Purified anti-human MS4A4A Antibody

Pricing & Availability
Clone
5C12/MS4A4A (See other available formats)
Regulatory Status
RUO
Other Names
MS4A4, MS4A7, 4SPAN1, CD20L1, HDCME31P
Isotype
Mouse IgG1, λ
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Product Citations
publications
5C12slashMS4A4A_PURE_MS4A4A_Antibody_1_101316
Human peripheral blood leukocytes were stained with purified anti-human MS4A4A (clone 5C12/MS4A4A) (top) or purified mouse IgG1 isotype control (bottom), followed by PE goat anti-mouse IgG. Cells were then stained with CD14 APC. Data shown was gated on monocyte population.
  • 5C12slashMS4A4A_PURE_MS4A4A_Antibody_1_101316
    Human peripheral blood leukocytes were stained with purified anti-human MS4A4A (clone 5C12/MS4A4A) (top) or purified mouse IgG1 isotype control (bottom), followed by PE goat anti-mouse IgG. Cells were then stained with CD14 APC. Data shown was gated on monocyte population.
  • 5C12slashMS4A4A_PURE_MS4A4A_Antibody_2_101316
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372502 100 µg 240€
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Description

MS4A4A is the "member 4A" of a newly recognized "membrane-spanning 4A (MS4A)" gene family. Each protein of this family has four conservative transmembrane domains, and hence is predicted to traverse the plasma membrane four times. MS4A4A is also known as MS4A4, MS4A7, 4SPAN1, CD20L1, or HDCME31P. MS4A4A may function in signal transduction, although the mechanisms of which are largely unknown.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Human MS4A4A-GFP Transfected 300.19 Mouse Pre-B Cell Line
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2632690 (BioLegend Cat. No. 372502)

Antigen Details

Structure
23 kD, four conservative transmembrane domains.
Distribution

Monocytes, macrophages and mast cells.

Function
Cell signaling.
Interaction
Stem Cell Factor Receptor (KIT)
Cell Type
Monocytes, Macrophages, Mast cells
Biology Area
Cell Biology, Immunology, Signal Transduction
Molecular Family
CD Molecules
Antigen References

1. Ishibashi K, et al. 2001. Gene. 264:87.
2. Cruse G, et al. 2015. Mol. Biol. Cell. 26:1711.

Gene ID
51338 View all products for this Gene ID
UniProt
View information about MS4A4A on UniProt.org
Go To Top Version: 1    Revision Date: 10-13-2016

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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