- Clone
- S17007L (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Siglec-5
- Isotype
- Rat IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
![S17007L_BV711_CD170_Antibody_1_021424 S17007L_BV711_CD170_Antibody_1_021424](https://d1spbj2x7qk4bg.cloudfront.net/Admin/Public/GetImage.ashx?Image=/Files/Images/media_assets/products/product_images/S17007L_BV711_CD170_Antibody_1_021424.png&Width=240&Height=300&altFmImage_path=&Compression=90&Crop=5)
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C57BL/6 mouse splenocytes were stained with anti-mouse CD193 (clone J073E5) FITC and anti-mouse CD170 (Siglec-F) (clone S17007L) Brilliant Violet™ 711 (left) or rat IgG2a, κ Brilliant Violet™ 711 isotype control (right).
Cat # | Size | Price | Quantity Check Availability | Save | ||
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155537 | 50 µg | 172€ |
CD170, also known as Siglec-F, Siglec-5, is a member of the Sialic acid-binding Ig-like lectin family, type I single pass transmembrane protein, with 4 extracellular Ig-like domains and 2 ITIM motifs in the cytoplasmic domain; preferentially binds [alpha]-2,3-linked sialic acid. Siglec F is expressed in eosinophils, alveolar macrophages and intestinal microfold (M) cells and induces apoptosis of the lung eosinophis during allergic asthma.
Product DetailsProduct Details
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with Brilliant Violet 711™ under optimal conditions.
- Concentration
- 0.2 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
Brilliant Violet 711™ excites at 405 nm and emits at 711 nm. The bandpass filter 710/50 nm is recommended for detection, although filter optimization may be required depending on other fluorophores used. Be sure to verify that your cytometer configuration and software setup are appropriate for detecting this channel. Refer to your instrument manual or manufacturer for support. Brilliant Violet 711™ is a trademark of Sirigen Group Ltd.
Learn more about Brilliant Violet™.
This product is subject to proprietary rights of Sirigen Inc. and is made and sold under license from Sirigen Inc. The purchase of this product conveys to the buyer a non-transferable right to use the purchased product for research purposes only. This product may not be resold or incorporated in any manner into another product for resale. Any use for therapeutics or diagnostics is strictly prohibited. This product is covered by U.S. Patent(s), pending patent applications and foreign equivalents. - Excitation Laser
-
Violet Laser (405 nm)
- RRID
-
AB_3097569 (BioLegend Cat. No. 155537)
Antigen Details
- Structure
- Member of the Sialic acid-binding Ig-like lectin family, type I, single pass, transmembrane protein, 4 extracellular Ig-like domains, 2 ITIM motifs in the cytoplasmic domain
- Distribution
-
Eosinophils, alveolar macrophages, intestinal microfold (M) cells
- Function
- Induces apoptosis in eosinophils
- Ligand/Receptor
- [alpha]-2,3-linked sialic acid
- Cell Type
- Eosinophils, Macrophages
- Biology Area
- Apoptosis/Tumor Suppressors/Cell Death, Cell Biology, Immunology, Innate Immunity
- Molecular Family
- CD Molecules, Siglec Molecules
- Antigen References
-
- Gicheva N, et al. 2016. Biochem. Biophys. Res. Commun. 479:1.
- Kiwamoto T, et al. 2015. J. Allergy Clin. Immunol. 135:1329.
- Suzukawa M, et al. 2013. J. Immunol. 190:5939.
- Patnode ML, et al. 2013. J. Biol. Chem. 288:26533.
- Gene ID
- 233186 View all products for this Gene ID
- UniProt
- View information about CD170 on UniProt.org
Related Pages & Pathways
Pages
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-mouse CD170 (Siglec-F)
C57BL/6 mouse splenocytes were stained with CD170 (Siglec-F)... -
FITC anti-mouse CD170 (Siglec-F)
C57BL/6 mouse splenocytes were stained with CD193 (CCR3, clo... -
PE anti-mouse CD170 (Siglec-F)
C57BL/6 mouse splenocytes were stained with CD193 (CCR3, clo... -
APC anti-mouse CD170 (Siglec-F)
C57BL/6 mouse splenocytes were stained with CD193 (CCR3, clo... -
Brilliant Violet 421™ anti-mouse CD170 (Siglec-F)
C57BL/6 mouse splenocytes were stained with CD193 (CCR3, clo... -
Biotin anti-mouse CD170 (Siglec-F)
C57BL/6 mouse splenocytes were stained with CD193 (CCR3, clo... -
TotalSeq™-A0431 anti-mouse CD170 (Siglec-F)
-
TotalSeq™-C0431 anti-mouse CD170 (Siglec-F)
-
TotalSeq™-B0431 anti-mouse CD170 (Siglec-F)
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Alexa Fluor® 647 anti-mouse CD170 (Siglec-F) Antibody
C57BL/6 mouse splenocytes were stained with anti-mouse CD193... -
KIRAVIA Blue 520™ anti-mouse CD170 (Siglec-F) Antibody
C57BL/6 mouse splenocytes were stained with anti-mouse CD193... -
Alexa Fluor® 488 anti-mouse CD170 (Siglec-F) Antibody
C57BL/6 mouse splenocytes were stained with anti-mouse CD193... -
PerCP/Cyanine5.5 anti-mouse CD170 (Siglec-F) Antibody
C57BL/6 mouse splenocytes were stained with anti-mouse CD193... -
PE/Cyanine7 anti-mouse CD170 (Siglec-F) Antibody
C57BL/6 mouse splenocytes were stained with anti-mouse CD193... -
PE/Dazzle™ 594 anti-mouse CD170 (Siglec-F) Antibody
C57BL/6 mouse splenocytes were stained with anti-mouse CD193... -
APC/Cyanine7 anti-mouse CD170 (Siglec-F)
C57BL/6 mouse splenocytes were stained with anti-mouse CD193... -
Alexa Fluor® 700 anti-mouse CD170 (Siglec-F)
C57BL/6 mouse splenocytes were stained with anti-mouse CD193... -
PerCP/Fire™ 806 anti-mouse CD170 (Siglec-F)
C57BL/6 mouse splenocytes were stained with anti-mouse CD193... -
Brilliant Violet 711™ anti-mouse CD170 (Siglec-F)
C57BL/6 mouse splenocytes were stained with anti-mouse CD193... -
APC/Fire™ 750 anti-mouse CD170 (Siglec-F)
C57BL/6 mouse splenocytes were stained with anti-mouse CD19... -
APC/Fire™ 810 anti-mouse CD170 (Siglec-F)
C57BL/6 mouse splenocytes were stained with anti-mouse CD193...
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