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FITC anti-mouse F4/80 Antibody

Pricing & Availability
Clone
BM8 (See other available formats)
Regulatory Status
RUO
Other Names
EMR1, Ly71
Isotype
Rat IgG2a, κ
Ave. Rating
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Product Citations
publications
BM8_FITC_090707
Thioglycolate-elicited Balb/c mouse peritoneal macrophages stained with BM8 FITC
  • BM8_FITC_090707
    Thioglycolate-elicited Balb/c mouse peritoneal macrophages stained with BM8 FITC
Compare all formats See FITC spectral data
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123107 50 µg 52€
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123108 500 µg 148€
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Description

F4/80, also known as EMR1 or Ly71, is a 160 kD glycoprotein of the epidermal growth factor (EGF)-transmembrane 7 (TM7) family. F4/80 has been widely used as a murine macrophage marker. It is expressed on a majority of tissue macrophages, including macrophages in the lung, gut, peritoneal cavity, thymus, and red pulp of the spleen, Kupffer cells, Langerhans cells, microglia, and certain dendritic cells. It is not expressed on macrophages located in the T cell areas of the spleen, lymph node, or Peyer's patch. The biological ligand of F4/80 has not been identified, but it has been reported that F4/80 is required for the induction of CD8+ T cells-mediated peripheral tolerance.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Murine macrophages
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Application Notes

Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen sections1,2 and formalin-fixed paraffin-embedded sections6,7, Western blotting, and spatial biology (IBEX)12,13.

