- Clone
- SA17RN1 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Tetraspanin-33, BAAM, Penumbra, PEN
- Isotype
- Mouse IgG2b, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
![/SA17RN1_Purified_TSPAN33_Antibody_122718.png /SA17RN1_Purified_TSPAN33_Antibody_122718.png](https://d1spbj2x7qk4bg.cloudfront.net/Admin/Public/GetImage.ashx?Image=/Files/Images/media_assets/products/product_images/SA17RN1_Purified_TSPAN33_Antibody_122718.png&Width=240&Height=300&altFmImage_path=&Compression=90&Crop=5)
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Human peripheral blood lymphocytes resting (right) or stimulated overnight with recombinant human CD40L (TNFSF5) plus IL-4 (left), were stained with purified TSPAN33 (clone SA17RN1) followed by anti-mouse IgG PE and CD19 APC.
TSPAN33, also known as BAAM, is a 32 kDa protein member of the TM4 superfamily (TM4SF). TSPAN33 have four transmembrane regions and two extracellular loops, one of them is a cysteine-rich long extracellular loop (LEL), characteristic of the TM4SF. TSPAN33 interacts with different molecules such as integrins and other tetraspanins. TSPAN33 is expressed by activated B cells, some B cell lymphomas, macrophages and in cells from the convoluted tubules and collecting ducts in the kidney. In macrophages TSPAN33 modulates TLR-induced proinflammatory gene expression, but its function in other cells is unknown.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human TSPAN33-transfected cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
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FC - Quality tested
- Recommended Usage
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Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Product Citations
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- RRID
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AB_2783314 (BioLegend Cat. No. 395402)
Antigen Details
- Structure
- Member of the TM4 superfamily, TspanC8 subgroup, 32kD, 4 transmembrane regions, 1 cysteine-rich long extracellular loop (LEL).
- Distribution
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Activated B cells, some B cell lymphomas, macrophages, convoluted tubules and collecting ducts from kidney
- Function
- Modulates TLR-induced proinflammatory gene expression
- Cell Type
- B cells, Macrophages
- Biology Area
- Cancer Biomarkers, Immuno-Oncology, Signal Transduction
- Molecular Family
- Adhesion Molecules
- Antigen References
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- Pérez-Martínez CA, et al. 2017. Scand J Immunol. 86:23.
- Ruiz-García A, et al. 2016. J Immunol. 197:3371.
- Luu VP, et al. 2013. Clin Immunol. 149:388.
- Chen Z, et al. 2005. Cancer Genet Cytogenet. 162:95.
- Maecker HT et al. 1997. FASEB J. 11:428.
- Gene ID
- 340348 View all products for this Gene ID
- UniProt
- View information about TSPAN33 on UniProt.org
Other Formats
View All TSPAN33 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-human TSPAN33 (BAAM) | SA17RN1 | FC |
PE anti-human TSPAN33 (BAAM) | SA17RN1 | FC |
APC anti-human TSPAN33 (BAAM) | SA17RN1 | FC |
Biotin anti-human TSPAN33 (BAAM) | SA17RN1 | FC |
Brilliant Violet 421™ anti-human TSPAN33 (BAAM) | SA17RN1 | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human TSPAN33 (BAAM)
Human peripheral blood lymphocytes resting (right) or stimul... -
PE anti-human TSPAN33 (BAAM)
Human peripheral blood lymphocytes resting (right) or stimul... -
APC anti-human TSPAN33 (BAAM)
Human peripheral blood lymphocytes were stimulated overnight... -
Biotin anti-human TSPAN33 (BAAM)
Human peripheral blood lymphocytes stimulated overnight with... -
Brilliant Violet 421™ anti-human TSPAN33 (BAAM)
Human peripheral blood lymphocytes were stimulated overnight...
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