- Clone
- QA19A42 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Immunoglobulin G
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
![QA19A42_APC_IgG_Antibody_RECOM_091420 QA19A42_APC_IgG_Antibody_RECOM_091420](https://d1spbj2x7qk4bg.cloudfront.net/Admin/Public/GetImage.ashx?Image=/Files/Images/media_assets/products/product_images/QA19A42_APC_IgG_Antibody_RECOM_091420.png&Width=240&Height=300&altFmImage_path=&Compression=90&Crop=5)
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Human DLL4 transfected CHO cells were incubated with recombinant human Notch 1-IgG Fc fusion protein, then stained with anti-human IgG Fc recombinant (clone QA19A42) APC (filled histogram) or mouse IgG1, κ APC isotype control (open histogram).
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
366905 | 25 tests | 152€ | ||||
366906 | 100 tests | 304€ |
IgG Fc is a homodimer composed of the constant region of the two heavy chains that form the IgG molecule. The Fc fragment mediates opsonization, antibody dependent cellular cytotoxicity (ADCC), and complement activation through binding to Fc receptors such as CD16, CD32, CD64, and the complement factor C1.
Product DetailsProduct Details
- Reactivity
- Human
- Antibody Type
- Recombinant
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
-
Red Laser (633 nm)
- Product Citations
- RRID
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AB_2888847 (BioLegend Cat. No. 366905)
AB_2888847 (BioLegend Cat. No. 366906)
Antigen Details
- Structure
- Homodimer formed by the constant region of the IgG heavy chain
- Ligand/Receptor
- CD16, CD32, CD64
- Cell Type
- B cells, Basophils, Dendritic cells, Macrophages, Mast cells, Neutrophils, NK cells, Platelets
- Biology Area
- Adaptive Immunity, Cell Biology, Immunology, Innate Immunity
- Molecular Family
- Fc Receptors
- Antigen References
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- Paul WE. 2003. Fundamental Immunology. Lippincott Williams & Wilkins. Philadelphia PA.
- Gene ID
- 3500 View all products for this Gene ID
- UniProt
- View information about IgG Fc on UniProt.org
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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