Application References
  1. Schaller E, et al. 2002. Mol. Cell. Biol. 22:8035. (IHC)
  2. Stevceva L, et al. 2001. BMC Clin Pathol. 1:3. (IHC)
  3. Kobayashi M, et al.2008. J. Leukoc. Biol. 83:1354. PubMed
  4. Poeckel D, et al. 2009. J. Biol Chem. 284:21077. PubMed
  5. Glass AM, et al. 2013. J. Immunol. 190:4830. PubMed
  6. Koehm S, et al. 2007. J. Allergy Clin. Immunol. 120:570. (IHC)
  7. Rankin AL, et al. 2010. J. Immunol. 184:1526. (IHC)
  8. Sasi SP, et al. 2014. J Biol Chem. 289:14178. PubMed
  9. Thakus VS, et al. 2014. Toxicol Lett. 230:322. PubMed
  10. Watson NB, et al. 2015. J Immunol. 194:2796. PubMed
  11. Hirakawa H, et al. 2015. PLoS One. 10:119360. PubMed
  12. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  13. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Cacialli P, et al. 2022. EMBO J. 41:e108536. PubMed
  2. Glorieux C, et al. 2022. J Adv Res. 40:109. PubMed
  3. Hamdi L, et al. 2022. Ann Clin Transl Neurol. 9:1792. PubMed
  4. Veazey JM, et al. 2023. Immunol Cell Biol. 101:130. PubMed
  5. Suzuki Y, et al. 2023. Front Immunol. 14:1089905. PubMed
  6. Schwarz N, et al. 2023. FASEB J. 37:e22846. PubMed
  7. Vanneste D, et al. 2023. Nat Immunol. 24:827. PubMed
  8. Saha S, et al. 2023. Sci Rep. 13:4609. PubMed
  9. Zhang X, et al. 2023. Front Immunol. 14:1116749. PubMed
  10. Cui B, et al. 2023. Int Immunopharmacol. 120:110240. PubMed
  11. Liu J, et al. 2019. Immunity. 50:600. PubMed
  12. Xiong Y, et al. 2020. J Nanobiotechnology. 18:66. PubMed
  13. Wang L, et al. 2008. Cancer Res. 68:5639. PubMed
  14. Jiang Z, et al. 2021. J Clin Invest. 131: . PubMed
  15. Vasanthakumar A, et al. 2020. Nature. 579:581. PubMed
  16. Liang J, et al. 2021. Cancer Manag Res. 13:6977. PubMed
  17. Li F, et al. 2022. Mediators Inflamm. 2022:5782922. PubMed
  18. Wang HH, et al. 2022. J Biomed Sci. 29:36. PubMed
  19. Denny L, et al. 2021. Clin Transl Immunology. 10:e1234. PubMed
  20. Li H, et al. 2022. Cancer Cell. 40:36. PubMed
  21. Motyka NI, et al. 2022. Infect Immun. 90:e0063721. PubMed
  22. Tan YY, et al. 2022. Bio Protoc. 12:e4307. PubMed
  23. Yang Y, et al. 2022. FEBS J. 289:5279. PubMed
  24. Corral D, et al. 2022. Cell Rep. 39:110715. PubMed
  25. Wang S, et al. 2022. Sci Adv. 8:eabn3883. PubMed
  26. Doughty D, et al. 2022. Exp Biol Med (Maywood). 247:1433. PubMed
  27. Poh AR, et al. 2022. Sci Adv. 8:eabl7882. PubMed
  28. Piñeros AR, et al. 2022. Cell Rep. 39:111011. PubMed
  29. Li Y, et al. 2023. Bioact Mater. 20:548. PubMed
  30. Poh AR, et al. 2022. Cell Rep. 41:111479. PubMed
  31. Xu S, et al. 2022. EBioMedicine. 86:104312. PubMed
  32. Shang T, et al. 2022. Front Pharmacol. 13:1054176. PubMed
  33. Kraemer AN, et al. 2022. Front Immunol. 13:933191. PubMed
  34. Choi H, et al. 2023. J Nanobiotechnology. 21:5. PubMed
  35. Peng Y, et al. 2023. Respir Res. 24:33. PubMed
  36. Zhong W, et al. 2023. Nat Commun. 14:491. PubMed
  37. Slusarczyk P, et al. 2023. Elife. 12: . PubMed
  38. Sacirbegovic F 2023. Immunity. N/A. PubMed
  39. Li XF, et al. 2023. J Exp Med. 220: . PubMed
  40. Wang L, et al. 2023. Oxid Med Cell Longev. 2023:6480848. PubMed
