- Clone
- N95/35 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- GABA(A)R, α1, Gamma-aminobutyric acid receptor subunit alpha-1, GABA(A) receptor, alpha 1, GABA(A) receptor subunit alpha-1
- Previously
-
Covance Catalog# MMS-5132
- Isotype
- Mouse IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
![N95slash35_Purified_GABRA1_Antibody_WB_010919_updated.png N95slash35_Purified_GABRA1_Antibody_WB_010919_updated.png](https://d1spbj2x7qk4bg.cloudfront.net/Admin/Public/GetImage.ashx?Image=/Files/Images/media_assets/products/product_images/N95slash35_Purified_GABRA1_Antibody_WB_010919_updated.png&Width=240&Height=300&altFmImage_path=&Compression=90&Crop=5)
-
Western blot of purified anti-GABRA1 antibody (clone N95/35). Lane 1: Molecular weight marker; Lane 2: 20 µg of human brain nuclear lysate; Lane 3: 20 µg of mouse brain nuclear lysate; Lane 4: 20 µg of rat brain nuclear lysate. The blot was incubated with 0.1 µg/mL of the primary antibody overnight at 4°C, followed by incubation with HRP labeled goat anti-mouse IgG (Cat. No. 405306). Enhanced chemiluminescence was used as the detection system.
Gamma-aminobutyric acid receptor subunit alpha-1 (GABRA1) is a component of the hetero-pentameric receptor for gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the vertebrate brain. The receptor is a ligand-gated multi-subunit chloride channel. Mutations in the GABRA1 gene have been associated with juvenile myoclonic epilepsy and childhood absence epilepsy type 4.
Product DetailsProduct Details
- Verified Reactivity
- Human, Mouse, Rat
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- This monoclonal antibody was raised against a fusion protein corresponding to amino acids 355-394 (cytoplasmic loop) of human GABA(A)R, Alpha1.
- Formulation
- Phosphate-buffered solution.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 1 mg/ml
- Storage & Handling
- This antibody should be handled aseptically as it is free of preservatives such as Sodium Azide. Store this antibody undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check the vial label or CoA to find the proper storage conditions.
- Application
-
WB - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.1 - 10 µg per ml. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
-
AB_2564955 (BioLegend Cat. No. 832301)
Antigen Details
- Structure
- Expected MW: 52 kD
- Cell Type
- GABAergic Neurons
- Biology Area
- Cell Biology, Neuroscience, Neuroscience Cell Markers, Synaptic Biology
- Molecular Family
- Postsynaptic proteins
- Gene ID
- 2554 View all products for this Gene ID
- UniProt
- View information about GABRA1 on UniProt.org
Related Pages & Pathways
Pages
Related FAQs
Other Formats
View All GABRA1 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-GABRA1 | N95/35 | WB |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
-
Purified anti-GABRA1
Western blot of purified anti-GABRA1 antibody (clone N95/35)...
Follow Us