Purified anti-human myeloid antigen Antibody

Pricing & Availability
Clone
BM-1 (See other available formats)
Regulatory Status
RUO
Other Names
myeloid specific antigen, p183 DNA-binding cytoplasmic protein
Isotype
Mouse IgG1, κ
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Product Citations
publications
BM-1_Pure_021508
Human myeloid cell line HL60 intracellular stained with purified BM-1, followed by anti-mouse IgG FITC
  • BM-1_Pure_021508
    Human myeloid cell line HL60 intracellular stained with purified BM-1, followed by anti-mouse IgG FITC
Cat # Size Price Save
327102 100 µg ¥25,960
Description

BM-1 antigen is a 183 kD myeloid-specific-DNA-binding protein which is expressed in myeloid cells, including myeloid precursors and mature granulocytes. It is also expressed in chronic myeloid leukemia (CML) and M2 and M3 acute myeloid leukemias (AML) as well as myelomonocytic leukemias, but not in T, B, NK and other non-hematopoietic cells. The biological function of this antigen is not clear, although it has been proposed that BM-1 may play a role in the differentiation of myeloid cells.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
PWM-stimulated human PBL
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

ICFC - Quality tested
IHC-P, IHC-F, IP - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Additional reported (for the relevant formats) applications include: immunohistochemical staining of frozen and paraffin sections1, and immunoprecipitation1.

Application References

(PubMed link indicates BioLegend citation)
  1. Epstein AL, et al.1987. Blood 70:1124.
RRID
AB_893592 (BioLegend Cat. No. 327102)

Antigen Details

Structure
183 kD, DNA-binding protein
Distribution

In myeloid cells

Antigen References

1. Epstein AL, et al. 1987. Blood 70:1124.

Gene ID
861 View all products for this Gene ID
UniProt
View information about myeloid antigen on UniProt.org
Go To Top Version: 1    Revision Date: 04/02/2014

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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