  41. Wight AE, et al. 2022. Proc Natl Acad Sci U S A. 119:e2200757119. PubMed
  42. Jiang L, et al. 2013. Mol Immunol. 54:14. PubMed
  43. Liu K, et al. 2021. Cell Metabolism. 33(3):666-675.e4. PubMed
  44. Marcil A, et al. 2008. Infect Immun. 76:4345. PubMed
  45. Kimura H, et al. 2017. J Immunol. 10.4049/jimmunol.1601798. PubMed
  46. Zheng M, et al. 2016. Sci Rep. 6:28729. PubMed
  47. Chen Y, et al. 2018. EBioMedicine. 32:31. PubMed
  48. Zhang Y, et al. 2018. Sci Rep. 8:5994. PubMed
  49. Barry KC, et al. 2018. Nat Med. 24:1178. PubMed
  50. Chou YJ, et al. 2020. Sci Rep. 10:8422. PubMed
  51. Hsu SPC, et al. 2020. J Neurooncol. 146:417. PubMed
  52. Morgan PK, et al. 2021. J Biol Chem. 297:101341. PubMed
  53. Hewitson JP, et al. 2020. J Immunol. 204:2949. PubMed
  54. Yang W, et al. 2020. Nat Commun. 3.553472222. PubMed
  55. Mouton AJ, et al. 2018. Basic Res Cardiol. 113:26:00. PubMed
  56. Lee Y, et al. 2017. PLoS One.. 10.1371/journal.pone.0183028. PubMed
  57. Stubelius A, et al. 2017. Immunobiology. 10.1016/j.imbio.2017.05.007. PubMed
  58. Zhang L, et al. 2022. Acta Pharm Sin B. 12:3427. PubMed
  59. Zhou X, et al. 2022. Front Pharmacol. 13:887263. PubMed
  60. Chauhan A, et al. 2020. Nat Commun. 11:1939. PubMed
  61. Rogic A, et al. 2021. Nat Commun. 12:6889. PubMed
  62. Gu T, et al. 2021. Front Immunol. 11:621441. PubMed
  63. Qiu X, et al. 2019. Theranostics. 9:2618. PubMed
  64. Brunner JS, et al. 2020. Nat Commun. 0.757638889. PubMed
  65. Alvarez M, et al. 2020. Cancers (Basel). 12:. PubMed
  66. Shi S, et al. 2020. Clin Cancer Res. 26:5990. PubMed
  67. Wang Y, et al. 2020. J Immunol. 205:2905. PubMed
  68. Zhou HF, et al. 2022. Front Pharmacol. 13:778755. PubMed
  69. Xiong A, et al. 2022. EBioMedicine. 83:104239. PubMed
  70. Royzman D, et al. 2022. Front Immunol. 13:1012647. PubMed
  71. Ohtsuki T, et al. 2016. J Virol. 90: 300 - 307. PubMed
  72. Pan H, et al. 2020. Mol Psychiatry. . PubMed
  73. An YA et al. 2017. eLife. 6 pii: e24071. PubMed
  74. Wang Y, et al. 2022. Front Immunol. 13:767630. PubMed
  75. Kedage V, et al. 2022. MAbs. 14:2040083. PubMed
  76. Xu X, et al. 2021. J Nanobiotechnology. 19:376. PubMed
  77. Ma YV, et al. 2021. MAbs. 13:2003281. PubMed
  78. Dichtl S, et al. 2021. Sci Adv. 7: . PubMed
  79. Klopfenstein N, et al. 2021. PLoS Pathog. 17:e1009387. PubMed
  80. Ostendorf BN, et al. 2020. Nat Med. 26:1048. PubMed
  81. Nakazeki F, et al. 2018. Sci Rep. 8:8553. PubMed
  82. Barger SR, et al. 2019. Nat Commun. 10:1249. PubMed
  83. Zhang S, et al. 2019. Mol Med Rep. 19:5377. PubMed
  84. Dan H, et al. 2020. Mol Oncol. 14:795. PubMed
  85. García-Bonilla M, et al. 2020. Stem Cell Res Ther. 11:121. PubMed
  86. Niss K, et al. 2020. Cell Reports. 31(11):107763. PubMed
  87. Wang F, et al. 2021. Cell Mol Gastroenterol Hepatol. 13:257. PubMed
  88. Xiao P, et al. 2021. JCI Insight. 6:. PubMed
  89. Zheng Y, et al. 2022. Front Pharmacol. 12:816032. PubMed
  90. Jing L, et al. 2022. Front Immunol. 13:864995. PubMed
  91. Zhang X, et al. 2021. Front Immunol. 12:680068. PubMed
