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- Clone
- BB7.1 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- HLA-A7, HLA-B*07, HLA Class I histocompatibility antigen B alpha chain
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
Human peripheral blood lymphocytes were stained with PE HLA-B7 (clone BB7.1, filled histogram) or PE mouse IgG1, κ isotype control (open histogram).
| Cat # | Size | Price | Save |
|---|---|---|---|
| 372403 | 25 tests | ¥26,840 | |
| 372404 | 100 tests | ¥69,740 |
HLA-B belongs to the HLA class I heavy chain paralogues. HLA-B7 is a serotype of HLA-B and one of the common HLA types. MHC class I heavy chains associate with β2-microglobulin and are expressed on nearly all nucleated cells. MHC class I molecules are involved in the presentation of of antigens to CD8+ T cells and thereby play an important role in cell-mediated immune responses and immune surveillance.
Product DetailsProduct Details
- Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Papain solubilized HLA antigen, B7.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
- Excitation Laser
-
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
-
Application References
(PubMed link indicates BioLegend citation) -
- Dellgren C, et al. 2015. PLoS One 10:e0135385.
- Brodsky F, et al. 1979. Immunol. Rev. 47:3.
- Rancan C, et al. 2015. PLoS Pathog. 11:e1004906.
- Levering W, et al. 2000. Cytometry 42:95.
- Product Citations
- RRID
-
AB_2650773 (BioLegend Cat. No. 372403)
AB_2650774 (BioLegend Cat. No. 372404)
Antigen Details
- Structure
- Ig superfamily.
- Distribution
-
Nearly all cells from HLA-B*07 individuals.
- Function
- Antigen peptide presentation.
- Ligand/Receptor
- TCR, CD8.
- Biology Area
- Immunology
- Molecular Family
- MHC Antigens
- Gene ID
- 3106 View all products for this Gene ID
- UniProt
- View information about HLA-B7 on UniProt.org
Related FAQs
- What type of PE do you use in your conjugates?
- We use R-PE in our conjugates.
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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