- Clone
- QA18A56 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- C-C motif chemokine receptor 2, CD192
- Isotype
- Rat IgG2b, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
![QA18A56_PECyanine7_CD192_CCR2_Antibody_111220 QA18A56_PECyanine7_CD192_CCR2_Antibody_111220](https://d1spbj2x7qk4bg.cloudfront.net/Admin/Public/GetImage.ashx?Image=/Files/Images/media_assets/products/product_images/QA18A56_PECyanine7_CD192_CCR2_Antibody_111220.png&Width=240&Height=300&altFmImage_path=&Compression=90&Crop=5)
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C57BL/6 bone marrow cells were stained with anti-mouse Ly-6G PerCP/Cyanine5.5, anti-mouse CD11b FITC, and anti-mouse CD192 (CCR2) recombinant (clone QA18A56) PE/Cyanine7 (left) or rat IgG2b, κ PE/Cyanine7 isotype control (right). Dot plots were gated on Ly-6G negative cells.
Cat # | Size | Price | Save |
---|---|---|---|
160107 | 25 µg | ¥37,620 | |
160108 | 100 µg | ¥81,400 |
CD192, also known as CCR2, is a 42 kD G-protein coupled receptor that is associated with bone marrow homeostasis. Specifically, CD192 mediates monocyte chemotaxis and acts as a receptor for monocyte chemoattractant protein 1 (MCP-1). CD192 is primarily expressed on monocytes and macrophages, with some expression on basophils. It is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis and cancer.
Product DetailsProduct Details
- Verified Reactivity
- Mouse
- Antibody Type
- Recombinant
- Host Species
- Rat
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
- Concentration
- 0.2 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
-
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
-
This clone binds to CD192, also known as CCR2, in mouse.
This recombinant antibody clone is derived from clone SA203G11. - RRID
-
AB_2888841 (BioLegend Cat. No. 160107)
AB_2888841 (BioLegend Cat. No. 160108)
Antigen Details
- Structure
- G-protein-coupled receptor, 7-transmembrane protein, 42 kD.
- Distribution
-
Monocytes/macrophages and basophils
- Function
- Mediator of monocyte chemotaxis and bone marrow homeostasis
- Ligand/Receptor
- MCP-1, Ccl2, Ccl7, and Ccl13
- Cell Type
- Basophils, Macrophages, Monocytes
- Biology Area
- Immunology
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors, GPCR
- Antigen References
-
1. Mack M, et al. 2001. J. Immunol. 166:4697.
2. Dutta P, et al. 2015. Cell Stem Cell. 16:477.
3. Li L, et al. 2008. Kidney Int. 74:1526. - Gene ID
- 12772 View all products for this Gene ID
- UniProt
- View information about CD192 on UniProt.org
Related Pages & Pathways
Pages
Other Formats
View All Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-mouse CD192 (CCR2) Recombinant Antibody | QA18A56 | FC |
APC anti-mouse CD192 (CCR2) Recombinant Antibody | QA18A56 | FC |
PE anti-mouse CD192 (CCR2) Recombinant Antibody | QA18A56 | FC |
PE/Cyanine7 anti-mouse CD192 (CCR2) Recombinant Antibody | QA18A56 | FC |
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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Purified anti-mouse CD192 (CCR2) Recombinant Antibody
C57BL/6 bone marrow was stained with Ly-6G PE/Cyanine7, CD11... -
APC anti-mouse CD192 (CCR2) Recombinant Antibody
C57BL/6 bone marrow cells were stained with anti-mouse Ly-6G... -
PE anti-mouse CD192 (CCR2) Recombinant Antibody
C57BL/6 bone marrow cells were stained with anti-mouse Ly-6G... -
PE/Cyanine7 anti-mouse CD192 (CCR2) Recombinant Antibody
C57BL/6 bone marrow cells were stained with anti-mouse Ly-6G...
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