  92. Zhang Y, et al. 2022. Nat Commun. 13:4553. PubMed
  93. Geng T, et al. 2022. Methods Mol Biol. 2585:71. PubMed
  94. Xiao Z, et al. 2015. Cancer Lett. 360:302. PubMed
  95. Velázquez K, et al. 2016. Am J Physiol Gastrointest Liver Physiol. 311: G699 - G712. PubMed
  96. Ratitong B, et al. 2021. Cell Reports. 35(7):109139. PubMed
  97. Bignami F, et al. 2017. Acta Ophthalmol. 95:e641. PubMed
  98. Yu H, et al. 2022. J Orthop Surg Res. 17:232. PubMed
  99. Feng T, et al. 2022. Nat Commun. 13:5208. PubMed
  100. Gu Y, et al. 2021. Cell Res. Online ahead of print. PubMed
  101. Kornstädt L, et al. 2021. Front Immunol. 11:607048. PubMed
  102. Zhao X, et al. 2014. J Biol Chem. 289:30052. PubMed
  103. Suo J, et al. 2014. J Leukoc Biol. 96:133. PubMed
  104. Proto JD et al. 2018. Immunity. 49(4):666-677 . PubMed
  105. Wu W, et al. 2018. J Am Soc Nephrol. 29:168. PubMed
  106. Niemann J, et al. 2019. Nat Commun. 10:3236. PubMed
  107. Rashidi M, et al. 2019. J Immunol. 203:736. PubMed
  108. Duan RN, et al. 2021. J Neuroinflammation. 18:145. PubMed
  109. Wang J, et al. 2021. Nat Commun. 12:6198. PubMed
  110. Wang Y, et al. 2021. EMBO J. 40:e105543. PubMed
  111. Odkhuu E, et al. 2014. Innate Immunity. 21:194. PubMed
  112. Lu X, et al. 2016. Nat Commun. 7: 12719. PubMed
  113. Xie Z, et al. 2020. Light Sci Appl. 0.486805556. PubMed
  114. Omori S, et al. 2021. Cell Reports. 34(6):108734. PubMed
  115. DeVito NC, et al. 2021. Cell Reports. 35(5):109071. PubMed
  116. Moon H, et al. 2020. Nat Commun. 4.270138889. PubMed
  117. Wan X, et al. 2018. Nature. 560:107. PubMed
  118. Niknam S, et al. 2018. Clin Cancer Res. 24:5735. PubMed
  119. Tavazoie MF, et al. 2018. Cell. 172:825. PubMed
  120. Yu Y, et al. 2018. Mol Med Rep. 17:8212. PubMed
  121. Irie Y, et al. 2017. J Neuroimmune Pharmacol. 10.1007/s11481-017-9757-2. PubMed
  122. Wang H, et al. 2022. J Nanobiotechnology. 20:445. PubMed
  123. Wang Y, et al. 2022. Cell Death Dis. 13:748. PubMed
  124. Wu Y, et al. 2021. PLoS Negl Trop Dis. 15:e0010050. PubMed
  125. Lewis EL, et al. 2021. Front Immunol. 12:741518. PubMed
  126. Cai C, et al. 2021. Sci Rep. 11:13386. PubMed
  127. Barsoumian HB, et al. 2020. J Immunother Cancer. 8:00. PubMed
  128. Vettorazzi S, et al. 2015. Nat Commun. 6: 7796. PubMed
  129. Miki Y, et al. 2013. J Exp Med. 210:1217. PubMed
  130. Linde N, et al. 2012. PLoS One. 7:e40058. PubMed
  131. Matsumoto K, et al. 2017. PLoS One. 12(6):e0175406. PubMed
  132. Van Winkle JA et al. 2018. Cell host & microbe. 24(5):665-676 . PubMed
  133. Martínez‐López M et al. 2019. Immunity. 50(2):446-461 . PubMed
  134. Liu S, et al. 2020. Cell Host & Microbe. 26(6):779-794.e8.. PubMed
  135. Kasahara D, et al. 2012. J Immunol. 188:4558. PubMed
  136. Zhu Y, et al. 2021. EMBO J. 40:e105320. PubMed
  137. Machácek T, et al. 2022. PLoS Pathog. 18:e1010302. PubMed
  138. Qin W, et al. 2021. FASEB J. 35:e21599. PubMed
  139. Zhang Q, et al. 2022. Nat Commun. 13:2406. PubMed
  140. Artz A, Butz S, Vestweber D 2016. Am J Physiol Renal Physiol. 311: F176 - F181. PubMed
  141. Abe M, et al. 2020. Clin Exp Immunol. 303:199. PubMed
