APC anti-mouse CD36 Antibody

Pricing & Availability
Clone
HM36 (See other available formats)
Other Names
FAT, gpIIIb, gpIV
Isotype
Armenian Hamster IgG
Ave. Rating
1 reviews
Product Citations
publications
HM36_APC_022607
Thioglycollate-elicited BALB/c mouse peritoneal macrophages stained with HM36 APC
  • HM36_APC_022607
    Thioglycollate-elicited BALB/c mouse peritoneal macrophages stained with HM36 APC
See APC spectral data
Cat # Size Price Quantity Avail. Save
102611 25 µg $85
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102612 100 µg $265
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Description

CD36 is a 85 kD glycoprotein, also known as FAT, gpIIIb, or gpIV. It is a member of the class B scavenger receptor family, expressed on platelets, monocytes, macrophages, megakaryocytes, microvasculature, dendritic cells and mammary endothelial cells. The primary ligands for CD36 have been reported to be oxidized low density lipoprotein, anionic phospholipids, and collagens I, IV, and V. CD36 acts as a scavenger receptor thus promoting the removal of apoptotic neutrophils and other apoptotic bodies, as well as clearance of defective erythrocytes.

Product Details
Technical data sheet

Product Details

Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Armenian Hamster
Immunogen
Full length version of the protein
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Excitation Laser
Red Laser (633 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Hamilton R F, 2006. J. Biol. Chem. 281:34218.
  2. Stuart L M, 2007. J. Biol. Chem. doi:10.1074/jbc.M702887200.
Product Citations
  1. Hickman S, et al. 2008. J Neurosci. 28:8354. PubMed
  2. Singhal P, et al. 2016. Proc Natl Acad Sci U S A. 113: 122 - 127. PubMed
  3. De Silva N, et al. 2016. Proc Natl Acad Sci U S A. 113: 9063 - 9068. PubMed
  4. Macdougall CE et al. 2018. Cell metabolism. 27(3):588-601 . PubMed
  5. Miska J et al. 2019. Cell reports. 27(1):226-237 . PubMed
  6. Misumi I et al. 2019. Cell Rep. 27(2):514-524 . PubMed
RRID
AB_571994 (BioLegend Cat. No. 102611)
AB_2072639 (BioLegend Cat. No. 102612)

Antigen Details

Structure
Scavenger receptor superfamily, 85 kD
Distribution
Platelets, monocytes, macrophages, microvascular and mammary endothelial cells
Function
Scavenger receptor, recognition and phagocytosis of apoptotic neutrophils, adhesion
Ligand/Receptor
Oxidized low density lipoprotein, anionic phospholipids, collagen I, IV, and V
Cell Type
Endothelial cells, Macrophages, Monocytes, Platelets
Biology Area
Immunology, Innate Immunity
Molecular Family
CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Greenwalt DE, et al. 1992. Blood 80:1105.
3. Endemann G, et al. 1993. J. Biol. Chem. 268:11811.

Gene ID
12491 View all products for this Gene ID
UniProt
View information about CD36 on UniProt.org

Reviews

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Go To Top Version: 1    Revision Date: 11/30/2012

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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