis MM, et al. 1998. Ann. Rev. Immunol. 16:523.
2. Kubo R, et al. 1989. J. Immunol. 142:2736.
3. Haqqi TM, et al. 1989. J. Exp. Med. 169:1903.
4. Behlke MA, et al. 1986. Proc. Natl. Acad. Sci. USA 83:767.
5. Gao EK, et al. 1989. J. Exp. Med. 170:1947. - Gene ID
- 21577 View all products for this Gene ID
- UniProt
- View information about TCR Vbeta11 on UniProt.org
Related Pages & Pathways
Pages
Related FAQs
- What type of PE do you use in your conjugates?
- We use R-PE in our conjugates.
Other Formats
View All TCR Vβ11 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
PE anti-mouse TCR Vβ11 | RR3-15 | FC |
Customers Also Purchased
![](https://d1spbj2x7qk4bg.cloudfront.net/Files//Images/media_assets/products/product_images/MR11-1_PE_071410.jpg)
![](https://d1spbj2x7qk4bg.cloudfront.net/Files//Images/media_assets/products/product_images/RR4-7_PE_060710.jpg)
![](https://d1spbj2x7qk4bg.cloudfront.net/Files//Images/media_assets/products/product_images/MR12-4_PE_060710.jpg)
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
Follow Us