  142. Deng G, et al. 2010. J Immunol. 184:7154. PubMed
  143. Coronel MM, et al. 2020. Sci Adv. 6:eaba5573. PubMed
  144. Stifter SA, et al. 2019. Cell Rep. 29:3539. PubMed
  145. Tomay F, et al. 2019. J Transl Med. 17:237. PubMed
  146. Zheng X, et al. 2018. J Clin Invest. 128:2104. PubMed
  147. Fan Q, et al. 2021. Bioact Mater. 6:4014. PubMed
  148. Koikawa K, et al. 2021. Cell. 184:4753. PubMed
  149. Parayath NN, et al. 2020. Nat Commun. 4.680555556. PubMed
  150. Arce-Cerezo A, et al. 2015. Sci Rep. 5: 1448. PubMed
  151. Torres I, et al. 2014. Infect Immun . 82:4689. PubMed
  152. Taye B, et al. 2017. BMC Genomics . 10.1186/s12864-017-3803-6. PubMed
  153. Wang Y et al. 2017. Cell. 171(2):331-345 . PubMed
  154. Subramanian K, et al. 2019. Nat Microbiol. 4:62. PubMed
  155. Patankar Y, et al. 2015. Am J Physiol Lung Cell Mol Physiol. 309: L902 - L913. PubMed
  156. Uematsu T, et al. 2016. Sci Rep. 6:37815. PubMed
  157. Lu SW, et al. 2020. Nat Commun. 3.660416667. PubMed
  158. Fukushima K, et al. 2020. Immunity. 52(3):542-556. PubMed
  159. Li YT, et al. 2019. Elife. 8:e47642. PubMed
  160. Baomei Wang et al. 2019. Cell reports. 26(6):1614-1626 . PubMed
  161. Du H, et al. 2017. Nat Commun. 10.1038/s41467-017-00522-7. PubMed
  162. Nenasheva T, et al. 2017. PLoS One. 12(6):e0178983. PubMed
  163. Howard ZM, et al. 2022. JCI Insight. 7:. PubMed
  164. Miki Y, et al. 2022. JCI Insight. 7:. PubMed
  165. Anderson-Baucum E, et al. 2021. Cell Metab. 33:1883. PubMed
  166. Raoof R, et al. 2021. J Neurosci. 41:8249. PubMed
  167. Wang X, et al. 2022. J Biol Chem. 298:101561. PubMed
  168. Yuan M, et al. 2022. Oxid Med Cell Longev. 2022:5479491. PubMed
  169. Hou PP, et al. 2020. Molecular Cell. 78(6):1192-1206.e10. PubMed
  170. Sasaki Y, et al. 2015. PLoS One. 10: 0131176. PubMed
  171. Honda H, et al. 2014. J Leukoc Biol. 96:1087. PubMed
  172. Drori A, et al. 2014. PLoS One. 9:110942. PubMed
  173. Quick M, et al. 2012. Am J Physiol Regul Integr Comp Physiol. 303:580. PubMed
  174. Dongsheng Z, et al. 2017. Inflammation. 10.1007/s10753-017-0619-0. PubMed
  175. Di G, et al. 2017. Invest Ophthalmol Vis Sci. 10.1167/iovs.17-21506. PubMed
  176. Xia Y, et al. 2018. Cell. 175:1059. PubMed
  177. Osorio K, et al. 2011. J Cell Biol. 193:235. PubMed
  178. Deng Q, et al. 2021. Gut Microbes. 13:1. PubMed
  179. Glasenapp A, et al. 2021. Circ Res. 129:369. PubMed
  180. Zheng X, et al. 2020. Int J Cancer. 146:1730. PubMed
  181. Chen Z, et al. 2016. PLoS One. 11: 0146681. PubMed
  182. Mothes B, et al. 2016. PLoS One. 11: 0159310. PubMed
  183. Yuan Y, et al. 2020. Front Physiol. 0.967361111. PubMed
  184. Bordas M, et al. 2020. Int J Mol Sci. 21:00. PubMed
  185. Lv JJ, et al. 2021. Front Cell Dev Biol. 8:609090. PubMed
  186. Yan T, et al. 2021. Toxicological Sciences. 181(2):273-284. PubMed
  187. Nasser H, et al. 2020. Cell Death Discov. 0.29375. PubMed
  188. Clemente–Casares X, et al. 2017. Immunity. 47:974. PubMed
  189. Lu Q, et al. 2022. Biomed Res Int. 2022:9427076. PubMed
  190. Nam J, et al. 2021. Adv Ther (Weinh). 4:. PubMed
  191. Howard ZM, et al. 2021. Am J Pathol. 191:730. PubMed
  192. Li Y, et al. 2020. Theranostics. 10:2897. PubMed
  193. Zhao H, et al. 2022. Commun Biol. 5:74. PubMed
  194. Lee SA, et al. 2021. Cells. 10:. PubMed
  195. Vaibhav K, et al. 2020. Sci Adv. 6:eaax8847. PubMed
  196. Zhou T, et al. 2021. Bioact Mater. 0.734027778. PubMed
  197. van Aalst S, et al. 2017. Vaccine. 10.1016/j.vaccine.2017.02.005. PubMed
  198. Meunier I, et al. 2015. PLoS One. 10: 0138055. PubMed
  199. Porrello A, et al. 2018. Nat Commun. 9:1988. PubMed
  200. Lancaster GI et al. 2018. Cell metabolism. 27(5):1096-1110 . PubMed
  201. Lang JF et al. 2019. Nat Commun. 10(1):3415 . PubMed
  202. Yoshida H, et al. 2019. Cell. 176:897. PubMed
  203. Kataru RP, et al. 2019. Cancer Immunol Res. 7:1345. PubMed
  204. Vazquez-Lombardi R, et al. 2017. Nat Commun. 8:15373. PubMed
  205. Morein D, et al. 2021. Cells. 10: . PubMed
  206. Sakurai Y, et al. 2021. Pharmaceutics. 13:. PubMed
  207. Zhang F, et al. 2021. J Immunol Res. 2021:5521051. PubMed
  208. Liu C, et al. 2022. Cell Death Discov. 8:269. PubMed
  209. Gautam S, et al. 2020. Am J Physiol Lung Cell Mol Physiol. 319:L661. PubMed
  210. Mujal AM, et al. 2022. Cancer Immunol Res. 10:403. PubMed
  211. Elias I, et al. 2012. Diabetes. 61:1801. PubMed
  212. Schaffert S, et al. 2015. J Immunol. 195: 1470-1479. PubMed
  213. Zhang J, et al. 2020. J Cell Mol Med. 24:4547. PubMed
  214. Rodriguez-Tirado C, et al. 2022. Cancers (Basel). 14:. PubMed
  215. Fite BZ, et al. 2021. Sci Rep. 11:927. PubMed
  216. Simoni L, et al. 2020. Cell Rep. 33:108330. PubMed
  217. Martins R, et al. 2016. Nat Immunol. 17:1361-1372. PubMed
  218. Kwon H, Kim S 2016. Cell Death Dis. 7:22285. PubMed
  219. Albaghdadi AJH, et al. 2019. Sci Rep. 9:6528. PubMed
  220. Li B et al. 2019. Cell reports. 26(10):2720-2737 . PubMed
  221. Li A, et al. 2018. Cancer Lett. 431:54. PubMed
  222. Kurelac I, et al. 2019. J Clin Med. 1.85. PubMed
  223. Krotova K, et al. 2019. Mol Ther Oncolytics. 15:166. PubMed
  224. Bhatia S, et al. 2019. Cancer Res. 79:2722. PubMed
  225. Lai NY, et al. 2020. Cell. 180:33:00. PubMed
  226. Caetano MS, et al. 2019. Clin Cancer Res. 25:7576. PubMed
  227. Guo Y, et al. 2021. Nat Immunol. 22:746. PubMed
  228. Bringmann G, et al. 2013. Antimicrob Agents Chemother. 57:3003. PubMed
  229. Tran S, et al. 2020. Immunity. 53(3):627-640.e5. PubMed
  230. Goldberg EL, et al. 2021. Cell Metabolism. :. PubMed
  231. Deniset JF et al. 2019. Immunity. 51(1):131-140 . PubMed
  232. Kubli SP, et al. 2019. Nat Commun. 10:2678. PubMed
  233. Song X, et al. 2022. Transl Oncol. 15:101306. PubMed
  234. Zhong J, et al. 2021. Commun Biol. 4:865. PubMed
  235. Xie Z, et al. 2020. Light Sci Appl. 9:161. PubMed
  236. Yang F, et al. 2021. Nat Commun. 12:3424. PubMed
  237. Cortez MA, et al. 2020. Nat Commun. 3.819444444. PubMed
  238. Uematsu T, et al. 2015. Sci Rep. 5: 17577. PubMed
  239. Wegiel B, et al. 2014. Cell Death Dis. 5:1139. PubMed
  240. Richardson M, et al. 2014. PLoS Negl Trop Dis. 8:2825. PubMed
RRID
AB_893500 (BioLegend Cat. No. 123107)
AB_893502 (BioLegend Cat. No. 123108)

Antigen Details

Structure
EGF-TM7 family member, 160 kD glycoprotein
Distribution

Majority of tissue macrophages including peritoneal macrophages, macrophages in lung, gut, thymus and red pulp of spleen, Kupffer cells, Langerhans cells, bone marrow stromal cells, and a subset of dendritic cells

Function
Induction of immunological tolerance
Cell Type
Dendritic cells, Langerhans cells, Macrophages, Tregs
Biology Area
Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience
Antigen References

1. Austy JM and Gordon S. 1981. Eur. J. Immunol. 11:805.
2. Hume DA, et al. 1983. J. Exp. Med. 158:1522.
3. Ruedl C, et al. 1996. Eur. J. Immunol. 26:1801.
4. McKnight AJ, et al. 1996. J. Biol. Chem. 271:486.
5. Lin HH, et al. 2005. J. Exp. Med. 201:1615.

Gene ID
13733 View all products for this Gene ID
UniProt
View information about F4/80 on UniProt.org

Related FAQs

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Other Formats

View All F4/80 Reagents Request Custom Conjugation
Description Clone Applications
Brilliant Violet 605™ anti-mouse F4/80 BM8 FC
Purified anti-mouse F4/80 BM8 FC,IHC,WB
Biotin anti-mouse F4/80 BM8 FC,IHC
FITC anti-mouse F4/80 BM8 FC
PE anti-mouse F4/80 BM8 FC
PE/Cyanine5 anti-mouse F4/80 BM8 FC
PE/Cyanine7 anti-mouse F4/80 BM8 FC
APC anti-mouse F4/80 BM8 FC
APC/Cyanine7 anti-mouse F4/80 BM8 FC
Alexa Fluor® 488 anti-mouse F4/80 BM8 FC,IHC-F,3D IHC
Alexa Fluor® 647 anti-mouse F4/80 BM8 FC,IHC-F,3D IHC
Pacific Blue™ anti-mouse F4/80 BM8 FC
PerCP anti-mouse F4/80 BM8 FC
PerCP/Cyanine5.5 anti-mouse F4/80 BM8 FC
Alexa Fluor® 700 anti-mouse F4/80 BM8 FC
Brilliant Violet 421™ anti-mouse F4/80 BM8 FC,IHC-F,SB
Brilliant Violet 510™ anti-mouse F4/80 BM8 FC
Alexa Fluor® 594 anti-mouse F4/80 BM8 IHC-F
Brilliant Violet 785™ anti-mouse F4/80 BM8 FC
Purified anti-mouse F4/80 (Maxpar® Ready) BM8 FC,CyTOF®
PE/Dazzle™ 594 anti-mouse F4/80 BM8 FC
Brilliant Violet 650™ anti-mouse F4/80 BM8 FC
Brilliant Violet 711™ anti-mouse F4/80 BM8 FC
APC/Fire™ 750 anti-mouse F4/80 BM8 FC
TotalSeq™-A0114 anti-mouse F4/80 BM8 PG
TotalSeq™-B0114 anti-mouse F4/80 BM8 PG
TotalSeq™-C0114 anti-mouse F4/80 BM8 PG
Spark YG™ 570 anti-mouse F4/80 BM8 IHC-F
KIRAVIA Blue 520™ anti-mouse F4/80 BM8 FC
Ultra-LEAF™ Purified anti-mouse F4/80 BM8 FC,IHC,WB
APC/Fire™ 810 anti-mouse F4/80 BM8 FC
Spark NIR™ 685 anti-mouse F4/80 BM8 FC
Spark Blue™ 550 anti-mouse F4/80 BM8 FC
Brilliant Violet 570™ anti-mouse F4/80 BM8 FC
Brilliant Violet 750™ anti-mouse F4/80 BM8 FC
PE/Fire™ 810 anti-mouse F4/80 BM8 FC
Go To Top Version: 2    Revision Date: 10-25-2013

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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